Fitzgerald Industries International, Inc. Datasheets for Biological Materials

Biological materials are biocompatible materials, natural or man-made, that comprise a whole or a part of a living structure or biomedical device that performs, augments, or replaces a natural function
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Product Name Notes
Mouse monclonal p0071 antibody Background: p0071 is specific for a subtype of adherens junctions, with a molecular mass of 135 kD and is closely related to neurojungin / delta-catenin and...
Mouse monoclonal 26S Proteasome P27 Subunit antibody Background: In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteasome pathway. The 26S proteasome is a 2.5-MDa...
Mouse monoclonal 26S Proteasome P32 Subunit antibody Background: In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteasome pathway. The 26S proteasome is a 2.5-MDa...
Mouse monoclonal 26S Proteasome P52 Subunit antibody Background: In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteasome pathway. The 26S proteasome is a 2.5-MDa...
Mouse monoclonal 3-hydroxycotinine antibody Background: 3-hydroxycotinine is an additional major metabolite of nicotine other than cotinine. Monoclonal antibody to 3-hydroxycontinine can be used to distinguish smokers from nonsmokers and to...
Mouse monoclonal AAV 1 (intact particle) antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause...
Mouse monoclonal AAV 4 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and...
Mouse monoclonal AAV 5 (intact particle) antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause...
Mouse monoclonal AAV 5 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and...
Mouse monoclonal AAV intact particle antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease...
Mouse monoclonal AAV Replicase antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and...
Mouse monoclonal AAV VP1 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and...
Mouse monoclonal AAV VP1/VP2 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and...
Mouse monoclonal AAV VP1/VP2/VP3 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and...
Mouse monoclonal AAV1 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently...
Mouse monoclonal AAV6 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently...
Mouse monoclonal AAV8/9 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently...
Mouse monoclonal AAV9 antibody Background: Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease and consequently...
Mouse monoclonal AIF antibody Background: A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl-2 family proteins,...
Mouse monoclonal AKT antibody Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and...
Mouse monoclonal AKT2 antibody Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and...
Mouse monoclonal Albumin antibody Background: Albumin refers generally to any protein that is water soluble, which is moderately soluble in concentrated salt solutions, and experiences heat denaturation. They are commonly...
Mouse monoclonal ALDH1A1 antibody Background: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two...
Mouse monoclonal alpha 2 Antiplasmin antibody Background: Alpha 2-antiplasmin is a serine protease inhibitor (serpin) responsible for inactivating plasmin, an important enzyme that participates in fibrinolysis and degradation of various...
Mouse monoclonal ALPP antibody Background: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome...
Mouse monoclonal AMACR antibody Background: Several studies have suggested that AMACR can be used as a prostate cancer biomarker. AMACR deficiency has recently been discovered. The first documented case was...
Mouse monoclonal AMACR antibody Background: The AMACR gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is...
Mouse monoclonal Amphetamine antibody Background: Amphetamine is a psychostimulant drug of the phenethylamine class that is known to produce increased wakefulness and focus in association with decreased fatigue and appetite.
Mouse monoclonal AMPK alpha 1 antibody Background: 5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this...
Mouse monoclonal Androgen Receptor antibody Background: Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding. This...
Mouse monoclonal APAAP Complex antibody Background: The use of a monoclonal alkaline phosphatase anti-alkaline phosphatase (APAAP) complex, in conjunction with a suitable primary antibody and a secondary bridging antibody results...
Mouse monoclonal Apolipoprotein E antibody Background: Apolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions...
Mouse monoclonal ApoO antibody Background: This protein is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded...
Mouse monoclonal ATF2 antibody Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive...
Mouse monoclonal ATM antibody Background: Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate...
Mouse monoclonal ATP2C1 antibody Background: The ATP2C1 protein belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of...
Mouse monoclonal ATXN1 antibody Background: Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative...
Mouse monoclonal AURKA antibody Background: Aurora A kinase also known as serine/threonine-pro tein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. Aurora A is...
Mouse monoclonal Bcl 2 antibody Background: Bcl-2 (B-cell lymphoma 2) is the founding member of the Bcl-2 family of apoptosis regulator proteins encoded by the BCL2 gene. Bcl-2 derives its...
Mouse monoclonal Bcl 2 antibody Background: Bcl-2 exerts a survival function in response to a wide range of apoptotic stimuli through inhibition of mitochondrial cytochrome c release. It has been...
Mouse monoclonal BCL10 antibody Background: Bcl10/CIPER/CLAP/mE1 0 is a widely expressed CARD (caspase recruitment domain) containing protein shown to induce apoptosis and activate NF-KB. The CARD domain mediates self-oligomerization ,...
Mouse monoclonal BDH1 antibody Background: BDH1 is a member of the short-chain dehydrogenase/reduct ase gene family. It forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific...
Mouse monoclonal beta Actin antibody Background: Actin, a ubiquitous eukaryotic protein, is the major component of the cytoskeleton. At least six isoforms are known in mammals. Nonmuscle beta- and gamma-actin,...
Mouse monoclonal beta Actin antibody Background: Beta-actin (gene name ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle...
Mouse monoclonal beta Actin antibody Background: Beta-actin is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins...
Mouse monoclonal beta Catenin antibody Background: Beta-catenin (or beta-catenin) is a protein that in humans is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. beta-catenin...
Mouse monoclonal beta Catenin antibody Background: Beta-catenin is a protein that in humans is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. Beta-catenin is a...
Mouse monoclonal beta Tubulin 3 antibody Background: The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building...
Mouse monoclonal beta Tubulin antibody Background: Tubulin is a major cytoskeleton component that has five distinct forms. Multiple beta Tubulin isoforms have been characterized and are expressed in mammalian tissues.
Mouse monoclonal beta Tubulin antibody Background: Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are alpha-tubulin and...
Mouse monoclonal BID antibody Background: BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading...
Mouse monoclonal BLK antibody Background: BLK is a modulator of beta-cells function, acting through the up-regulation of PDX1 and NKX6-1 and consequent stimulation of insulin secretion in response to glucose.
Mouse monoclonal BMPR2 antibody Background: Bone morphogenetic protein receptor type II or BMPR2 is a serine/threonine receptor kinase. It binds Bone morphogenetic proteins, members of the TGF beta superfamily of...
Mouse monoclonal BRAF antibody Background: Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome); also known as cardio-facio-cutaneo us syndrome. CFC syndrome is characterized by a distinctive facial...
Mouse monoclonal Brg1 antibody Background: Transcription activator BRG1 also known as ATP-dependent helicase SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene. The protein encoded by...
Mouse monoclonal BTK antibody Background: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology...
Mouse monoclonal Butyrophilin antibody Background: Butyrophilin (Btn) genes constitute a subgroup of at least 10 genes in the Ig superfamily identified in human, mouse, cow, goat and other species. The...
