Hamilton Company Datasheets for HPLC Columns

High performance liquid chromatography (HPLC) columns use a liquid mobile phase to separate the components of a mixture.
HPLC Columns: Learn more

Product Name Notes
HxSil C18 3 µm 2.1 x 50 mm -- 79889
HxSil C18 5 µm 4.6 x 150 mm -- 79868
HxSil C18 5 µm 4.6 x 250 mm -- 79869
HxSil C18 Analytical Replacement Cart. -- 79452
HxSil C18 Analytical Starter Kit -- 79459
HxSil C18 Semiprep/Preparative -- 79138
HxSil C18 Semiprep/Preparative Kit -- 79137
Hamilton HxSil C18 columns are well end-capped for retention time reproducibility and durability. HxSil C18 columns exhibit greater retention than most columns and enhances the separation of compounds that are...
HxSil C8 Analytical Replacement Cart. -- 79451
HxSil C8 Analytical Starter Kit -- 79458
HxSil C8 Semiprep/Preparative -- 79136
HxSil C8 Semiprep/Preparative Kit -- 79135
Hamilton HxSil C8 columns are well end-capped for retention time reproducibility and durability. The C8 demonstrates excellent selectivity needed for complex sample mixtures and gives shorter retention times than a...
PRP-X200 10 µm 2.1 x 150 mm -- 79394
PRP-X200 10 µm 4.1 x 100 mm -- 79363
PRP-X200 10 µm 4.1 x 150 mm -- 79441
PRP-X200 10 µm 4.1 x 250 mm -- 79442
PRP-X200 10 µm 4.6 x 150 mm PEEK -- 79384
PRP-X200 10 µm 4.6 x 250 mm PEEK -- 79357
PRP-X200 Replacement Cartridges (5/pk -- 79369
PRP-X200 Replacement Cartridges (5/pk) -- 79449
PRP-X200 Starter Kit -- 79368
PRP-X200 Starter Kit -- 79456
Hamilton PRP-X200 cation exchange HPLC columns are designed for rapid, high resolution separation of alkali and alkaline earth metals. The alkali metals and ammonium are completely resolved in less than...
PRP-X300 7 µm 4.1 x 150 mm -- 79464
PRP-X300 7 µm 4.1 x 250 mm -- 79465
PRP-X300 7 µm 4.6 x 150 mm PEEK -- 79475
PRP-X300 Replacement Cartridges (2/pk) -- 79130
PRP-X300 Replacement Cartridges (5/pk) -- 79374
PRP-X300 Replacement Cartridges (5/pk) -- 79453
PRP-X300 Starter Kit -- 79129
PRP-X300 Starter Kit -- 79373
PRP-X300 Starter Kit -- 79460
Hamilton PRP-X300 columns offer an easy, rapid way to separate closely related alcohols and organic acids. The sulfonated poly(styrene-divinylbenzene) support separates samples via a mixed mode mechanism. Separation on the...
PRP-3 10 µm 10 x 250 mm -- 79526
PRP-3 10 µm 2.1 x 150 mm -- 79392
PRP-3 10 µm 21.5 x 250 mm -- 79147
PRP-3 10 µm 4.1 x 150 mm -- 79466
PRP-3 10 µm 4.1 x 250 mm -- 79794
PRP-3 10 µm 4.6 x 150 mm PEEK -- 79382
PRP-3 10 µm 4.6 x 250 mm PEEK -- 79574
PRP-3 10 µm 7.0 x 305 mm -- 79468
PRP-3 12-20 µm 21.2 x 100 mm -- 79186
PRP-3 12-20 µm 21.2 x 250 mm -- 79469
PRP-3 Analytical Replacement Cartridge -- 79395
PRP-3 Analytical Replacement Cartridges -- 79454
PRP-3 Analytical Starter Kit -- 79393
PRP-3 Analytical Starter Kit -- 79461
PRP-3 Semiprep/Preparative -- 79124
PRP-3 Semiprep/Preparative Starter Kit -- 79123
Hamilton’s PRP-3 is a polymeric reversed-phase HPLC column designed for the purification and isolation of proteins and peptides with very good recovery (> 90%). It is based off of the...
