Ventana Medical Systems, Inc. Datasheets for Organic Chemicals

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Product Name Notes
α-1-Antichymotrypsin Primary Antibody reacts with histiocytes and histiocytic neoplasms. Its major application is defining the presence of α-1-Antichymotrypsin in histiocytes and tumors derived from them. In eosinophilic granuloma and malignant...
α-1-Antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for α-1-Antitrypsin may also be...
Helicobacter pylori is a gram negative bacterium that has been shown to be the causative organism in some gastric and duodenal ulcers. It is the most common cause of antral...
ultraView Universal DAB is a multimer-technology based detection system intended for the specific and sensitive detection of mouse and rabbit primary antibodies. The kit is biotin-free, thus it eliminates...
A modified Gill's hematoxylin intended for staining cellular nuclei on slides containing cells from frozen tissue, formalin fixed and paraffin embedded tissue, or cytologic preparations. For use on NexES IHC...
A modified Mayer's hematoxylin intended for staining cellular nuclei on slides containing cells from frozen tissue, formalin-fixed and paraffin-embedded tissue, or cytologic preparations. For use on NexES IHC and BenchMark...
According to the World Health Organization classification system, the major diagnostic criterion for bone marrow involvement by systemicmastocytosis (SM) is the presence of dense aggregates (>15 cells) of mast cells.
ACTH is a useful marker in classification of pituitary tumors. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g., some small cell carcinomas of the...
Actin is a major component of the cytoskeleton and is present in every cell type. Actin can be resolved on the basis of its isoelectric points into three distinctive components:...
Actin is a major component of the cytoskeleton. This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for Myoepithelium.
AFB III Staining Kit is used to selectively demonstrate Mycobacterium and other acid fast organisms and components in tissue. AFB III Staining Kit is a modification of the Ziehl-Neelsen stain.
Alcian Blue for PAS is an accessory reagent that is used with the PAS Staining Kit. In conjunction with the PAS Staining Kit, Acid mucin stains bright blue, while neutral...
Alcian Blue Staining Kit demonstrates weakly acidic mucopolysaccharides. At pH 2.5, Alcian Blue stains sulfated mucins, usually epithelial in origin (and usually PAS-negative), with some occurrences in connective tissue, e.g.
Androgen Receptor (SP107) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test...
Annexin (ANXA1) is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97% of samples from patients with hairy cell leukemia. By contrast, B-cell...
Anti-H. pylori antibody reacts with a spiral bacillus bacteria located on the surface of the pyloric and stomach mucosa. Studies have shown that H. pylori plays an important role...
Anti-Actin, Muscle (HUC 1-1) may be used to aid in the identification of cells of normal and abnormal myocytic lineage as an aid in diagnosis of anaplastic tumors. Anti-Actin, Muscle...
Anti-BCA-225 antibody recognizes a human breast carcinoma associated glycoprotein BCA-225 (220-225 kD). This protein differs in size and distribution from other breast carcinoma antigens. Unlike other antibodies against breast carcinoma...
Anti-bcl-2 (SP66) Rabbit Monoclonal Primary Antibody is directed against human bcl-2 expressed by B-cells of the mantle zone and interfollicular T cells. This antibody exhibits a cytoplasmic staining pattern and...
Anti-bcl-6 is a transcriptional regulator gene which codes for a 706-amino acid nuclear zinc finger protein. Antibodies to this protein stain the germinal center cells in lymphoidfollicles, the follicular and...
Anti-c-MYC (Y69) Rabbit Monoclonal Primary Antibody (anti-c-MYC (Y69)) is directed against the transcription factor c-MYC, an important factor in cell cycle regulation. The anti-c-MYC (Y69) antibody exhibits a nuclear staining...
Anti-Caldesmon is a regulatory protein found in smooth muscle and other tissues which interacts with actin, myosin, tropomyosin, and calmodulin. Anti-Caldesmon antibody labels smooth muscle and tumors of smooth muscle,...
Anti-CD138/syndecan- 1 is a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas. Various forms of Hodgkin's disease have also shown positive staining with this antibody.
Anti-CD19 is directed against the CD19 protein. This antibody may be used to detect the CD19 standard and variant proteins in the vast majority of B cell lymphomas including follicular...
Anti-CD22 is directed against the type 1 integral membrane glycoprotein, CD22. Anti-CD22 (SP104) exhibits a cell membranous and/ or cytoplasmic staining pattern and may be used to aid in the...
Anti-CD44 (SP37) Rabbit Monoclonal Primary Antibody is directed against the CD44 protein. CD44 is a type I transmembrane receptor protein expressed in several cell types including T and B lymphocytes,...
Anti-CD57 antibody marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. NK-1 also stains neuroendocrine...
Anti-CD61 labels the IIIa subunit of the non-covalently linked glycoprotein heterodimer IIb/IIIa complex present on human platelets and their precursors. This antibody is useful in identifying megakaryoblastic differentiation as seen...
Anti-CD7 (SP94) Rabbit Monoclonal Primary Antibody is directed against the 40kD transmembrane glycoprotein, CD7 which is present in thymocytes and mature T cells. Anti-CD7 (SP94) may be used to aid...
Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas but rarely T-cell lymphomas. It stains the cell membrane but a paranuclear globular labeling is also noted. It is a useful...
Anti-Chromogranin A (LK2H10) specifically binds to the chromogranin A protein located in the secretory granules of normal and neoplastic neuroendocrine cells. Chromogranin A is also expressed by adrenal (medulla), parathyroid,...
Anti-Cytokeratin (CAM 5.2) Mouse Monoclonal Primary Antibody is directed against cytokeratin 7 and cytokeratin 8 present on secretory epithelia but not on stratified squamous epithelia. This antibody may be used...