Mouse monoclonal c myc antibody Background: Myc gene encodes for a transcription factor that is believed to regulate expression of 15% of all genes through binding on Enhancer Box sequences...
Mouse monoclonal c Myc Tag antibody Background: Myc (c-Myc) codes for a transcription factor that is located on chromosome 8 in humans and is believed to regulate expression of 15%...
Mouse monoclonal C1 inhibitor antibody Background: C1 inhibitor is a protease inhibitor belonging to the serpin superfamily. Its main function is the inhibition of the complement system to prevent spontaneous...
Mouse monoclonal C3 antibody Background: Native human C3 is a naturally glycosylated polypeptide containing two disulfide-linked chains. C3 is central to the activation of all three pathways of complement activation.
Mouse monoclonal C4 antibody Background: Complement component 4 is a protein involved in the complement system. It is cleaved into proteins 4a and 4b. C4a is an anaphylatoxin, C4b forms...
Mouse monoclonal CA9 antibody Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological...
Mouse monoclonal Cadherin 11 antibody Background: Cadherin 11 integral membrane proteins mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain,...
Mouse monoclonal Cadherin 6 antibody Background: Cadherin 6 protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic...
Mouse monoclonal Calnexin antibody Background: Calnexin (CNX) is a 90kDa integral protein of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single...
Mouse monoclonal Calreticulin antibody Background: Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding and apoptosis. Calcium is stored...
Mouse monoclonal Cardiac Actin antibody Background: Actin is a globular, roughly 42- kDa protein found in eukaryotic cells. It is also one of the most highly-conserved proteins, differing by no...
Mouse monoclonal CARM1 antibody Background: Protein arginine N-methyltransferases , such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methion ine to the side chain nitrogens of arginine residues...
Mouse monoclonal CBP Tag antibody Background: CBP tag antibody is part of the Tag series of antibodies, the best quality in the research. The immunogen of CBP tag antibody is...
Mouse monoclonal CBX1 antibody Background: CBX1 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and...
Mouse monoclonal CCK4 antibody Background: CCK4 is an Inactive tyrosine kinase involved in Wnt signaling pathway. It is a component of both the non-canonical (also known as the Wnt/planar cell...
Mouse monoclonal CCN#D3 antibody Background: S-specific cyclin-D3 is a protein that in humans is encoded by the CCND3 gene. The protein encoded by this gene belongs to the highly conserved...
Mouse monoclonal CD176 antibody Background: The Thomsen-Friedenreich antigen acts as an oncofetal antigen, with low expression in normal adult tissues but increasing to fetal levels of expression in hyperplasia or...
Mouse monoclonal CD21 antibody Background: Complement component (3d/Epstein Barr virus) receptor 2, also known as CR2 and CD21, is a protein involved in the complement system. It binds to iC3b...
Mouse monoclonal CD23 antibody Background: CD23, also known as Fc epsilon RII, or Fc-epsilon-RII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites,...
Mouse monoclonal CD276 antibody Background: CD276 is a transmembrane protein that regulates T-cell-mediated immune response. CD276 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis...
Mouse monoclonal CD3 antibody Background: The CD3 T-Cell Co-Receptor (CD stands for cluster of differentiation) is a protein complex and is composed of four distinct chains. In mammals, the complex...
Mouse monoclonal CD31 antibody Background: Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in human is encoded by the PECAM1...
Mouse monoclonal CD34 antibody Background: CD34 is a possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix...
Mouse monoclonal CD34 antibody Background: CD34 molecule is a cluster of differentiation molecule present on certain cells within the human body. It is a cell surface glycoprotein and functions as...
Mouse monoclonal CD35 antibody Background: CD35 is a human gene. This protein encoded by this gene is a member of the regulators of complement activation (RCA) family and is located...
Mouse monoclonal CD3E antibody Background: CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11. The...
Mouse monoclonal CD3G antibody Background: T-cell surface glycoprotein CD3 gamma chain is a protein that in humans is encoded by the CD3G gene. T cell antigen receptor (TCR) is associated...
Mouse monoclonal CD45 antibody Background: Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene. PTPRC is also...
Mouse monoclonal CD68 antibody Background: CD68 (Cluster of Differentiation 68) is a glycoprotein which binds to low density lipoprotein. It is expressed on monocytes/macrophage s. Immunohistochemistry can be used to...
Mouse monoclonal CD69 antibody Background: CD69 (Cluster of Differentiation 69) is a human transmembrane C-Type lectin protein encoded by the CD69 gene. The activation of T lymphocytes, both in vivo...
Mouse monoclonal CD89 antibody Background: CD89 is a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such...
Mouse monoclonal CDC25C antibody Background: Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant. As with other cell cycle proteins such...
Mouse monoclonal Cdk Activating Kinase antibody Background: CDK-activating kinase (CAK) activates the cyclin-CDK complex by phosphorylating threonine residue 160 in the CDK activation loop.
Mouse monoclonal CDK1 antibody Background: Cyclin dependent kinase 1 also known as Cdk1 or cell division control protein 2 homolog is a highly conserved protein that functions as a serine/threonine...
Mouse monoclonal CDK1 antibody Background: The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of...
Mouse monoclonal CDK4 antibody Background: Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating...
Mouse monoclonal CDK5 antibody Background: Cell division protein kinase 5 is an enzyme that in humans is encoded by the CDK5 gene. The protein encoded by this gene is part...
Mouse monoclonal CDK6 antibody Background: Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating...
Mouse monoclonal Cdk7 antibody Background: Cell division protein kinase 7 is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a...
Mouse monoclonal CDK9 antibody Background: CDK9 or cyclin-dependent kinase 9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a member of the cyclin-dependent protein...
Mouse monoclonal CEACAM5 antibody Background: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a human gene. Members of the CEACAM subfamily, including...
Mouse monoclonal CHD3 antibody Background: Chromodomain-helicas e-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene. This gene encodes a member of the CHD family...
Mouse monoclonal Chlamydia antibody Background: Chlamydia is a genus of bacteria that are obligate intracellular parasites. Chlamydia infections are the most common bacterial sexually transmitted infections in humans and are...
Mouse monoclonal CK7 antibody Background: KRT7 is a member of the keratin protein family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of...
Mouse monoclonal CKMB antibody (MM subunit) Background: Creatine kinase (CK) is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate...
Mouse monoclonal Clathrin antibody Background: Clathrin is a protein that plays a major role in the formation of coated vesicles. It forms a triskelion shape composed of three clathrin heavy...
Mouse monoclonal Complement C1q antibody Background: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q...
Mouse monoclonal cotinine antibody Background: Cotinine is a major metabolite of nicotine that exists in smoker?s body. Monoclonal antibody to cotinine can be used to distinguish smokers from nonsmokers and...