Carbonate Form Replacement Cartridges -- 79865
Carbonate Form Starter Kit -- 79866
HC-75 (Ca2+) 9 µm 4.1 x 250 mm -- 79431
HC-75 (Ca2+) 9 µm 7.8 x 305 mm -- 79436
HC-75 (H+) 9 µm 4.1 x 250 mm -- 79476
HC-75 (H+) 9 µm 7.8 x 100 mm -- 79547
HC-75 (H+) 9 µm 7.8 x 305 mm -- 79544
HC-75 (Pb2+) 9 µm 7.8 x 100 mm -- 79240
HC-75 (Pb2+) 9 µm 7.8 x 305 mm -- 79438
PRP-X400, H+ Replacement Cartridge -- 79134
PRP-X400, H+ Starter Kit -- 79133
HC-75 columns separate compounds through ligand exchange. The 8% cross-linked HC-75 uses ligand exchange as the primary mechanism of separation. The different forms of the HC-75 (Hydrogen, Calcium and Lead)...
PRP-X100 10 µm 2.1 x 150 mm -- 79421
PRP-X100 10 µm 2.1 x 250 mm -- 79346
PRP-X100 10 µm 4.1 x 100 mm -- 79439
PRP-X100 10 µm 4.1 x 150 mm -- 79434
PRP-X100 10 µm 4.1 x 250 mm -- 79433
PRP-X100 10 µm 4.1 x 50 mm -- 79365
PRP-X100 10 µm 4.6 x 150 mm PEEK -- 79354
PRP-X100 10 µm 4.6 x 250 mm PEEK -- 79455
PRP-X100 12-20 µm 21.5 x 250 mm -- 79353
PRP-X100 5 µm 2.1 x 150 mm PEEK -- 79852
PRP-X100 5 µm 2.1 x 250 mm -- 79190
PRP-X100 5 µm 4.1 x 100 mm -- 79538
PRP-X100 5 µm 4.1 x 150 mm -- 79812
PRP-X100 5 µm 4.1 x 50 mm -- 79810
PRP-X100 5 µm 4.6 x 150 mm PEEK -- 79174
PRP-X100 5 µm 4.6 x 250 mm PEEK -- 79181
PRP-X100 Analytical Replacement Cart. -- 79385
PRP-X100 Analytical Replacement Cart. -- 79446
PRP-X100 Analytical Starter Kit -- 79383
PRP-X100 Analytical Starter Kit -- 79448
PRP-X100 Semiprep/Preparative -- 79126
PRP-X100 Semiprep/Preparative Kit -- 79125
PRP-X110 7 µm 4.1 x 150 mm -- 79732
PRP-X110 7 µm 4.1 x 250 mm -- 79734
PRP-X110 7 µm 4.6 x 150 mm PEEK -- 79738
PRP-X110 Replacement Cartridges (5/pk) -- 79728
PRP-X110 Replacement Cartridges (5/pk) -- 79729
PRP-X110 Starter Kit -- 79726
PRP-X110 Starter Kit -- 79727
PRP-X110S 7 µm 2.1 x 100 mm PEEK -- 79743
PRP-X110S 7 µm 4.1 x 150 mm -- 79733
PRP-X110S 7 µm 4.1x 250 mm -- 79735
PRP-X110S 7 µm 4.6 x 250 mm PEEK -- 79741
PRP-X100 and PRP-X110 columns are well suited for use in systems employing suppressed/non-suppressed conductivity, electrochemical, UV, and ICP-MS detection.
PRP-X500 7 µm 4.6 x 150 mm -- 79573
PRP-X500 Replacement Cartridges (5/pk) -- 79320
PRP-X500 Starter Kit -- 79319
PRP-X500 is a superficially porous polymeric anion exchange column designed for the separation, purification and isolation of proteins, peptides and DNA/RNA. The methacrylate polymeric coating of the PRP-X500 provides a...
PRP-X600 7 µm 4.6 x 250 mm PEEK -- 79189
PRP-X600 7 µm 4.6 x 50 mm PEEK -- 79360
PRP-X600 Replacement Cartridges (5/pk) -- 79362
PRP-X600 Starter Kit -- 79361
PRP-X600 is a superficially porous weak-base anion exchange support that separates DNA oligomers according to negative charge. The unique porosity provides fast separation with better sample capacity than non-porous supports.