Anti-Cytokeratin 10 (SP99) Rabbit Monoclonal Primary Antibody is directed against the 56.5kD member of the type 1 cytokeratin family, cytokeratin 10. Cytokeratin 10 is expressed in keratinizing stratified epithelia, but...
Anti-Cytokeratin 17 (SP95) Rabbit Monoclonal Primary Antibody is directed against Cytokeratin 17 expressed in basal cells of complex epithelia, glandular epithelium with myoepithelial component, and transitional and pseudostratified epithelia. This...
Anti-Cytokeratin 19 reacts with a wide variety of epithelium and epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is...
Anti-Cytokeratin 5/6 (D5/16B4) Mouse Monoclonal Primary Antibody detects cytokeratins 5 and 6. Cytokeratin 5 is expressed in various epithelia and mesothelial cells, while cytokeratin 6 is expressed by proliferating squamous...
Anti-Cytokeratin 8 & 18 (B22.1 & B23.1) Primary Antibody is a cocktail of two mouse monoclonal antibodies. Cytokeratins 8 & 18 can be found in most simple epithelium, e.g. thyroid,...
Anti-Epithelial Related Antigen (MOC-31) Mouse Monoclonal Primary Antibody is directed against the 40kD epithelial cell adhesion molecule, Epithelial Related Antigen. Epithelial Related Antigen is expressed in most normal epithelial cells...
Anti-ERG (EPR3864) Rabbit Monoclonal Primary Antibody (anti-ERG (EPR3864)) is directed against the C-terminus of the ETS transcription regulator, ERG, and is capable of detecting both wildtype ERG, and truncated ERG...
Anti-Factor VIII-Related Antigen antibody reacts with endothelial cells and neoplastic blood cells. This antibody has helped to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma...
Anti-Fascin is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells...
Anti-FDC is useful in the identification of follicular dendriditic cell matrix found in normal lymph nodes and tonsilar tissue. This antibody has been found to label cells in approximately 60%...
Anti-Follicle Stimulating Hormone (FSH) is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with FSH-producing cells (gonadotrophs).
Anti-Gastrin antibody gives positive staining of G cells of human antral/pyloric mucosa and cells producing gastrin or a structural gastrin analogue as is seen in stomach; nostaining of other cells...
Anti-GFAP antibody detects astrocytes, Schwann cells, satellite cells, enteric glial cells, and some groups of ependymal cells. This marker is mainly used to distinguish neoplasms of astrocytic origin from other...
Anti-Glucagon antibody detects glucagon-secreting cells and tumors such as glucagonomas. Studies show that approximately 80% of glucagonomas are malignant and these patients have a syndrome often initially recognized by dermatologists.
Anti-Glypican 3 (GC33) Mouse Monoclonal Primary Antibody is directed against the heparan sulfate proteoglycan, glypican 3. This antibody may be used to aid in the differentiation of hepatocellular carcinoma from...
Anti-Growth Hormone is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly). It reacts with GH-producing cells.
Anti-HBME-1 has been demonstrated to label mesothelial cells, both benign and malignant(malignant mesothelioma) and thus has been used in distinguishing mesothelioma fromadenocarcinomas of various origins. More recently this antibody has...
Anti-Hepatocyte Specific Antigen (OCH1E5) Primary Antibody is a mouse monoclonal antibody that recognizes both benign and malignant liver including such tumors as hepatoblastoma, hepatocellular carcinoma, and hepatic adenoma. It recognizes...
Anti-IgA antibody reacts with surface immunoglobulin IgA alpha chains. It is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived Hodgkin's lymphomas. Due to the restricted expression of heavy and...
Anti-IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived lymphomas (in particular marginal zone lymphoma). Cytoplasmic staining is...
Anti-IgG antibody reacts with surface immunoglobulin IgG gamma chains. This antibody is useful when identifying leukemias, plasmacytomas, and B-cell lineage derived Hodgkin's lymphomas. Due to the restricted expression of heavy...
Anti-IgM antibody reacts with surface immunoglobulin IgM mu chains. IgM is one of the predominant surface immunoglobulins on B lymphocytes. This antibody is useful when identifying lymphomas, plasmacytomas, and B-cell...
Anti-Inhibin alpha is an antibody against a peptide hormone which has demonstrated utility in the differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the...
Anti-Leukocyte Common Antigen (Anti-LCA) monoclonal antibody is routinely used to aid in the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphomais suspected by the morphological or clinical data. It is...
Anti-Luteinizing Hormone (LH) is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with LH-producing cells (gonadotrophs).
Anti-Lysozyme stains myeloid cells, histiocytes, granulocytes, macrophages, and monocytesin human tonsil, colon, and skin. It is an important marker that may demonstrate the myeloidor monocytic nature of acute leukemia. The...
Anti-Macrophage reacts with tingible macrophages, interdigitating macrophages of lymph nodes and tissue macrophages, e.g. Kupffer cells of the liver and alveolar macrophages of the lung. The antibody also stains a...
Anti-MLH-1 (M1) Mouse Monoclonal Primary Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MLH1, expressed in the nucleus of normal proliferating cells. Deficient or low levels...
Anti-MUC1 (H23) is directed against the membrane bound, glycosylated phosphoprotein MUC1. This antibody may be used to aid in the identification of normal and neoplastic MUC1 expressing cells.
Anti-Myeloperoxidase detects granulocytes and monocytes in blood and precursors of granulocytes in the bone marrow. This antibody can detect myeloid cell populations of the bone marrow as well as in...
Anti-Myogenin labels the nuclei of myoblasts in developing muscle tissue and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilm's tumor.
Anti-Neurofilament antibody stains an antigen localized in a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastoma s, and neuroblastomas stain positively for neurofilament. Neurofilaments are also present...
