Hamilton Company Datasheets for HPLC Columns

High performance liquid chromatography (HPLC) columns use a liquid mobile phase to separate the components of a mixture.
HPLC Columns: Learn more

Product Name	Notes
HxSil C18 3 µm 2.1 x 50 mm -- 79889 HxSil C18 5 µm 4.6 x 150 mm -- 79868 HxSil C18 5 µm 4.6 x 250 mm -- 79869 HxSil C18 Analytical Replacement Cart. -- 79452 HxSil C18 Analytical Starter Kit -- 79459 HxSil C18 Semiprep/Preparative -- 79138 HxSil C18 Semiprep/Preparative Kit -- 79137	Hamilton HxSil C18 columns are well end-capped for retention time reproducibility and durability. HxSil C18 columns exhibit greater retention than most columns and enhances the separation of compounds that are...
HxSil C8 Analytical Replacement Cart. -- 79451 HxSil C8 Analytical Starter Kit -- 79458 HxSil C8 Semiprep/Preparative -- 79136 HxSil C8 Semiprep/Preparative Kit -- 79135	Hamilton HxSil C8 columns are well end-capped for retention time reproducibility and durability. The C8 demonstrates excellent selectivity needed for complex sample mixtures and gives shorter retention times than a...
PRP-X200 10 µm 2.1 x 150 mm -- 79394 PRP-X200 10 µm 4.1 x 100 mm -- 79363 PRP-X200 10 µm 4.1 x 150 mm -- 79441 PRP-X200 10 µm 4.1 x 250 mm -- 79442 PRP-X200 10 µm 4.6 x 150 mm PEEK -- 79384 PRP-X200 10 µm 4.6 x 250 mm PEEK -- 79357 PRP-X200 Replacement Cartridges (5/pk -- 79369 PRP-X200 Replacement Cartridges (5/pk) -- 79449 PRP-X200 Starter Kit -- 79368 PRP-X200 Starter Kit -- 79456	Hamilton PRP-X200 cation exchange HPLC columns are designed for rapid, high resolution separation of alkali and alkaline earth metals. The alkali metals and ammonium are completely resolved in less than...
PRP-X300 7 µm 4.1 x 150 mm -- 79464 PRP-X300 7 µm 4.1 x 250 mm -- 79465 PRP-X300 7 µm 4.6 x 150 mm PEEK -- 79475 PRP-X300 Replacement Cartridges (2/pk) -- 79130 PRP-X300 Replacement Cartridges (5/pk) -- 79374 PRP-X300 Replacement Cartridges (5/pk) -- 79453 PRP-X300 Starter Kit -- 79129 PRP-X300 Starter Kit -- 79373 PRP-X300 Starter Kit -- 79460	Hamilton PRP-X300 columns offer an easy, rapid way to separate closely related alcohols and organic acids. The sulfonated poly(styrene-divinylbenzene) support separates samples via a mixed mode mechanism. Separation on the...
PRP-3 10 µm 10 x 250 mm -- 79526 PRP-3 10 µm 2.1 x 150 mm -- 79392 PRP-3 10 µm 21.5 x 250 mm -- 79147 PRP-3 10 µm 4.1 x 150 mm -- 79466 PRP-3 10 µm 4.1 x 250 mm -- 79794 PRP-3 10 µm 4.6 x 150 mm PEEK -- 79382 PRP-3 10 µm 4.6 x 250 mm PEEK -- 79574 PRP-3 10 µm 7.0 x 305 mm -- 79468 PRP-3 12-20 µm 21.2 x 100 mm -- 79186 PRP-3 12-20 µm 21.2 x 250 mm -- 79469 PRP-3 Analytical Replacement Cartridge -- 79395 PRP-3 Analytical Replacement Cartridges -- 79454 PRP-3 Analytical Starter Kit -- 79393 PRP-3 Analytical Starter Kit -- 79461 PRP-3 Semiprep/Preparative -- 79124 PRP-3 Semiprep/Preparative Starter Kit -- 79123	Hamilton’s PRP-3 is a polymeric reversed-phase HPLC column designed for the purification and isolation of proteins and peptides with very good recovery (> 90%). It is based off of the...