Mouse monoclonal COX4I1 antibody Background: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial is an enzyme that in humans is encoded by the COX4I1 gene. Cytochrome c oxidase (COX) is...
Mouse monoclonal CREB1 antibody Background: CAMP responsive element binding protein 1, also known as CREB-1, is a protein that in humans is encoded by the CREB1 gene. This protein binds...
Mouse monoclonal CSK antibody Background: CSK specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site.
Mouse monoclonal CTLA4 antibody (HRP) Background: CTLA4 is a protein that plays an important regulatory role in the immune system. In humans, the CTLA4 protein is encoded by the CTLA4...
Mouse monoclonal CTLA4 antibody Background: CTLA4 is a protein that plays an important regulatory role in the immune system. In humans, the CTLA4 protein is encoded by the CTLA4 gene.
Mouse monoclonal Cyclin B1 antibody Background: CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The protein encoded by this gene...
Mouse monoclonal Cyclin D1 antibody Background: Cyclin D1 is a protein that in humans is encoded by the CCND1 gene. The protein encoded by this gene belongs to the highly...
Mouse monoclonal Cyclin I antibody Background: Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes. Cyclins were...
Mouse monoclonal Cytokeratin (Pan) antibody Background: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The term "cytokeratin" began to be used in the...
Mouse monoclonal Cytokeratin 15 antibody Background: Cytokeratin 15 is expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of...
Mouse monoclonal Cytokeratin 16 antibody Background: KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and...
Mouse monoclonal Cytokeratin 18 antibody Background: KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found...
Mouse monoclonal Cytokeratin 19 antibody Background: KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are...
Mouse monoclonal DAXX antibody Background: DAXX Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with...
Mouse monoclonal DDR2 antibody Background: DDR2 belongs to the protein kinase family, one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups...
Mouse monoclonal DDX4 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration...
Mouse monoclonal delta Catenin antibody Background: Delta Catenin is a member of a subfamily of proteins with ten Armadillo-repeats. Like beta-catenin and gamma-catenin, delta-catenins seem to interact with presenilins. Catenin-presenilin...
Mouse monoclonal Desmin antibody Background: The cytoskeleton consists of three types of cytosolic fibers: microfilaments (actin filaments), intermediate filaments and microtubules. Major types of intermediate filaments are distinguished and expressed...
Mouse monoclonal Desmocollin 3 antibody Background: Desmocollin-3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the...
Mouse monoclonal Desmoglein 2 antibody Background: Desmoglein 2 is a protein that in humans is encoded by the DSG2 gene. Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other...
Mouse monoclonal Desmoglein 2 antibody Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate...
Mouse monoclonal Desmoplakin 1/2 antibody Background: Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques.
Mouse monoclonal Desmoplakin 1/2, DP I/II antibody Background: Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to...
Mouse monoclonal DKK3 antibody Background: DKK3, like DKK1, DKK2, and DKK4, possesses an N terminal signal peptide and 2 conserved cysteine rich domains, which are separated by a linker region...
Mouse monoclonal DNA PKcs antibody Background: DNA-dependent protein kinase, catalytic subunit, also known as DNA-PKcs, is an enzyme that in humans is encoded by the PRKDC gene. DNA-PKcs belongs to...
Mouse monoclonal DPYS antibody Background: Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major...
Mouse monoclonal DSG1 antibody Background: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial...
Mouse monoclonal DYKDDDDK Tag antibody Background: Epitope tags are useful for the labeling and detection of proteins using immunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are...
Mouse monoclonal Dynamin 1 antibody Background: DNM1 is a member of the dynamin subfamily of GTP-binding proteins. The protein possesses unique mechanochemical properties used to tubulate and sever membranes, and...
Mouse monoclonal Dynamin 2 antibody Background: Dynamin 2 is a microtubule-associat ed force-producing protein involved in building microtubule bundles, and it is able to bind and hydrolyze GTP. It is...
Mouse monoclonal E Cadherin antibody Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the...
Mouse monoclonal EGF antibody Background: Epithelial growth factor (EGF) is the prototypic member of a family of growth factors that are characterized by the presence of EGF like domains and...
Mouse monoclonal EGFR antibody Background: Epidermal growth factor receptor (EGFR) is a 170 kDa membrane protein first identified as a binding partner of EGF. Also, EGFR phosphorylated itself (autophosphorylation )...
Mouse monoclonal EIF4E antibody Background: All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methyl-guanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved...
Mouse monoclonal Endostatin antibody Background: Endostatin is a naturally occurring 20 kDa polypeptide derived from the C-terminal portion of type XVIII collagen. It functions as an anti-angiogenic cytokine that is...
Mouse monoclonal EpCAM antibody (FITC) Background: EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with...
Mouse monoclonal EPCAM antibody Background: EGP40 is a 40 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on...
Mouse monoclonal EpCAM antibody Background: EpCAM is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas. Its constitutional function is being elucidated. It is intricately linked with the...
Mouse monoclonal EphA1 antibody Background: EPH receptor A1 (ephrin type-A receptor 1) is a protein that in humans is encoded by the EPHA1 gene. This gene belongs to the ephrin...
Mouse monoclonal EphA7 antibody Background: Ephrin type-A receptor 7 is a protein that in humans is encoded by the EPHA7 gene. This gene belongs to the ephrin receptor subfamily of...
Mouse monoclonal EphB1 antibody Background: Ephrin type-B receptor 1 is a protein that in humans is encoded by the EPHB1 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous...
Mouse monoclonal EphB2 antibody Background: Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous...
Mouse monoclonal EPO antibody Background: This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found...
Mouse monoclonal ERK1 antibody Background: Extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to...
Mouse monoclonal ERK1/2 antibody Background: Extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to...
Mouse monoclonal ERN1 antibody Background: Serine/threonine-pro tein kinase/endoribonucle ase IRE1 is an enzyme that in humans is encoded by the ERN1 gene. The protein encoded by this gene is the...
Mouse monoclonal Estrogen Receptor alpha antibody Background: The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons, being translated into a protein with six...
Mouse monoclonal FABP2 antibody Background: FABP2, also known as intestinal fatty acid binding protein 2 (I-FABP), is expressed in the epithelium of the small intestine by mature enterocytes. FABP2 is...
Mouse monoclonal FABP7 antibody Background: FABP7 (Fatty acid binding protein 7) is also known as brain fatty acid-binding protein (B-FABP) and is a member of fatty acid-binding proteins (FABPs) which...
Mouse monoclonal Factor B antibody Background: Factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. It is an essential component of the alternative pathway of...
Mouse monoclonal Factor I antibody Background: Factor I (Fibrinogen) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. This is...