Anti-p53 (Bp53-11) is directed against both the mutant and wild type of the p53 nuclear phosphoprotein. Very rare normal cells express p53, but alterations in the p53 suppressor gene result...
Anti-p57Kip2 (Kp10) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
Anti-Pan Cytokeratin (AE1/AE3/PCK26) may be used to aid in the identification of normal and abnormal epithelial cells and to determine the lineage of poorly differentiated malignant tumors. This antibody cocktail...
Anti-PLAP antibody immunoreacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to...
Anti-Prolactin is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with prolactin-producing cells. Such prolactin-producing cells can also be found in prostate...
Anti-PSAP reacts with prostatic acid phosphatase in the glandular epithelium of normal and hyperplastic prostate, carcinoma of the prostate, and metastatic cells of prostatic carcinoma. This marker may be helpful...
Anti-PTH antibody is useful to distinguish parathyroid hyperplasia/neoplasm s from thyroid and metastatic neoplasms; although the pathologist is typically aware of the preoperative hypercalcemic status. Occasionally when the surgeon does...
Anti-Somatostatin is a useful marker of D cells of pancreatic islet cells. D-cell identification can be used to identify hyperplasia of the pancreatic islets as well as islet cell tumors...
Anti-Synaptophysin is useful in the detection of normal neuroendocrine cells and neuroendocrine neoplasms. Reactive neoplasms of neural type include neuroblastomas, ganglio neuroblastomas, ganglio neuromas, pheochromocytomas, chromaffin and nonchromaffin paragangliomas. The...
Anti-TAG-72 recognizes a high molecular weight glycoprotein called TAG-72 that is presentin human adenocarcinomas and in lesser amounts, non-neoplastic tissues. It has also been found to be useful to distinguish...
Anti-Terminal Deoxynucleotidyl Transferase (TdT) antibody labels normal cortical thymocytes and primitive lymphocytes. Anti-TdT antibody detects an enzyme found in the nucleus of normal hematopoietic cells, normal cortical thymocytes and in...
Anti-Thyroglobulin antibody reacts with human thyroglobulin as demonstrated by a single band of immunoblotting in a lysate of human thyroid tissue. The vast majority offollicular carcinomas of the thyroid will...
Anti-Thyroid Stimulating Hormone (TSH) is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with TSH-producing cells (thyrotrophs). TSH is a pituitary hormone...
Antibodies against CD15 normally react in a strong cell surface membrane staining pattern with granulocytes and granulocyte precursors, monocytes, a subset of tissue macrophages, and activated T lymphocytes. CONFIRM anti-CD15...
Basic AEC Detection Kit is an indirect biotin streptavidin system for detecting mouse and rabbit primary antibodies. The kit is intended for use with formalin-fixed, paraffin-embedded tissue or frozen tissue.
Beta-catenin is a 92 kD protein normally found in the cytoplasm of the cell in the submembranous location. This protein is associated with E-Cadherin and may be essential for the...
Blood group antigens have been examined as potential discriminators between pulmonary adenocarcinoma (PACA) and epithelioid mesotheloma (EM). Lewisy is the only one of these that appears to have some merit.
BOB.1 (SP92) used as an aid in the identification of B-cells in germinal centers, mantle cells, and differentiation of lymphomas within the context of an antibody panel, the patient’s clinical...
C4d is a stable split product remnant of classical complement activation which becomes covalently bound to endothelium and basement membrane, after induction of the classical antibody-induced pathway. As an established...
CA 19-9 antigen is highly expressed in gastrointestinal (gastric, pancreatic, and colonic) adenocarcinomas and salivary gland mucoepidermoid carcinomas. Anti-CA 19-9 antibody is usually not reactive with breast, kidney, and prostate...
CA-125 reacts with malignant ovarian epithelial cells. The antigen is formalin resistant permitting the detection of ovarian cancer by immunohistochemistry , although serum assays for this protein are widely used...
Calponin is a 34 kD polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth muscle contraction mechanism and is restricted exclusively to smooth muscle tissue. Anti-calponin...
CD14 is a surface protein preferentially expressed on monocytes/macrophage s. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Anti-CD14 antibody labels Kupffer cells in...
CD163 was recently identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobinhemoglobi n complexes. This receptor is expressed on the surface of monocytes...
CD1a, a protein of 43 to 49 kD, has been shown to be expressed on dendritic cells and cortical thymocytes. Langerhans cells in the skin and some epithelia also express...
CD2 is one of the earliest T cell lineage restricted antigens to appear during T cell differentiation and only a rare CD2+ cell can be found in the bone marrow.
CD21 antigen is an integral membrane glycoprotein of molecular weight 140 kD. Anti-CD21 is useful in the identification of follicular dendriditic cell matrix found in normal lymph nodes and tonsillar...
CD21 antigen is an integral membrane glycoprotein of molecular weight 145 kD. Anti-CD21 is useful in the identification of follicular dendriditic cell matrix found in normally lymph nodes and tonsillar...
CD30 antigen is expressed in mononuclear Hodgkin's cells and multinucleated Reed Sternberg cells of Hodgkin's lymphoma as well as on anaplastic large cell lymphomas. This antibody variably produces membranous, cytoplasmic...
CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation.
CD34 is selectively expressed on human lymphoid and myeloid hematopoietic progenitor cells. The antigen is also expressed on vascular endothelium. CD34 antibody is of value for the identification of vascular...
CD43 (also known as leucosialin or sialophorin) is a glycoprotein antigen expressed on the membrane and in the cytoplasm of T cells, cells of myeloid origin and some B cells.
CD45, LCA is expressed on the cytoplasmic membrane of T and B lymphocytes, monocytes, macrophages, mast cells, and weakly on granulocytes. CONFIRM anti-CD45, LCA (RP2/18) is directed against the CD45RB...