PRP-1 10 µm 10 x 100 mm -- 79499
PRP-1 10 µm 10 x 250 mm -- 79496
PRP-1 10 µm 21.5 x 250 mm -- 79478
PRP-1 10 µm 4.1 x 150 mm -- 79425
PRP-1 10 µm 4.1 x 250 mm -- 79427
PRP-1 10 µm 4.6 x 150 mm PEEK -- 79351
PRP-1 10 µm 4.6 x 250 mm PEEK -- 79381
PRP-1 10 µm 50 x 250 mm -- 79567
PRP-1 10 µm 7 x 100 mm -- 79495
PRP-1 10 µm 7 x 305 mm -- 79426
PRP-1 12-20 µm 101.6 x 250 mm -- 79525
PRP-1 12-20 µm 101.6 x 250 mm -- 79800
PRP-1 12-20 µm 21.5 x 250 mm -- 79428
PRP-1 12-20 µm 30 x 250 mm -- 79229
PRP-1 12-20 µm 50 x 250 mm -- 79493
PRP-1 5 µm 1.0 x 150 mm -- 79753
PRP-1 5 µm 10.0 x 100 mm -- 79355
PRP-1 5 µm 2.1 x 100 mm -- 79790
PRP-1 5 µm 2.1 x 150 mm -- 79366
PRP-1 5 µm 21.5 x 75 mm -- 79154
PRP-1 5 µm 4.1 x 100 mm -- 79479
PRP-1 5 µm 4.1 x 150 mm -- 79444
PRP-1 5 µm 4.1 x 250 mm -- 79820
PRP-1 5 µm 4.1 x 50 mm -- 79443
PRP-1 5 µm 4.6 x 100 mm PEEK -- 79558
PRP-1 5 µm 4.6 x 150 mm PEEK -- 79423
PRP-1 5 µm 4.6 x 250 mm PEEK -- 79571
PRP-1 5 µm 7.0 x 305 mm -- 79795
PRP-1 7 µm 10 x 250 mm -- 79531
PRP-1 7 µm 21.5 x 250 mm -- 79352
PRP-1 7 µm 4.1 x 150 mm -- 79529
PRP-1 7 µm 4.1 x 250 mm -- 79422
PRP-1 7 µm 4.6 x 250 mm PEEK -- 79380
PRP-1 Analytical Replacement Cartridge -- 79318
PRP-1 Analytical Replacement Cartridge -- 79445
PRP-1 Analytical Starter Kit -- 79317
PRP-1 Analytical Starter Kit -- 79447
PRP-1 Semiprep/Preparative -- 79122
PRP-1 Semiprep/Preparative Starter Kit -- 79121
Sample recovery is vital to sample purification. Problems arise when labile samples become irreversibly bound to the silanol groups present on C8 and C18 HPLC columns. Since Hamilton polymers are...
PRP-C18, 5 µm, 100 Å, 4.6 x 50 mm -- 79675
PRP-C18, 10 µm, 100 Å, Bulk Resin (1 gram) -- 79792
PRP-C18, 12-20 µm, 100 Å, 21.2 x 250 mm -- 79678
PRP-C18, 12-20 µm, 100 Å, Bulk Resin (1 gram) -- 79793
PRP-C18, 5 µm, 100 Å, 2.1 x 150 mm -- 79673
PRP-C18, 5 µm, 100 Å, 2.1 x 150 mm PEEK -- 79680
PRP-C18, 5 µm, 100 Å, 2.1 x 250 mm -- 79674
PRP-C18, 5 µm, 100 Å, 2.1 x 250 mm PEEK -- 79681
PRP-C18, 5 µm, 100 Å, 2.1 x 50 mm -- 79672
PRP-C18, 5 µm, 100 Å, 2.1 x 50 mm PEEK -- 79679
PRP-C18, 5 µm, 100 Å, 4.6 x 150 mm -- 79676
PRP-C18, 5 µm, 100 Å, 4.6 x 150 mm PEEK -- 79683
PRP-C18, 5 µm, 100 Å, 4.6 x 250 mm -- 79677
PRP-C18, 5 µm, 100 Å, 4.6 x 250 mm PEEK -- 79684
PRP-C18, 5 µm, 100 Å, 4.6 x 50 mm PEEK -- 79682
PRP-C18, 5 µm, 100 Å, Bulk Resin (1 gram) -- 79791
PRP-C18, Analytical Guard Column Replacement Cartridges (5/pk), PEEK -- 79688
PRP-C18, Analytical Guard Column Replacement Cartridges (5/pk), Stainless Steel -- 79686
PRP-C18, Analytical Guard Column Starter Kit (1 holder, 2 cartridges), PEEK -- 79687
PRP-C18, Analytical Guard Column Starter Kit (1 holder, 2 cartridges), Stainless Steel -- 79685
PRP-C18, Semiprep/Preparative Guard Column Replacement Cartridges (2/pk), Stainless Steel -- 79690
PRP-C18, Semiprep/Preparative Guard Column Starter Kit (1 holder, 1 cartridge), Stainless Steel -- 79689
The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase...