Carbonate Form Replacement Cartridges -- 79865 Carbonate Form Starter Kit -- 79866 HC-75 (Ca2+) 9 µm 4.1 x 250 mm -- 79431 HC-75 (Ca2+) 9 µm 7.8 x 305 mm -- 79436 HC-75 (H+) 9 µm 4.1 x 250 mm -- 79476 HC-75 (H+) 9 µm 7.8 x 100 mm -- 79547 HC-75 (H+) 9 µm 7.8 x 305 mm -- 79544 HC-75 (Pb2+) 9 µm 7.8 x 100 mm -- 79240 HC-75 (Pb2+) 9 µm 7.8 x 305 mm -- 79438 PRP-X400, H+ Replacement Cartridge -- 79134 PRP-X400, H+ Starter Kit -- 79133	HC-75 columns separate compounds through ligand exchange. The 8% cross-linked HC-75 uses ligand exchange as the primary mechanism of separation. The different forms of the HC-75 (Hydrogen, Calcium and Lead)...
PRP-X100 10 µm 2.1 x 150 mm -- 79421 PRP-X100 10 µm 2.1 x 250 mm -- 79346 PRP-X100 10 µm 4.1 x 100 mm -- 79439 PRP-X100 10 µm 4.1 x 150 mm -- 79434 PRP-X100 10 µm 4.1 x 250 mm -- 79433 PRP-X100 10 µm 4.1 x 50 mm -- 79365 PRP-X100 10 µm 4.6 x 150 mm PEEK -- 79354 PRP-X100 10 µm 4.6 x 250 mm PEEK -- 79455 PRP-X100 12-20 µm 21.5 x 250 mm -- 79353 PRP-X100 5 µm 2.1 x 150 mm PEEK -- 79852 PRP-X100 5 µm 2.1 x 250 mm -- 79190 PRP-X100 5 µm 4.1 x 100 mm -- 79538 PRP-X100 5 µm 4.1 x 150 mm -- 79812 PRP-X100 5 µm 4.1 x 50 mm -- 79810 PRP-X100 5 µm 4.6 x 150 mm PEEK -- 79174 PRP-X100 5 µm 4.6 x 250 mm PEEK -- 79181 PRP-X100 Analytical Replacement Cart. -- 79385 PRP-X100 Analytical Replacement Cart. -- 79446 PRP-X100 Analytical Starter Kit -- 79383 PRP-X100 Analytical Starter Kit -- 79448 PRP-X100 Semiprep/Preparative -- 79126 PRP-X100 Semiprep/Preparative Kit -- 79125 PRP-X110 7 µm 4.1 x 150 mm -- 79732 PRP-X110 7 µm 4.1 x 250 mm -- 79734 PRP-X110 7 µm 4.6 x 150 mm PEEK -- 79738 PRP-X110 Replacement Cartridges (5/pk) -- 79728 PRP-X110 Replacement Cartridges (5/pk) -- 79729 PRP-X110 Starter Kit -- 79726 PRP-X110 Starter Kit -- 79727 PRP-X110S 7 µm 2.1 x 100 mm PEEK -- 79743 PRP-X110S 7 µm 4.1 x 150 mm -- 79733 PRP-X110S 7 µm 4.1x 250 mm -- 79735 PRP-X110S 7 µm 4.6 x 250 mm PEEK -- 79741	PRP-X100 and PRP-X110 columns are well suited for use in systems employing suppressed/non-suppressed conductivity, electrochemical, UV, and ICP-MS detection.
PRP-X500 7 µm 4.6 x 150 mm -- 79573 PRP-X500 Replacement Cartridges (5/pk) -- 79320 PRP-X500 Starter Kit -- 79319	PRP-X500 is a superficially porous polymeric anion exchange column designed for the separation, purification and isolation of proteins, peptides and DNA/RNA. The methacrylate polymeric coating of the PRP-X500 provides a...
PRP-X600 7 µm 4.6 x 250 mm PEEK -- 79189 PRP-X600 7 µm 4.6 x 50 mm PEEK -- 79360 PRP-X600 Replacement Cartridges (5/pk) -- 79362 PRP-X600 Starter Kit -- 79361	PRP-X600 is a superficially porous weak-base anion exchange support that separates DNA oligomers according to negative charge. The unique porosity provides fast separation with better sample capacity than non-porous supports.