CD45R antibody stains preferentially B cells and their neoplasms but is less specific as it will also react with some T-cell lymphomas and non-lymphoid tumors. The antigen for this antibody...
CD56 (MRQ-42) used as an aid in the identification of neural/neurodendocri ne tissues, natural killer (NK) cells, NK-like T-cells, and diagnosis of related neoplasms within the context of an antibody...
CDX-2 is a caudal-related homeobox transcription factor whose expression in the adult is normally restricted to the intestinal epithelium. It is implicated in the development and maintenance of the intestinal...
CEA (CEA31) used as an aid in the identification and diagnosis of adenocarcinomas within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by...
CEA (TF 3H8-1) Primary Antibody may be used to aid in the identification of cells of normal and abnormal epithelial lineage as an aid in diagnosis of anaplastic tumors. CEA...
Collagen Type IV is the major component of the basal lamina, so antibodies to this molecule confirm its presence and reveal the morphological appearance of the structure. Normal tissue stains...
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. C3d deposition in the renal...
CONFIRM anti CD4 (SP35) Rabbit Monoclonal Primary Antibody is intended for the qualitative detection of CD4 in sections of formalin-fixed, paraffin-embedded normal and neoplastic human tissues. CD4 is present on...
CONFIRM anti-ALK1 (ALK01) recognizes a formalin resistant epitope in both the p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) protein and the nucleophosmin (NPM) protein and...
CONFIRM anti-bcl-2 (124) Mouse Monoclonal Primary Antibody is directed against human bcl-2 expressed by B cells of the mantle zone and interfollicular T cells. This antibody exhibits a cytoplasmic staining...
CONFIRM anti-Calretinin (SP65) Rabbit Monoclonal Primary Antibody is directed against the calcium binding protein, calretinin, expressed by normal and reactive mesothelium, eccrine glands of skin, Sertoli cells of the testis,...
CONFIRM anti-CD20 (L26) specifically binds to antigens located in the plasma membrane and cytoplasmic regions of normal B lymphocytes and may also be expressed in Reed-Sternberg cells. This phosphoprotein is...
CONFIRM anti-CD3 (2GV6) Primary Antibody is a rabbit monoclonal antibody (IgG) directed against the nonglycosylated epsilon chain of the human CD3 molecule. CD3 is expressed in the membrane and cytoplasm...
CONFIRM anti-CD45RO (UCHL-1) reacts predominantly with the p180 component of the Leukocyte Common Antigen (LCA) antigen family and weakly with the 190 kD and 205 kD isoforms. This reagent reacts...
CONFIRM anti-CD5 (SP19) Rabbit Monoclonal Primary Antibody is directed against human CD5 expressed on the plasma membrane of virtually all human T cells and the B1a subset of human B...
CONFIRM anti-CD56 (123C3) Mouse Monoclonal Primary Antibody is directed against the CD56 molecule or neural cell adhesion molecule expressed by most neuroectodermally derived cell lines, tissues and neoplasms. It is...
CONFIRM anti-CD68 reacts with a 110 kD intracellular glycoprotein associated with the cell membrane of macrophages and some myeloid elements.
CONFIRM anti-CD79a (SP18) Rabbit Monoclonal Primary Antibody is intended for the detection of CD79a in normal and neoplastic human tissues. Anti-CD79a is directed against a protein expressed on the surface...
CONFIRM anti-CD8 (SP57) Rabbit Monoclonal Primary Antibody is intended for the qualitative detection of CD8 in sections of normal and neoplastic human tissues. The CD8 glycoprotein is present on cytotoxic/suppressor...
CONFIRM anti-CD99 (O13) Mouse Monoclonal Primary Antibody is directed against human CD99 expressed on T lymphocytes, cortical thymocytes, granulosa cells of the ovary, pancreatic islet cells, CNS ependymal cells and...
CONFIRM anti-Cytokeratin (34βE12) Mouse Monoclonal Primary Antibody recognizes cytokeratins 1, 5, 10, and 14 of the Moll catalog and is used as an aid in the identification of basal cells...
CONFIRM anti-Cytokeratin (AE1) may be used to aid in the identification of cells of normal and abnormal epithelial lineage as an aid in diagnosis of anaplastic tumors. CONFIRM anti-Cytokeratin (AE1)...
CONFIRM anti-Cytokeratin 20 (SP33) Rabbit Monoclonal Primary Antibody is directed against a type I cytokeratin protein of mature enterocytes and goblet cells of the gastric and intestinal mucosa. This antibody...
CONFIRM anti-Cytokeratin 7 (SP52) Rabbit Monoclonal Primary Antibody is directed against a type II cytokeratin protein expressed by most ductal, glandular and transition alepithelia. Cytokeratin 7 exhibits a cytoplasmic localization.
CONFIRM anti-Desmin (DE-R-11) identifies normal muscle cells and myogenic neoplasms bearing the desmin antigen. The most obvious application of anti-desmin antibodies is in the characterization of myogenic neoplasms or in...
CONFIRM anti-EGFR (5B7) is a rabbit monoclonal antibody produced against a synthetic peptide from the carboxy terminal (cytoplasmic) region of EGFR. The epitope recognized by anti-EGFR (5B7) is associated with...
CONFIRM anti-EMA (E29) Mouse Monoclonal Primary Antibody is directed against epithelial membrane antigen expressed on the apical surface of glandular epithelia. This glycoprotein is primarily membrane localized on normal and...
CONFIRM anti-Epidermal Growth Factor Receptor (EGFR) (3C6) Primary Antibody is directed against the extracellular domain of human EGFR, a protein of 170 kD. The antibody also recognizes the type III...