Mouse monoclonal Factor VIIIc antibody Background: Factor VIII is a large glycoprotein (320 kDa) that circulates in plasma at approximately 200 ng/ml. Synthesized in the liver, the majority of Factor...
Mouse monoclonal Factor VIIIc antibody Background: Factor VIII is a large glycoprotein (320 kDa) that circulates in plasma at approximately 200 ng/ml. The Factor VIII gene produces two alternatively spliced...
Mouse monoclonal FAK antibody Background: PTK2 protein tyrosine kinase 2 (PTK2), also known as Focal Adhesion Kinase (FAK), is a protein that, in humans, is encoded by the PTK2 gene.
Mouse monoclonal FER antibody Background: Proto-oncogene tyrosine-protein kinase FER is an enzyme that in humans is encoded by the FER gene. Fer protein is a member of the FPS/FES family...
Mouse monoclonal FGF basic antibody Background: FGF basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and...
Mouse monoclonal FGR antibody Background: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a...
Mouse monoclonal FLAG antibody Background: FLAG tag is a polypeptide protein tag that can be added to a protein using recombinant DNA technology. It can be used for affinity chromatography,...
Mouse monoclonal Flag Tag antibody Background: FLAG-tag, or FLAG octapeptide, is a polypeptide protein tag that can be added to a protein using recombinant DNA technology. It can be used...
Mouse monoclonal FMR1 antibody Background: FMR1 is a translation repressor. A Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex...
Mouse monoclonal FOXD3 antibody Background: FOXD3 binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT -3' and acts as a transcriptional repressor. It also acts as a transcriptional activator and promotes development of...
Mouse monoclonal Galectin 3 antibody Background: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The...
Mouse monoclonal GAPDH antibody Background: Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon...
Mouse monoclonal GAPDH antibody Background: Glyceraldehyde-3-pho sphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-pho sphate during glycolysis. Though differentially expressed from tissue to tissue, GAPDH is thought to be a...
Mouse monoclonal GATA1 antibody Background: GATA1 is in the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin...
Mouse monoclonal GCLM antibody Background: Glutamate-cysteine ligase, also known as gamma-glutamylcystei ne synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy...
Mouse monoclonal GCSF antibody (HRP) Background: GCSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature...
Mouse monoclonal GCSF antibody Background: GCSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell.
Mouse monoclonal GFAP antibody Background: Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) protein that was thought to be specific for astrocytes in the central nervous system (CNS).
Mouse monoclonal GFAP antibody Background: The glial fibrillary acidic protein (GFAP) gene encodes one of the major intermediate filament proteins of mature astrocytes with multiple isoforms present in the CNS.
Mouse monoclonal GFP Tag antibody Background: The green fluorescent protein (GFP) is a protein composed of 238 amino acid residues (26.9kDa) that exhibits bright green fluorescence when exposed to blue...
Mouse monoclonal GFP Tag antibody Background: The green fluorescent protein (GFP) was originally identified as a protein involved in the bioluminescence of the jellyfish Aequorea victoria. GFP cDNA produces a...
Mouse monoclonal GOT2 antibody Background: Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in...
Mouse monoclonal GPD1 antibody Background: GPD1L belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. Defects in GPD1L are the cause of Brugada syndrome type 2 (BRS2) and sudden infant death syndrome...
Mouse monoclonal GPI antibody Background: This protein belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is...
Mouse monoclonal GRK2 antibody Background: GRK2 specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes...
Mouse monoclonal GSK3 alpha antibody Background: Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine...
Mouse monoclonal GSK3 beta antibody Background: Glycogen synthase kinase-3 (GSK-3) was initially identified as an enzyme that regulates glycogen synthesis in response to insulin. GSK-3 is a ubiquitously expressed serine/threonine...
Mouse monoclonal GST antibody Background: Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial, and microsomal (now designated as MAPEG) proteins. GSTs are present in eukaryotes...
Mouse monoclonal GST Tag antibody Background: Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial, and microsomal (now designated as MAPEG) proteins. GSTs are present in...
Mouse monoclonal GST Tag antibody Background: Plasmid vectors for the expression of coding regions of eukaryotic genes in E. coli are in common usage; such expression vectors often encode hybrid...
Mouse monoclonal HA antibody Background: Hemagglutinin refers to a substance that causes red blood cells to agglutinate. This process is called hemagglutination. Examples include antibodies, blood group antigens, autoimmune factors...
Mouse monoclonal HA antibody Background: The HA (human influenza hemagglutinin) epitope tag is frequently engineered onto the N- or C- terminus of a protein of interest so that the tagged...
Mouse monoclonal HA Tag antibody Background: Human influenza hemagglutinin (HA) is a surface glycoprotein required for the infectivity of the human virus. The HA tag is derived from the HA...
Mouse monoclonal HA Tag antibody Background: Plasmid vectors for the expression of coding regions of eukaryotic genes in bacterial, insect and mammalian hosts are in common usage; such expression vectors...
Mouse monoclonal Hantaan Virus antibody Background: Hantaviruses are negative sense RNA viruses in the Bunyaviridae family. Humans may be infected with hantaviruses through rodent bites, urine, saliva or contact with...
Mouse monoclonal Hantavirus (Puumala) antibody Background: Hantaviruses are negative sense RNA viruses in the Bunyaviridae family. Humans may be infected with hantaviruses through rodent bites, urine, saliva or contact with...
Mouse monoclonal Hantavirus (Seoul) antibody Background: Hantaviruses are negative sense RNA viruses in the Bunyaviridae family. Humans may be infected with hantaviruses through rodent bites, urine, saliva or contact with...
Mouse monoclonal HBxAg antibody Background: The hepatitis B virus (HBV) protein HBx has been reported to induce liver cancer in transgenic mice and transactivates a variety of viral and cellular...
Mouse monoclonal HDAC3 antibody Background: Acetylation of the histone tail causes chromatin to adopt an "open" conformation, allowing increased accessibility of transcription factors to DNA. The identification of histone acetyltransferases...
Mouse monoclonal HDAC3 antibody Background: HDAC3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives...
Mouse monoclonal HDL antibody Background: HDL is the vehicle for reversed cholesterol transport and estrification, serving as a scavenger for free cholesterol during intravascular catabolism of lipoproteins. HDL levels are...
Mouse monoclonal HER2 antibody Background: HER2/neu (also known as ErbB-2) stands for "Human Epidermal growth factor Receptor 2" and is a protein giving higher aggressiveness in breast cancers. It is...
Mouse monoclonal HER3 antibody Background: Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene. This gene encodes a member of the epidermal growth...
Mouse monoclonal Hexokinase 1 antibody Background: Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and...
Mouse monoclonal Hexokinase 2 antibody Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle.
Mouse monoclonal HIF1 alpha antibody Background: Hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor), also known as HIF1A, is a protein that in humans is encoded by the HIF1A...
