Ventana Medical Systems, Inc. CONFIRM Cytokeratin 760-2521

CONFIRM anti-Cytokeratin (AE1) may be used to aid in the identification of cells of normal and abnormal epithelial lineage as an aid in diagnosis of anaplastic tumors. CONFIRM anti-Cytokeratin (AE1) recognizes an epitope found on human callus cytokeratins; it reacts with the 56.5 kD, 50 kD, 50' kD, 48 kD, and 40 kD cytokeratins of the acidic subfamily. Because specific combinations of cytokeratin peptides are associated with different epithelial cells, these peptides are clinically important markers for classifying carcinomas (tumors of epithelial origin) and for distinguishing carcinomas from malignant tumors of non epithelial origin such as lymphomas melanomas, and sarcomas.