CONFIRM anti-Estrogen Receptor (ER) (SP1) Primary Antibody is a rabbit monoclonal antibody (IgG) that is intended for laboratory use for the qualitative detection of estrogen receptor (ER) antigen in sections...
CONFIRM anti-IGF-1R (G11) is a rabbit monoclonal antibody produced against a synthetic peptide from the internal domain of the beta chain receptor near the carboxy terminal region and binds to...
CONFIRM anti-Kappa (polyclonal) specifically binds to antigens located in the cell membrane and cytoplasmic regions of normal B cells and plasma cells. Kappa light chains are polypeptide chains which in...
CONFIRM anti-Keratin (AE3) recognizes basic cytokeratins of 65-67, 64, 59, 56, and 52 kD. The antibody is a marker used to distinguish carcinomas from non epithelial tumors.
CONFIRM anti-Ki-67 (30-9) Primary Antibody is directed against C-terminal portion of Ki-67 antigen. Staining for Ki-67 can aid in assessing the proliferative activity of normal and neoplastic tissue. This antibody...
CONFIRM anti-Lambda specifically binds to antigens located in the cell membrane and cytoplasmic regions of normal B cells and plasma cells. Lambda light chains are polypeptide chains which in combination...
CONFIRM anti-LMO2 (1A9-1) is a mouse IgG1 monoclonal antibody and is directed against a 24 kD protein in the LIM only family. LMO2 is expressed in normal germinal center (GC)...
CONFIRM anti-Melanosome (HMB45) has been shown to react with immature melanosomes in fetal and neonatal melanocytes and infantile retinal pigment epithelium. It does not react with normal resting adult melanocytes,...
CONFIRM anti-MITF (C5/D5) Mouse Monoclonal Primary Antibody is a mouse monoclonal cocktail. This antibody cocktail reagent detects microphthalmia transcription factor (MITF) proteins 52-56 KD of MITF expressing cells in normal...
CONFIRM anti-MSH6 (44) Mouse Monoclonal Antibody is used to qualitatively identify human DNA mismatch repair (MMR) protein MSH6, expressed in the nucleus of normal proliferating cells. Deficient or low levels...
CONFIRM anti-PAX5 (SP34) Rabbit Monoclonal Primary Antibody is directed against a nuclear epitope present in human B lymphocytes. This antibody may be used to aid in the identification of normal...
CONFIRM anti-PR (1E2) Primary Antibody is intended for laboratory use for the qualitative detection of progesterone receptor(PR) antigen in sections of formalin-fixed, paraffin-embedded tissue on a Ventana automated slide stainer...
CONFIRM anti-Prostate Specific Antigen (PSA) is directed against both free and bound human prostate specific antigen (PSA). PSA is a 33-34 kD chymotrypsin like serine protease (kallikrein family) specifically expressed...
CONFIRM anti-Thymidine Phosphorylase (P-GF.44C) Mouse Monoclonal Primary Antibody recognizes human thymidine phosphorylase, an angiogenic factor, expressed in varying levels by macrophages, stromal cells, glial cells and some epithelial cells. Thymidine...
CONFIRM anti-Topoisomerase II (JS5B4) Rabbit Monoclonal Primary Antibody is designed to qualitatively detect the presence of topoisomerase II expressing cells. During the cell cycle, topoisomerase II is expressed in the...
CONFIRM anti-Total c-MET (SP44) Rabbit Monoclonal Primary Antibody is directed against a membranous and/or cytoplasmic epitope present in human normal epithelial or tumor cells. This antibody may be used to...
Congo Red Staining Kit is used to selectively demonstrate Amyloid in tissue sections. The staining reaction is based on the application of congo red which stains the patterns of atypical...
Cyclooxygenase 2 (COX-2) catalyzes the conversion of arachidonic acid to prostaglandin H2 in the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. COX-2 inhibition by nonsteroidal antiinflamatory agents...
Cytokeratin 14 is a 50 kD polypeptide found in basal cell of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-Cytokeratin 14 has been demonstrated to be useful in...
Cytokeratin 8 is reactive with the majority of epithelium and epithelial tumors; nonsquamous tumors stain positive and squamous tumors stain negative. This antibody stains positive for adenocarcinomas of the breast,...
Diastase is an enzyme which selectively digests (breaks down) glycogen. It is used to remove glycogen from tissue. This produces "negative PAS" staining of the glycogen. Any remaining PAS staining...
DOG1 is used as an aid in the identification and diagnosis of gastrointestinal stromal tumors (GIST) within the context of an antibody panel, the patient’s clinical history, and other diagnostic...
E-Cadherin is an adhesion protein that is expressed in cells of epithelial lineage. Anti-E Cadherin stains positively in glandular epithelium as well as adenocarcinomas of the lung, G.I. tract, and...
Elastic Staining Kit demonstrates elastic fibers in tissue sections. Elastic Staining Kit is a modification of Hart's method for elastic fibers. A resorcin-fuchsin solution is used to stain elastic fibers...
Enhanced Alkaline Phosphatase Red Detection kit is an indirect biotin streptavidin system for detecting mouse and rabbit primary antibodies. The Fast Red chromogen produces a red precipitate that is readily...
Ep-CAM consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in...
Expression of CD23 has been detected in neoplastic cells from cases of B-cell chronic lymphocytic leukemias and B-cell small lymphocytic lymphomas. Some hairy cell leukemias and diffuse large B-cell lymphomas...
Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present...
Factor XIIIa is a blood proenzyme that has been identified in platelets,; megakaryocyte, and fibroblastlike mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present...
FITC anti-Albumin Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human albumin. This reagent should be used in conjunction with a panel of...
FITC anti-C1q (complement 1q) Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human C1q. This reagent should be used in conjunction with a...