PRP-1 10 µm 10 x 100 mm -- 79499 PRP-1 10 µm 10 x 250 mm -- 79496 PRP-1 10 µm 21.5 x 250 mm -- 79478 PRP-1 10 µm 4.1 x 150 mm -- 79425 PRP-1 10 µm 4.1 x 250 mm -- 79427 PRP-1 10 µm 4.6 x 150 mm PEEK -- 79351 PRP-1 10 µm 4.6 x 250 mm PEEK -- 79381 PRP-1 10 µm 50 x 250 mm -- 79567 PRP-1 10 µm 7 x 100 mm -- 79495 PRP-1 10 µm 7 x 305 mm -- 79426 PRP-1 12-20 µm 101.6 x 250 mm -- 79525 PRP-1 12-20 µm 101.6 x 250 mm -- 79800 PRP-1 12-20 µm 21.5 x 250 mm -- 79428 PRP-1 12-20 µm 30 x 250 mm -- 79229 PRP-1 12-20 µm 50 x 250 mm -- 79493 PRP-1 5 µm 1.0 x 150 mm -- 79753 PRP-1 5 µm 10.0 x 100 mm -- 79355 PRP-1 5 µm 2.1 x 100 mm -- 79790 PRP-1 5 µm 2.1 x 150 mm -- 79366 PRP-1 5 µm 21.5 x 75 mm -- 79154 PRP-1 5 µm 4.1 x 100 mm -- 79479 PRP-1 5 µm 4.1 x 150 mm -- 79444 PRP-1 5 µm 4.1 x 250 mm -- 79820 PRP-1 5 µm 4.1 x 50 mm -- 79443 PRP-1 5 µm 4.6 x 100 mm PEEK -- 79558 PRP-1 5 µm 4.6 x 150 mm PEEK -- 79423 PRP-1 5 µm 4.6 x 250 mm PEEK -- 79571 PRP-1 5 µm 7.0 x 305 mm -- 79795 PRP-1 7 µm 10 x 250 mm -- 79531 PRP-1 7 µm 21.5 x 250 mm -- 79352 PRP-1 7 µm 4.1 x 150 mm -- 79529 PRP-1 7 µm 4.1 x 250 mm -- 79422 PRP-1 7 µm 4.6 x 250 mm PEEK -- 79380 PRP-1 Analytical Replacement Cartridge -- 79318 PRP-1 Analytical Replacement Cartridge -- 79445 PRP-1 Analytical Starter Kit -- 79317 PRP-1 Analytical Starter Kit -- 79447 PRP-1 Semiprep/Preparative -- 79122 PRP-1 Semiprep/Preparative Starter Kit -- 79121	Sample recovery is vital to sample purification. Problems arise when labile samples become irreversibly bound to the silanol groups present on C8 and C18 HPLC columns. Since Hamilton polymers are...
PRP-C18, 5 µm, 100 Å, 4.6 x 50 mm -- 79675 PRP-C18, 10 µm, 100 Å, Bulk Resin (1 gram) -- 79792 PRP-C18, 12-20 µm, 100 Å, 21.2 x 250 mm -- 79678 PRP-C18, 12-20 µm, 100 Å, Bulk Resin (1 gram) -- 79793 PRP-C18, 5 µm, 100 Å, 2.1 x 150 mm -- 79673 PRP-C18, 5 µm, 100 Å, 2.1 x 150 mm PEEK -- 79680 PRP-C18, 5 µm, 100 Å, 2.1 x 250 mm -- 79674 PRP-C18, 5 µm, 100 Å, 2.1 x 250 mm PEEK -- 79681 PRP-C18, 5 µm, 100 Å, 2.1 x 50 mm -- 79672 PRP-C18, 5 µm, 100 Å, 2.1 x 50 mm PEEK -- 79679 PRP-C18, 5 µm, 100 Å, 4.6 x 150 mm -- 79676 PRP-C18, 5 µm, 100 Å, 4.6 x 150 mm PEEK -- 79683 PRP-C18, 5 µm, 100 Å, 4.6 x 250 mm -- 79677 PRP-C18, 5 µm, 100 Å, 4.6 x 250 mm PEEK -- 79684 PRP-C18, 5 µm, 100 Å, 4.6 x 50 mm PEEK -- 79682 PRP-C18, 5 µm, 100 Å, Bulk Resin (1 gram) -- 79791 PRP-C18, Analytical Guard Column Replacement Cartridges (5/pk), PEEK -- 79688 PRP-C18, Analytical Guard Column Replacement Cartridges (5/pk), Stainless Steel -- 79686 PRP-C18, Analytical Guard Column Starter Kit (1 holder, 2 cartridges), PEEK -- 79687 PRP-C18, Analytical Guard Column Starter Kit (1 holder, 2 cartridges), Stainless Steel -- 79685 PRP-C18, Semiprep/Preparative Guard Column Replacement Cartridges (2/pk), Stainless Steel -- 79690 PRP-C18, Semiprep/Preparative Guard Column Starter Kit (1 holder, 1 cartridge), Stainless Steel -- 79689	The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase...