Mouse monoclonal Hip antibody Background: Huntingtin Interacting Protein or Hip-1 for short is a protein that interacts with the huntingtin protein. It is known to contain a domain homologous to...
Mouse monoclonal His Tag antibody Background: A polyhistidine-tag is an amino acid motif in proteins that consists of at least five histidine (His) residues, often at the N- or C-terminus...
Mouse monoclonal His Tag antibody Background: Plasmid vectors for the expression of coding regions of eukaryotic genes in bacterial, insect and mammalian hosts are in common usage; such expression vectors...
Mouse monoclonal HNRNPA0 antibody Background: HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear...
Mouse monoclonal HSP27 antibody Background: Heat shock protein 27 (Hsp27) also known as heat shock protein beta-1 (HSPB1) is a protein that in humans is encoded by the HSPB1 gene.
Mouse monoclonal HSP60 antibody Background: Heat shock proteins are generally responsible for preventing damage to proteins in response to high levels of heat. Heat shock proteins are classified into six...
Mouse monoclonal HSP70 antibody Background: HSP70 and HSP90 are molecular chaperones expressed constitutively under normal conditions to maintain protein homeostasis and are induced upon environmental stress. Both HSP70 and HSP90...
Mouse monoclonal HSP70 antibody Background: The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living...
Mouse monoclonal HSPA5 antibody Background: Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a HSP70 molecular chaperone...
Mouse monoclonal IFN alpha antibody Background: The IFN-alpha proteins are produced by leukocytes. They are mainly involved in innate immune response against viral infection. They come in 14 subtypes that...
Mouse monoclonal IGF2BP3 antibody Background: The protein encoded by the IGFBP3 gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth...
Mouse monoclonal IKBKB antibody Background: IKK-beta also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of...
Mouse monoclonal IKK alpha antibody Background: Inhibitor of nuclear factor kappa-B kinase subunit alpha (IKK-alpha) also known as IKK1 or conserved helix-loop-helix ubiquitous kinase (CHUK) is a protein kinase that...
Mouse monoclonal IL-1ra antibody Background: IL1RA is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and...
Mouse monoclonal IL11 antibody Background: IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues...
Mouse monoclonal IL17 antibody Background: The originally described IL17 protein, now known as IL17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on...
Mouse monoclonal IL2 antibody Background: Interleukin 2 (IL2) is an interleukin which is a leukocytotrophic hormone that is instrumental in the body's natural response to microbial infection and in discriminating...
Mouse monoclonal IL34 antibody Background: Interleukin-34, or IL-34 is a protein belonging to a group of cytokines called interleukins. It was originally identified in humans, by large scale screening of...
Mouse monoclonal ILF2 antibody Background: Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in...
Mouse monoclonal Integrin alpha5 antibody Background: Integrin alpha-V (CD51) is a protein that in humans is encoded by the ITGAV gene. ITAGV encodes integrin alpha chain V. Integrins are heterodimeric...
Mouse monoclonal ISG15 antibody Background: Interferon-induced 17 kDa protein is a protein that in humans is encoded by the ISG15 gene.[1][2] ISG15 shares several common properties with other ubiquitin-like molecules...
Mouse monoclonal ISL1 antibody Background: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the ISL1 gene. This gene encodes a transcription factor containing two...
Mouse monoclonal JAK3 antibody Background: Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors.
Mouse monoclonal JNK3 antibody Background: The stress-activated protein kinase/Jun-amino-ter minal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory...
Mouse monoclonal KARS antibody Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which...
Mouse monoclonal KDM3A antibody Background: KDM3A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. It preferentially demethylates mono- and...
Mouse monoclonal KDM3A antibody Background: KDM3A is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated...
Mouse monoclonal KDM4A antibody Background: KDM4A is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain,...
Mouse monoclonal KDR antibody Background: Kinase insert domain receptor (KDR, a type III receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor.
Mouse monoclonal Keratin 17 antibody Background: KRT17 is type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in its...
Mouse monoclonal Keratin K17 antibody Background: Keratin, type I cytoskeletal 17 is a protein that in humans is encoded by the KRT17 gene. Keratin 17 is a type I cytokeratin.
Mouse monoclonal Keratin K18 antibody Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the...
Mouse monoclonal Keratin K18 antibody Background: Keratin, type I cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the...
Mouse monoclonal Keratin K18 Multiepitope antibody Background: Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of...
Mouse monoclonal Keratin K19 antibody Background: Keratin 19 is a type I keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains.
Mouse monoclonal Keratin K2 antibody Background: Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human skin. It...
Mouse monoclonal Keratin K20 antibody Background: Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. Keratin 20 is a type I cytokeratin.
Mouse monoclonal Keratin K5/K8 (Pan Epithelial) antibody Background: Keratin K5 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are...
Mouse monoclonal Keratin K7 antibody Background: Keratin, type I cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded...
Mouse monoclonal Keratin K8 antibody Background: Keratin, type I cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the...
Mouse monoclonal Keratin pan antibody Background: Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human skin. It...
Mouse monoclonal Keratin Type II antibody Background: Type II keratins (or Type II cytokeratins) constitutes the Type II intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present in all...
Mouse monoclonal KI67 antibody Background: Antigen KI-67 also known as Ki-67 or MKI67 is a protein that in humans is encoded by the MKI67 gene (antigen identified by monoclonal antibody...
Mouse monoclonal KIF7 antibody Background: KIF7 acts as both a negative and positive regulator of sonic hedgehog (Shh) pathway, acting downstream of SMO. Negatively regulates the pathway by preventing inappropriate...
Mouse monoclonal KLF4 antibody Background: KLF4 is a transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. It binds to the promoter region of...
Mouse monoclonal KLHL11 antibody Background: Kelch proteins (and Kelch-like proteins) are a widespread group of proteins that contain multiple Kelch motifs. The kelch domain generally occurs as a set of...
Mouse monoclonal KLHL11 antibody Background: KLHL11 contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five Kelch repeats. The function of KLHL11 remains unknown.
Mouse monoclonal KLHL13 antibody Background: Kelch proteins (and Kelch-like proteins) are a widespread group of proteins that contain multiple Kelch motifs. The kelch domain generally occurs as a set of...
Mouse monoclonal La antibody Background: La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and...
Mouse monoclonal Lactoferrin antibody Background: Lactoferrin is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely...
Mouse monoclonal Lamin antibody Background: Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact...
Mouse monoclonal Lamin Type A and C antibody Background: Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell...
Mouse monoclonal Lamin Type B2 / LIII antibody Background: Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell...
Mouse monoclonal LCN1 antibody Background: Lipocalin-1 is a protein that in humans is encoded by the LCN1 gene. The protein encoded by this gene belongs to the lipocalin family. Lipocalins...