FITC anti-C3 (complement 3) Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human C3. This reagent should be used in conjunction with a...
FITC anti-C4 (complement 4) Primary Antibody is a sheep derived polyclonal antibody labeled with fluorescein and specificallydirected against human C4. This reagent should be used in conjunction with a panel...
FITC anti-Fibrinogen Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human fibrinogen. This reagent should be used in conjunction with a panel of...
FITC anti-IgA (immunoglobulin A) Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human IgA. This reagent should be used in conjunction with a...
FITC anti-IgG (immunoglobulin G) Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human IgG. This reagent should be used in conjunction with a...
FITC anti-IgM (immunoglobulin M) Primary Antibody is a goat derived polyclonal antibody labeled with flurescein and specifically directed against human IgM. This reagent should be used in conjuction with a...
FITC anti-Kappa Primary Antibody is a goat derived polyclonal antibody labeled with fluorescein and specifically directed against human kappa immunoglobulin light chains. This reagent should be used in conjunction with...
FITC anti-Lambda Primary Antibody is a burro derived polyclonal antibody labeled with fluorescein and specifically directed against human lambda light chains. This reagent should be used in conjunction with a...
Galectin-3 is a 31 kD beta-galactosidase binding lectin. It has been associated with binding to the basement membrane glycoprotein laminin. Anti-Galectin-3 has been demonstrated to be valuable in differentiating between...
GCDFP-15 is a 15,000-dalton glycoprotein which is localized in the apocrine metaplastic epithelium lining breast cysts and in apocrine glands in the axilla, vulva, eyelid, and ear canal. Approximately 70%...
Giemsa Staining Kit differentiates leukocytes in bone marrow and other hematopoietic tissue (lymph nodes). The stain can also be used to demonstrate some microorganisms, such as H. pylori. A...
Glucose transporter type I (GLUT1), a prototype member of GLUT super family, reacts with a 55 kD protein, is a membrane-associated erythrocyte glucose transport protein. It is a major glucose...
Glycophorin A is a sialoglycoprotein present on human red blood cells and their precursors. Anti-Glycophorin A has been used to characterize erythroid cell development and in the diagnosis of erythroid...
Glypican-3 (GPC3) is a glycosylphosphatidyl inositol-anchored membrane protein, which may also be found in a secreted form. Recently, GPC3 was identified as a useful tumor marker for the diagnosis of...
GMS II Staining Kit selectively demonstrates polysaccharides in the cell walls of fungi and other opportunistic organisms, such as Pneumocystis carinii. GMS Staining Kit is a modification of Gomori's...
Granzymes are serine proteases which are stored in specialized lytic granules of cytotoxic T lymphocytes and in natural killer cells. Anti-Granzyme B has been useful in diagnosing natural killer/T-cell lymphoma...
HGAL used as an aid in the identification of follicular lymphoma within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified...
Human chorionic gonadotropin (hCG) is a protein secreted in large quantities by normal trophoblasts; the antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and...
Human herpes virus type 8 (HHV-8) is the likely etiological agent of Kaposi's sarcoma (KS). HHV-8 DNA sequences have been found in Kaposi's sarcoma lesions, primary effusion lymphoma, and multicentric...
Human placental lactogen (hPL), also previously known as "human chorionic somatomammotropin", is a 22 kD protein with partial homology to growth hormone. hPL is first detectable in the maternal serum...
IgG4 (MRQ-44) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
Immunohistochemical staining with Anti-Calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies...
Immunostaining with anti-Myoglobin is useful for the identification of tumors of muscle origin. Since myoglobin is found exclusively in skeletal and cardiac muscle and is not present in any other...
INI-1 (MRQ-27) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
Insulin is produced in the beta cells of the pancreas. The presence of insulin in the cytoplasm of islet tumors is the most reliable indication of functional insulinomas. Defective insulin...
Iron Staining Kit detects the presence of ferric iron in tissue. The iron is separated from protein by hydrochloric acid. The free ferric iron reacts with the potassium ferrocyanide to...
iVIEW DAB Detection Kit is an indirect biotin streptavidin system for detecting mouse and rabbit primary antibodies. The DAB chromogen produces a dark brown precipitate that is readily visualized by...
Jones Light Green Kit demonstrates capillary basement membrane in formalin-fixed paraffin embedded tissue. Jones Light Green Kit is a modification of Jones Methanamine Silver procedure. Methanamine in this stain is...
Jones Staining Kit demonstrates capillary basement membrane and is a modification of Jones Methanamine Silver procedure. Methanamine in this stain is used to demonstrate the carbohydrate component of basement membrane.
Kidney-specific cadherin (KSP-Cadherin) is a novel, kidney-specific member of the cadherin family of cell adhesion molecules. Within the kidney, KSP-Cadherin is found exclusively in the basolateral membrane of renal tubular...
Light Green for PAS is an accessory reagent that is used with the PAS Staining Kit. In conjunction with the PAS Staining Kit, fungal elements stain magenta against a light...
MBP is present in the central and peripheral nervous system, the antibody reacts with soft tissue tumors. MBP has been demonstrated in neuromas, neurofibromas, and neurogenic sarcomas; other spindle cell...
Melanoma is a malignant tumor deriving from melanocytes. Melanocytes are derivative cells originating from the neuroectodermal crest, which migrate during the early fetal period into the skin, where they settle...
Melanoma Triple Cocktail (HMB45+A103+T311) is an antibody cocktail of anti-Melanosome (HMB45), anti-MART-1/melan A (A103), and anti-Tyrosinase (T311) mouse monoclonal antibodies. This antibody cocktail demonstrates cytoplamic staining and may be used...
Microsatellite instability (MSI) is characterised by genome-wide alterations in short, repetitive DNA sequences. It is caused by defects in the nucleotide mismatch repair (MMR) system. Biologically, defective MMR results in...
