The Hamilton PRP-C18 analytical guard column replacement cartridges (5/pk), stainless steel, are designed for use with PRP-C18 reversed-phase HPLC columns to protect analytical columns from contaminants. These cartridges are compatible with the same high-pH and high-temperature conditions as the main column, maintaining stability up to 100°C and in mobile phases ranging from pH 1 to 13. They feature the same rigid, non-shrinking, non-swelling stationary phase that resists stripping or bleeding under aggressive regeneration conditions, enhancing column life and method flexibility without degradation. Each cartridge is a direct replacement for the analytical guard column holder and is intended for use in clinical, pharmaceutical, environmental, food, forensics, and life science applications.
The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase has excellent mechanical and thermal stability (> 100°C), does not shrink or swell, and is completely inert to most conditions commonly encountered in reversed-phase chromatography.
The PRP-C18 is a durable and effective column for general purpose HPLC and especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries.
Oligonucleotide Purification
The properties of the PRP-C18 make it a superior column in the field of oligonucleotide purifications, providing:
Applications:
Organic compounds: small molecules (< 2,000 mw), pharmaceuticals, steroids, halides, vitamins, amino acid analysis, herbicides
Examples of analytes that can be separated on PRP-C18 columns:
| Hamilton Company | |
|---|---|
| Product Category | HPLC Columns |
| Product Number | 79686 |
| Product Name | PRP-C18, Analytical Guard Column Replacement Cartridges (5/pk), Stainless Steel |
| Column Type | Guard |
| Stationary Phase/Separation Process | Reversed Phase |
| Construction Material | Stainless Steel |
| Packing Diameter | 12 µm (0.4724 mils) |
| Pore Diameter | 0.0100 µm (3.94E-4 mils) |