Mouse monoclonal LDL antibody Background: Low-density lipoprotein (LDL) is one of the five major groups of lipoproteins, which in order of size, largest to smallest, are chylomicrons, VLDL, IDL, LDL...
Mouse monoclonal LIN28 antibody Background: Lin-28 homolog A is a protein that in humans is encoded by the LIN28 gene. It is a marker of undifferentiated human embryonic stem cells...
Mouse monoclonal LKB1 antibody Background: Serine/threonine kinase 11 also known as LKB1 or renal carcinoma antigen NY-REN-19 or is a protein kinase that in humans is encoded by the STK11...
Mouse monoclonal LPP antibody Background: LPP (LIM containing lipoma preferred partner), is a scaffolding protein which contains three LIM domains at its carboxy terminus, preceded by a proline rich pre...
Mouse monoclonal LRP antibody Background: Lung Resistance Related Protein is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.
Mouse monoclonal LSD1 antibody Background: LSD1 is a histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending...
Mouse monoclonal Lysozyme antibody Background: Lysozyme, also known as muramidase or N-acetylmuramide glycanhydrolase, are glycoside hydrolases, enzymes that damage bacterial cell walls by catalyzing hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid...
Mouse monoclonal M13/fd/F1 antibody Background: A filamentous phage is a type of bacteriophage shaped like a rod filament. Filamentous phages usually contain a genome of single-stranded DNA and infect Gram-negative...
Mouse monoclonal Mammaglobin 1 antibody Background: Mammaglobin is a gene that encodes a 10-kilodalton glycoprotein. In humans expression of the gene is limited to the adult mammary gland, a correlation...
Mouse monoclonal MAPK10 antibody Background: Mitogen-activated protein kinase 10 is an enzyme that in humans is encoded by the MAPK10 gene. The protein encoded by this gene is a member...
Mouse monoclonal MAPK6 antibody Background: Mitogen-activated protein kinase 6 is an enzyme that in humans is encoded by the MAPK6 gene. The protein encoded by this gene is a member...
Mouse monoclonal MAT1A antibody Background: The MAT1A gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which...
Mouse monoclonal MBP antibody Background: The maltose binding protein (MBP) from E. coli is a commonly used fusion partner for recombinant protein expression. MBP has been reported to enhance the...
Mouse monoclonal MBP Tag antibody Background: Epitope tagging offers an easy and universal strategy for the identification and purification of proteins derived by recombinant DNA technology. The insertion of a...
Mouse monoclonal MDM4 antibody Background: Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene. The human MDM4 gene, which plays a role in apoptosis, encodes...
Mouse monoclonal MDMA antibody Background: MDMA (3,4-Methylenedioxym ethamphetamine) ? colloquially known as ecstasy, often abbreviated "E" or "X" ? is an entactogenic drug of the phenethylamine and amphetamine class of...
Mouse monoclonal MEK2 antibody Background: MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth...
Mouse monoclonal MELAN A antibody Background: The antibody recognizes an 18 kDa protein (corresponding to MART-1, melanoma antigen recognized by T cells 1). MART-1 / MELAN A is a melanocyte...
Mouse monoclonal Metadherin antibody Background: Metadherin, also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene. AEG-1...
Mouse monoclonal MKK4 antibody Background: The MKK4 gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP...
Mouse monoclonal MKK6 antibody Background: The MKK6 gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also...
Mouse monoclonal MLH1 antibody Background: MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), also known as MLH1, is a human gene located on Chromosome 3. It is a...
Mouse monoclonal MRP antibody Background: MRP is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. More specifically, this...
Mouse monoclonal Multi-Epitope Cocktail to Nucleolar Organizer Region antibody Background: The nucleolus organizer region (NOR) or nucleolar organizer is a chromosomal region around which the nucleolus forms. This region is...
Mouse monoclonal Myc Tag antibody Background: A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA...
Mouse monoclonal Myc Tag antibody Background: Epitope tags are useful for the labeling and detection of proteins using immunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are...
Mouse monoclonal MYH1 antibody Background: Myosin-1 is a protein that in humans is encoded by the MYH1 gene. Myosin is a major contractile protein which converts chemical energy into mechanical...
Mouse monoclonal MYST1 antibody Background: Probable histone acetyltransferase MYST1 is an enzyme that in humans is encoded by the MYST1 gene. The MYST family of histone acetyltransferases, which includes MYST1,...
Mouse monoclonal N Cadherin antibody Background: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to...
Mouse monoclonal NAC1 antibody Background: NAC1 functions as a transcriptional repressor and seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. It contributes...
Mouse monoclonal NF kB p65 antibody Background: NFkappaB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found...
Mouse monoclonal NGFR antibody Background: The p75 neurotrophin receptor (p75NTR), a member of the TNF receptor superfamily, is distinguished by multiple cysteine-rich ligand-binding domains, a single transmembrane sequence and a...
Mouse monoclonal NKX3 1 antibody Background: The homeodomain-containi ng transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of...
Mouse monoclonal NME1 antibody Background: Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their...
Mouse monoclonal Non-Filamentous Actin antibody Background: Actin is a globular, roughly 42-kDa protein found in eukaryotic cells. It is also one of the most highly-conserved proteins, differing by no more...
Mouse monoclonal NPM antibody Background: Nucleophosmin (NPM), also known as nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. NPM1 is associated...
Mouse monoclonal NRF2 antibody Background: NRF2 is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. It is important for the coordinated...
Mouse monoclonal NSE antibody Background: Neuron specific enolase (NSE), is an enzyme that in humans is encoded by the ENO2 gene. NSE is a phosphopyruvate hydratase. NSE is produced by...
Mouse monoclonal NUCB1 antibody Background: NUCB1 is a calcium (Ca2+) binding protein found in both Golgi and cytoplasm. It is thought to have a key role in Golgi calcium homeostasis...
Mouse monoclonal Nucleolar Helicase antibody Background: Helicases are a class of enzymes vital to all living organisms. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone,...
Mouse monoclonal Nucleolar Protein xNopp180 antibody Background: xNopp180 is a constitutively expressed nucleolar component and a specific marker for the dense fibrillar component of the interphase nucleolus.
Mouse monoclonal Nucleophosmin antibody Background: Nucleophosmin (NPM; also known as B23, NO38, or numatrin) is a nucleolar phosphoprotein that binds the tumor suppressors p53 and p19Arf and is thought to...
Mouse monoclonal Nucleoplasmic Protein AND-1 antibody Background: AND-1 is a 125 kD nucleoplasmic protein (acidic nucleoplasmic DNA-binding protein) in Xenopus. Immunolocalization studies showed a dispersed, finely granular distribution pattern throughout...
Mouse monoclonal NusA antibody Background: NusA modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination. E.coli derived transcription elongation factor NusA is a common used fusion...
Mouse monoclonal OATP2 antibody Background: The OATP2 encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of...