MLH1 is a mismatch repair gene that is deficient in a high proportion of patients with microsatellite instability (MSI-H). This finding is associated with the autosomal dominant condition known as...
MSH2 is a mismatch repair gene which is deficient in a high proportion of patients with microsatellite instability (MSI-H). This finding is associated with the autosomal dominant condition known as...
Mucicarmine Staining Kit is used to detect acid mucopolysaccharides (mucin). Mucin is a secretion of acid mucopolysaccharides and other substances produced by a variety of epithelial and connective tissue cells.
Mucins are high molecular weight glycoproteins which constitute the major component of the mucus layer that protects the gastric epithelium from chemical and mechanical aggressions. In humans, at least 14...
MUM1 is a 50 kDa protein encoded by MUM1 gene, and a member of the interferon regulatory factor family of transcription factors. MUM1/IRF4 is expressed in the nuclei and cytoplasm...
Napsin is a pepsin-like aspartic proteinase in the A1 clan of the AA clade of proteinases. There are two closely related napsins, napsin A and napsin B. Napsin A is...
Neuron Specific Enolase is present in high concentration in neurons and in central and peripheral neuroendocrine cells, therefore, anti-NSE reacts with cells of neural and neuroendocrine lineage. If neoplastic cells...
NGFR, a 75 kd glycoprotein (also known as P-75NTR), is the first of neurotrophin receptors to be isolated and is a member of the tumor necrosis factor (TNF) receptor family.
Novel anti-melanoma antibody. Studies thus far have shown a similar sensitivity to melanocytic proliferations as that seen with S-100 protein staining, which is somewhat higher than that seen with HMB-45.
Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. These are involved in proliferation and differentiation, and despite...
OCT-4 is a transcription factor that maintains and regulates pluripotency in embryonic stem and germ cells. It has a very high sensitivity and specificity in seminoma/dysgerminom a and embryonal carcinoma...
p21 is a nuclear 21kD protein, a product of the WAF1/CIP1 gene. It is a cyclin-dependent kinase inhibitor 1A (p21, Cip1), also known as CDKN1A, which in humans is encoded...
p27 is a cyclin-dependent kinase inhibitor which regulates progression from G1 to Sphase by binding and inhibitng cyclin-dependent kinases. Low p27 expression has been associated with unfavorable prognosis in renal...
PAS Staining Kit is used to demonstrate the presence of glycogen in tissue. PAS-positive reticular fibers, basement membrane, fungus, and neutral mucopolysaccharides are also detected. PAS Staining Kit may also...
PAX-8 (MRQ-50) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis, the cell death program.
Phosphohistone-H3 is used as an aid in identification of mitotic activity in tumor cells and diagnosis of tumor grade differentiation within the context of an antibody panel, the patient’s clinical...
Podoplanin is a transmembrane mucoprotein (38 kd) recognized by the D2-40 monoclonal antibody. Podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas and in a subset...
Positive staining with anti-AFP antibody is seen in hepatocytes of fetal liver and hepatoma. Since only the traces of AFP are found in adult serum, elevated levels suggest either a...
Programmed death-1 (PD-1) is a member of the CD28 family of receptors that includes CD28, cytotoxic T-lymphocyte-associa ted antigen 4 (CTLA-4), inducible costimulator(ICOS), and Band T-lymphocyte attenuator. These receptors play...
Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl terminal hydrolase-1(UCH-L1), is a 27-kD protein originally isolated from whole brain extracts (1). Although PGP 9.5 expression in normal...
PSA is an antigen present in prostatic tissue and in the majority of prostatic carcinomas. This antibody recognizes primary and metastatic prostatic neoplasms and rarely in tumors of non-prostatic origin.
Renal Cell Carcinoma antibody recognizes a 200 kD glycoprotein localized in the brush border of the proximal renal tubule. This antibody immunoreacts with approximately 90% of primary renal cell carcinomas...
Reticulum II Staining Kit is used to demonstrate reticular fibers. The purpose of this stain is primarily to aid in the differential diagnosis of certain tumor types. In certain tumors,...
S100 was first detected in nervous tissue and has subsequently been found in a number of other cell types including glial and neural cells, Schwann cells, melanocytes and nevus cells,...
S100P (16/f5) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
Smooth Muscle Myosin, heavy chain (SMMS-1) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMMS-1 is also a myoepithelium-associ...
Smoothelin (R4A) is used as an aid in the distinction of terminally differentiated smooth muscle cells, smooth muscle neoplasms of the gastrointestinal tract and other organs, and staging of bladder...
SOX-2 (SP76) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
Spectrin is a cytoskeletal protein which is found in muscles, red blood cells, and red bloodcell precursors. Anti-Spectrin antibody is useful in the diagnosis of erythroid leukemias.
Steiner Staining Kit is used to study tissues to aide in the diagnosis of diseases such as syphilis, some gastric ulcers, (H. pylori), Lyme disease, Legionnaire's disease, Cat...
Synaptophysin is used as an aid in the identification of neuroendocrine neoplasms within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a...
T-bet is used as an aid in the differentiation of hairy cell leukemia, Hodgkin disease, and precursor B-cell lymphoblastic leukemia/lymphoblast ic lymphoma within the context of an antibody panel, the...
TFE3 (MRQ-37) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in sections of formalin-fixed, paraffin-embedded tissue sections using IHC test methods.
The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades. Anti-TRAcP antibody labelsthe cells of hairy cell leukemia (HCL) with...
The wild type p53 molecule has a role in transcription, in cell cycle control, and in many other metabolic functions. It is also a tumor suppressor in that it halts...
