The Hamilton PRP-C18 Analytical Guard Column Starter Kit (79685) includes one stainless steel holder and two replacement cartridges designed for use with PRP-C18 HPLC columns. It is compatible with the rugged PRP-C18 stationary phase, which provides high-efficiency reversed-phase separations across a pH range of 1-13 and temperatures exceeding 100°C without degradation. The guard column protects analytical columns from contamination and extends their operational life under aggressive mobile phase conditions, including exposure to 1 M NaOH or H2SO4. It is intended for use in high-throughput applications in pharmaceutical, clinical, and life sciences industries.
The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase has excellent mechanical and thermal stability (> 100°C), does not shrink or swell, and is completely inert to most conditions commonly encountered in reversed-phase chromatography.
The PRP-C18 is a durable and effective column for general purpose HPLC and especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries.
Oligonucleotide Purification
The properties of the PRP-C18 make it a superior column in the field of oligonucleotide purifications, providing:
Applications:
Organic compounds: small molecules (< 2,000 mw), pharmaceuticals, steroids, halides, vitamins, amino acid analysis, herbicides
Examples of analytes that can be separated on PRP-C18 columns:
| Hamilton Company | |
|---|---|
| Product Category | HPLC Columns |
| Product Number | 79685 |
| Product Name | PRP-C18, Analytical Guard Column Starter Kit (1 holder, 2 cartridges), Stainless Steel |
| Column Type | Guard |
| Stationary Phase/Separation Process | Reversed Phase |
| Construction Material | Stainless Steel |
| Packing Diameter | 12 µm (0.4724 mils) |
| Pore Diameter | 0.0100 µm (3.94E-4 mils) |