Mouse monoclonal OATP2/OATP8 antibody Background: The SLC22A gene family codes for organic anion transporter (OAT) proteins. The OAT family plays the central role in renal organic anion transport. OATP2 and...
Mouse monoclonal Oct 4 antibody Background: Oct-4 (octamer-binding transcription factor 4) also known as POU5F1 (POU domain, class 5, transcription factor 1) is a protein that in humans is encoded...
Mouse monoclonal Oct1 antibody Background: Oct1 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA)...
Mouse monoclonal Oct4 antibody Background: Oct4 is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). It forms a trimeric complex with SOX2 on DNA and controls the expression...
Mouse monoclonal Osteoprotegerin antibody Background: Osteoprotegerin is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. Osteoprotegerin...
Mouse monoclonal p0071 antibody Background: p0071 is specific for a subtype of adherens junctions, with a molecular mass of 135 kD and is closely related to neurojungin / delta-catenin and...
Mouse monoclonal p21 Protein antibody Background: p21 is a potent cyclin-dependent kinase inhibitor. The p21 protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions...
Mouse monoclonal p44/42 MAPK antibody Background: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility,...
Mouse monoclonal P4HB antibody Background: P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a...
Mouse monoclonal p53 antibody Background: The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to...
Mouse monoclonal p53 Protein antibody Background: p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis.
Mouse monoclonal p63alpha antibody Background: Tumor protein p63 is a member of the p53 family of transcription factors. p63 -/- mice have several developmental defects which include the lack of...
Mouse monoclonal p97 ATPase antibody Background: p97 ATPase / VCP (also described as valosin-containing protein) is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion...
Mouse monoclonal p97 ATPase antibody Background: p97 ATPase is implicated in homotypic membrane fusion events and is related to the N-ethyl maleimide-sensitive fusion protein NSF/Sec18p. The antibody reacts with the...
Mouse monoclonal PAI-1 antibody Background: Plasminogen activator inhibitor-1 (PAI-1) is a serine protease inhibitor that is an important regulator of fibrinolysis and extracellular matrix turnover. PAI-1 may be important in...
Mouse monoclonal PAK2 antibody Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of...
Mouse monoclonal PARP antibody Background: PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved...
Mouse monoclonal PCNA antibody Background: Expression of proliferating cell nuclear antigen (PCNA) or cyclin or polymerase delta auxiliary protein is elevated in the nucleus during late G1 phase immediately before...
Mouse monoclonal PDHK1 antibody Background: Pyruvate dehydrogenase kinase (also pyruvate dehydrogenase complex kinase, PDC kinase, or PDK is a kinase enzyme which acts to inactivate the enzyme pyruvate dehydrogenase by...
Mouse monoclonal PEG10 antibody Background: PEG10 prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis and may also have a role in cell growth...
Mouse monoclonal Perilipin antibody Background: Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, perilipin A and B arise by alternative RNA splicing from a single gene, generating...
Mouse monoclonal PGA5 antibody Background: PGA5 (Pepsinogen 5, group I (pepsinogen A)), encodes pepsinogen. Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach.
Mouse monoclonal Pirh2 antibody Background: Pirh2 mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, HDAC1 and CDKN1B. It preferentially acts on tetrameric p53/TP53. It also contributes to...
Mouse monoclonal Plakophilin 1 antibody Background: Plakophilin-1 is a protein that in humans is encoded by the PKP1 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin...
Mouse monoclonal Plakophilin 2 antibody Background: Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin...
Mouse monoclonal Plant Actin antibody Background: Exogenous application of hormones initiates a variety of biochemical events in plants that culminate in processes directed by the cytoskeleton, such as the initiation...
Mouse monoclonal Plasminogen antibody Background: Plasminogen is the inactive precursor of the trypsin-like serine protease plasmin. It is normally found circulating through the blood stream. When plasminogen becomes activated and...
Mouse monoclonal Pneumocystis carinii antibody Background: Pneumocystis pneumonia or pneumocystosis is a form of pneumonia, caused by the yeast-like fungus (which had previously been erroneously classified as a protozoan) Pneumocystis...
Mouse monoclonal PPIA antibody Background: PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate...
Mouse monoclonal PRMT1 antibody Background: PRMTs are a family of proteins that either monomethylate or dimethylate the guanidino nitrogen atoms of arginine side chains. PRMT1 methylates Histone H4 on R3...
Mouse monoclonal Profilin antibody Background: Profilin is an actin-binding protein involved in the dynamic turnover and restructuring of the actin cytoskeleton. It is found in all eukaryotic organisms in most...
Mouse monoclonal Properdin antibody Background: Properdin or factor P is a globulin protein found in the blood serum of more complex animals. In the complement system, an innate-immunity series of...
Mouse monoclonal Prostate Specific Antigen antibody Background: PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in...
Mouse monoclonal Protein C Inhibitor antibody Background: Protein C inhibitor is a serine protease inhibitor (serpin) which limits the expression of protein C (an anticoagulant). An N-terminal fragment of PCI...
Mouse monoclonal PSIP1 antibody Background: PSIP1 is a transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses.
Mouse monoclonal PTEN antibody Background: As human tumors progress to advanced stages, one genetic alteration that occurs at high frequency is a loss of heterozygosity (LOH) at chromosome 10q23. Mapping...
Mouse monoclonal PTEN antibody Background: PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated...
Mouse monoclonal PTH1R antibody Background: Parathyroid hormone/parathyroid hormone-related peptide receptor also known as parathyroid hormone 1 receptor (PTH1R) is a protein that in humans is encoded by the PTH1R gene.
Mouse monoclonal PYK2 antibody Background: PYK2 is involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. PKY2 may represent an important signaling intermediate...
Mouse monoclonal Rab10 antibody Background: Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 protein has been shown to interact with AP1S1.
Mouse monoclonal Rab25 antibody Background: Rab25 is involved in the regulation of cell survival. Rab25 promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1...
Mouse monoclonal Rabies antibody Background: Rabies is a viral disease that causes acute encephalitis (inflammation of the brain) in warm-blooded animals. It is zoonotic most commonly transmitted by a bite...
Mouse monoclonal RFP Tag antibody Background: Red Fluorescent Protein is a protein which exhibits bright red fluorescence when exposed to blue light. Fluorescent proteins are members of a structurally homologous...
Mouse monoclonal Rheumatoid Factor antibody Background: Rheumatoid factor (RF or RhF) is an autoantibody (antibody directed against an organism's own tissues) most relevant in rheumatoid arthritis.[1] It is an antibody...
Mouse monoclonal RICTOR antibody Background: RICTOR is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in...
Mouse monoclonal RNA Polymerase II antibody Background: RNA polymerase II is an enzyme found in eukaryotic cells. It catalyzes the transcription of DNA to synthesize precursors of mRNA and most...