This antibody is intended for in vitro diagnostic use. Ventana Medical Systems, Inc's (Ventana) PATHWAY anti-HER-2/neu (4B5)Rabbit Monoclonal Primary Antibody (PATHWAY HER-2 (4B5)) is a rabbit monoclonal antibody intended...
This antibody is intended for in vitro diagnostic (IVD) use. Calcitonin (SP17) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in...
This antibody is intended for in vitro diagnostic (IVD) use. CMV (8B1.2, 1G5.2 & 2D4.2) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of...
This antibody is intended for in vitro diagnostic (IVD) use. LMO2 (SP51) antibody is intended for qualified laboratories to qualitatively identify by light microscopy the presence of associated antigens in...
This antibody reacts with a 53 kDa protein which forms a part of the family of tetraspan moieties. The antigen was originally designated as a lysosomal membrane protein characterized as...
This product is intended for research use only. Not for use in diagnostic procedures. Anti-CMV (8B1.2, 1G5.2 & 2D4.2) may be used as the primary antibody for immunohistochmical staining of...
Trichrome II Staining Kit is used to study connective tissue, muscle and collagen fibers in tissue. Trichrome II Staining Kit is a modification of Masson's Trichrome Stain. Bouin's Solution is...
Trichrome III Blue Staining Kit is used to study connective tissue, muscle and collagen fibers. Trichrome III Blue Staining Kit is a modification of Masson's Trichrome Stain. Bouin's Solution is...
Trichrome III Green Staining Kit is used to study connective tissue, muscle and collagen fibers. Trichrome III Green Staining Kit is a modification of Masson's Trichrome Stain. Bouin's Solution is...
Tryptases constitute a subfamily of trypsin-like proteinases, stored in the mast cell secretory granules and basophils. Upon cellular activation, these enzymes are released into the extracellular environment. Anti-tryptase is a...
TTF-1 is a 38 kD nuclear protein member of the family of homeodomain transcription factors. Exclusive expression in epithelial cells of the thyroid gland and lung allows TTF-1 to be...
Tyrosinase is an enzyme involved in the production of melanin pigments. This enzyme catalyzes the formation of melanin within the cells and thus becomes a useful marker for the presence...
ultraView Universal Red is a multimer-technology based detection system intended for the specific and sensitive detection of mouse and rabbit primary antibodies. The kit is biotin-free, thus it eliminates non-specific...
Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific differentiation products of urothelial cells. In non-neoplastic mammalian urothelium, UPs are expressed in...
VENTANA anti-CD10 (SP67) Rabbit Monoclonal Primary Antibody is directed against the CD10 molecule, or common acute lymphoblastic leukemia antigen (CALLA), expressed on the surface of early lymphoid cells, and on...
VENTANA anti-Cyclin D1 (SP4-R) Rabbit Monoclonal Primary Antibody (VENTANA anti-Cyclin D1 (SP4-R)) is directed against the Cyclin D1 molecule, a key cell cycle regulator, expressed primarily during the G1 phase...
VENTANA anti-E-cadherin (36) Mouse Monoclonal Primary Antibody is directed against human transmembrane protein E-cadherin expressed as a part of the cell-cell adhesion complex in epithelial tissues. Reduction or loss of...
VENTANA anti-Helicobacter pylori (SP48) Rabbit Monoclonal Primary Antibody is designed to qualitatively detect the presence of Helicobacter pylori in formalin-fixed, paraffin-embedded gastric biopsy tissue via light microscopy. Immunohistochemical staining with...
VENTANA anti-p120 catenin (98) Mouse Monoclonal Primary Antibody is directed against human juxtamembrane protein p120 expressed as a part of the cell-cell adhesion complex in epithelial tissues. Cytoplasmic accumulation of...
VENTANA anti-p63 (4A4) Mouse Monoclonal Primary Antibody is directed against the p63 molecule which is highly expressed in the nuclei of human prostatic basal cells and urothelial tissues. This antibody...
VENTANA Basal Cell Cocktail (34ßE12+p63) is an antibody cocktail of anti-p63 (4A4) and anti-keratin (34ßE12). Anti-p63 (4A4) reacts with the p63 molecule in the nuclei of human prostatic basal cells...
Ventana Medical Systems’ PATHWAY anti-c-KIT (9.7) Primary Antibody is intended for laboratory use, via light microscopy, for the qualitative detection of KIT protein in formalin-fixed, paraffin-embedded gastrointestinal stromal tumors (GISTs)...
Ventana's OptiView DAB IHC Detection Kit (OptiView) is an indirect, biotin-free system for detecting mouse IgG, mouse IgM and rabbit primary antibodies. OptiView uses a proprietary, non-endogenous hapten system to...
Ventana’s OptiView Amplification Kit (OptiView Amplification) can only be used with Ventana’s OptiView IHC DAB Kit and provides a significant increase in sensitivity without sacrificing specificity. OptiView Amplification builds on...
Villin is a 95kD glycoprotein of microvilli associated with rootlet formation in gastrointestinalmuco sal epithelium. Anti-Villin labels the brush border area in the gastrointestinal mucosalepithelium. This antibody has been useful...
Vimentin antigen is expressed in endothelial cells, fibroblasts, smooth muscle cells and lymphoid cells. A number of tumors co-express vimentin and cytokeratin, for example, thyroid carcinomas, pleomorphic adenomas of the...
Vimentin is the major and usually only intermediate filament in a variety of non muscle mesenchymal cells, including all fibroblastic cells, endothelial cells, lipocytes, Schwann cells and macrophages. The pattern...
WT1 is a suppressor gene located on chromosome 11p13 . Wilms' Tumor Protein (WT1) has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian cystadenocarcinoma, gonadoblastoma, nephroblastoma and desmoplastic small...
ZAP-70 is a 70 kD protein tyrosine kinase found in T cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP-70 protein is expressed...