RCX-10 7 µm 4.1 x 250 mm -- 79440
RCX-10 7 µm 4.6 x 250 mm PEEK -- 79388
RCX-10 Replacement Cartridges (5/pk) -- 79379
RCX-10 Replacement Cartridges (5/pk) -- 79463
RCX-10 Starter Kit -- 79378
RCX-10 Starter Kit -- 79462
RCX-30 7 µm 4.1 x 250 mm -- 79803
RCX-30 7 µm 4.6 x 150 mm PEEK -- 79370
RCX-30 7 µm 4.6 x 250 mm PEEK -- 79877
RCX-30 Replacement Cartridges (5/pk) -- 79372
RCX-30 Starter Kit -- 79371
The Hamilton RCX-10 and RCX-30 carbohydrate analysis columns are designed for the isocratic or gradient separation of carbohydrates. The exchange capacity of the RCX-10/RCX-30 is greater than that of the...
PRP-h5 5 µm 10 x 100 mm -- 79263
PRP-h5 5 µm 10 x 150 mm -- 79274
PRP-h5 5 µm 2.1 x 100 mm -- 79270
PRP-h5 5 µm 2.1 x 150 mm -- 79271
PRP-h5 5 µm 4.6 x 100 mm -- 79262
PRP-h5 5 µm 4.6 x 150 mm -- 79272
PRP-h5 5 µm 4.6 x 250 mm -- 79273
PRP-h5 5 µm 4.6 x 50 mm -- 79261
PRP-h5 Analytical Guard Column Kit -- 79267
PRP-h5 Analytical Replacement Cartridge -- 79268
PRP-h5 Semiprep/Prep Guard Column Kit -- 79277
PRP-h5 Semiprep/Prep Replacement Cart. -- 79278
The PRP-h5 utilizes the PRP-3 as its base with a pentafluorinated modification, making it more hydrophobic in nature. The PRP-h5, with its functionality derived from a pentafluorinated polymer bead, delivers...
PRP-X400 7 µm 2.1 x 250 mm -- 79398
PRP-X400 7 µm 4.1 x 150 mm -- 79717
PRP-X400 7 µm 4.1 x 250 mm -- 79473
PRP-X400 7 µm 4.6 x 250 mm PEEK -- 79387
PRP-X400 Analytical Replacement Cart. -- 79377
PRP-X400 Analytical Starter Kit -- 79376
PRP-X400 Semiprep/Preparative -- 79132
PRP-X400 Semiprep/Preparative Kit -- 79131
The PRP-X400 column provides a fast separation for glyphosate and its metabolites. The exchange capacity of the PRP-X400 is greater than that of the PRP-X200, leading to characteristics better suited...
PRP-X800 7 µm 4.1 x 150 mm -- 79855
PRP-X800 7 µm 4.1 x 250 mm -- 79828
PRP-X800 Analytical Replacement Cart. -- 79832
PRP-X800 Analytical Replacement Cart. -- 79833
PRP-X800 Analytical Starter Kit -- 79830
PRP-X800 Analytical Starter Kit -- 79831
The PRP-X800 is a polymeric cation exchange column functionalized with itaconic acid that performs the isocratic separation of mono and divalent cations such as lithium, sodium, ammonium, potassium, magnesium and...