RCX-10 7 µm 4.1 x 250 mm -- 79440 RCX-10 7 µm 4.6 x 250 mm PEEK -- 79388 RCX-10 Replacement Cartridges (5/pk) -- 79379 RCX-10 Replacement Cartridges (5/pk) -- 79463 RCX-10 Starter Kit -- 79378 RCX-10 Starter Kit -- 79462 RCX-30 7 µm 4.1 x 250 mm -- 79803 RCX-30 7 µm 4.6 x 150 mm PEEK -- 79370 RCX-30 7 µm 4.6 x 250 mm PEEK -- 79877 RCX-30 Replacement Cartridges (5/pk) -- 79372 RCX-30 Starter Kit -- 79371	The Hamilton RCX-10 and RCX-30 carbohydrate analysis columns are designed for the isocratic or gradient separation of carbohydrates. The exchange capacity of the RCX-10/RCX-30 is greater than that of the...
PRP-h5 5 µm 10 x 100 mm -- 79263 PRP-h5 5 µm 10 x 150 mm -- 79274 PRP-h5 5 µm 2.1 x 100 mm -- 79270 PRP-h5 5 µm 2.1 x 150 mm -- 79271 PRP-h5 5 µm 4.6 x 100 mm -- 79262 PRP-h5 5 µm 4.6 x 150 mm -- 79272 PRP-h5 5 µm 4.6 x 250 mm -- 79273 PRP-h5 5 µm 4.6 x 50 mm -- 79261 PRP-h5 Analytical Guard Column Kit -- 79267 PRP-h5 Analytical Replacement Cartridge -- 79268 PRP-h5 Semiprep/Prep Guard Column Kit -- 79277 PRP-h5 Semiprep/Prep Replacement Cart. -- 79278	The PRP-h5 utilizes the PRP-3 as its base with a pentafluorinated modification, making it more hydrophobic in nature. The PRP-h5, with its functionality derived from a pentafluorinated polymer bead, delivers...
PRP-X400 7 µm 2.1 x 250 mm -- 79398 PRP-X400 7 µm 4.1 x 150 mm -- 79717 PRP-X400 7 µm 4.1 x 250 mm -- 79473 PRP-X400 7 µm 4.6 x 250 mm PEEK -- 79387 PRP-X400 Analytical Replacement Cart. -- 79377 PRP-X400 Analytical Starter Kit -- 79376 PRP-X400 Semiprep/Preparative -- 79132 PRP-X400 Semiprep/Preparative Kit -- 79131	The PRP-X400 column provides a fast separation for glyphosate and its metabolites. The exchange capacity of the PRP-X400 is greater than that of the PRP-X200, leading to characteristics better suited...
PRP-X800 7 µm 4.1 x 150 mm -- 79855 PRP-X800 7 µm 4.1 x 250 mm -- 79828 PRP-X800 Analytical Replacement Cart. -- 79832 PRP-X800 Analytical Replacement Cart. -- 79833 PRP-X800 Analytical Starter Kit -- 79830 PRP-X800 Analytical Starter Kit -- 79831	The PRP-X800 is a polymeric cation exchange column functionalized with itaconic acid that performs the isocratic separation of mono and divalent cations such as lithium, sodium, ammonium, potassium, magnesium and...

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