Mouse monoclonal Ro60 antibody Background: Ro60 is an RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.
Mouse monoclonal Rotavirus antibody Background: Rotavirus is the most common cause of severe diarrhoea among infants and young children, and is one of several viruses that cause infections often called...
Mouse monoclonal RSV antibody Background: Human respiratory syncytial virus (RSV) is a virus that causes respiratory tract infections. It is the major cause of lower respiratory tract infection and hospital...
Mouse monoclonal Rubeola virus antibody Background: The rubeola virus is the causative agent in measles, a systemic illness characterized by rash, conjunctivitis, and mucosal Koplik spots. Rubeola virus is not...
Mouse monoclonal S100A10/P11 antibody Background: S100-A10, also known as p11, is a protein that is encoded by the S100A10 gene in humans and the S100a10 gene in other species. S100-A10...
Mouse monoclonal SETDB1 antibody Background: Histone-lysine N-methyltransferase SETDB1 is an enzyme that in humans is encoded by the SETDB1 gene. The SET domain is a highly conserved, approximately 150-amino acid...
Mouse monoclonal Single Chain Urokinase antibody Background: Urokinase, also called urokinase-type plasminogen activator (uPA), is a serine protease. It was originally isolated from human urine. The primary physiological substrate is...
Mouse monoclonal SIRT1 antibody Background: SIRT1 is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. It deacetylates 'Lys-382' of p53/TP53 and...
Mouse monoclonal Sm B'B/D1 antibody Background: The smith antigen was found to be a complex of ribonucleic acid (RNA) molecules and multiple proteins. A set of uridine-rich small nuclear RNA...
Mouse monoclonal Sm B/B' antibody Background: The smith antigen was found to be a complex of ribonucleic acid (RNA) molecules and multiple proteins. A set of uridine-rich small nuclear RNA...
Mouse monoclonal Sm B/D1 antibody Background: The smith antigen was found to be a complex of ribonucleic acid (RNA) molecules and multiple proteins. A set of uridine-rich small nuclear RNA...
Mouse monoclonal Sm D1 antibody Background: The smith antigen was found to be a complex of ribonucleic acid (RNA) molecules and multiple proteins. A set of uridine-rich small nuclear RNA...
Mouse monoclonal SMAD3 antibody Background: Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-beta signals from the cell surface into...
Mouse monoclonal SMAD4 antibody Background: Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmits TGF-beta signals from the cell surface into...
Mouse monoclonal SMAD5 antibody Background: Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SMAD5 gene. SMAD5, as its name...
Mouse monoclonal SMAD6 antibody Background: Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-beta signals from the cell surface into...
Mouse monoclonal SMC1 antibody Background: Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA...
Mouse monoclonal Smooth Muscle Actin antibody Background: Actin is a globular, roughly 42-kDa moonlighting protein found in all eukaryotic cells (the only known exception being nematode sperm) where it may...
Mouse monoclonal Smyd1 antibody Background: SET and MYND domain containing 1 (SMYD1) acts as a transcriptional repressor and is essential for cardiomyocyte differentiation and cardiac morphogenesis.
Mouse monoclonal Smyd5 antibody Background: SMYD5 contains 1 MYND-type zinc finger and 1 SET domain. The exact function of SMYD5 remains unknown.
Mouse monoclonal SOD1 antibody Background: Superoxide dismutase 1 (SOD1) binds copper and zinc ions and is one of three isozymes responsible for destroying free superoxide radicals in the body. The...
Mouse monoclonal SORL1 antibody Background: SORL1 (also known as SORLA, SORLA1, or LR11) is a neuronal apolipoprotein E receptor, the gene for which is predominantly expressed in the central nervous...
Mouse monoclonal SOX2 antibody Background: SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells.
Mouse monoclonal SOX2 antibody Background: Transcription factor SOX-2 (SOX-2) is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in...
Mouse monoclonal SRA antibody Background: Steroid receptor RNA activator 1 also known as steroid receptor RNA activator protein (SRAP) is a protein that in humans is encoded by the SRA1...
Mouse monoclonal STAT6 antibody Background: STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the...
Mouse monoclonal STAT6 antibody Background: Upon activation by Janus kinases, Stat6 translocates to the nucleus where it regulates cytokine-induced gene expression. Stat6 is activated via phosphorylation at Tyr641 and is...
Mouse monoclonal Streptococcus B antibody Background: Streptococcus is a genus of spherical Gram-positive bacteria belonging to the phylum Firmicutes and the lactic acid bacteria group. Group B streptococcus causes pneumonia...
Mouse monoclonal SUZ12 antibody Background: Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene. This zinc finger gene has been identified at the breakpoints...
Mouse monoclonal SV40 Large T Antigen antibody Background: Simian virus 40, (SV40) is a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA...
Mouse monoclonal SYMPK antibody Background: Symplekin is a protein that in humans is encoded by the SYMPK gene. This gene encodes a nuclear protein that functions in the regulation of...
Mouse monoclonal SYP antibody Background: Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present in neuroendocrine cells and in virtually all neurons in the...
Mouse monoclonal t-PA antibody Background: Tissue plasminogen activator is a protein involved in the breakdown of blood clots. It is a serine protease found on endothelial cells, the cells that...
Mouse monoclonal T7 Tag antibody Background: The T7 tag is an 11 amino acid peptide encoded in the leader sequence of T7 bacteriophage gene10. This gene encodes a T7 major...
Mouse monoclonal TAB2 antibody Background: The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and...
Mouse monoclonal TCF3 antibody Background: Transcription factor 3 (E2A immunoglobulin enhancer-binding factors E12/E47), also known as TCF3, is a protein that in humans is encoded by the TCF3 gene. TCF3...
Mouse monoclonal THAP11 antibody Background: THAP11 is a transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses...
Mouse monoclonal Thyroid Transcription Factor 1 antibody Background: Thyroid transcription factor-1 (TTF-1) is a protein that regulates transcription of genes specific for the thyroid, lung, and diencephalon. It is also...
Mouse monoclonal TNF alpha antibody Background: TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to...
Mouse monoclonal TNFRII antibody Background: TNF RII is a high affinity receptor for TNF-alpha and -beta, potent mediators of multiple aspects of inflammatory immune responses. RII is a prototypic member...
Mouse monoclonal TORC1 antibody Background: CREB-regulated transcription coactivator 1 (CRTC1), previously referred to as TORC1 (Transducer Of Regulated CREB activity 1, not to be confused with the unrelated target of...
Mouse monoclonal TORC2 antibody Background: TORC2 is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in...
Mouse monoclonal Torc3 antibody Background: TORC3 acts as a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. It also acts as...
Mouse monoclonal TP53 antibody Background: Tumor protein p53 responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism.
Mouse monoclonal U1 snRNP A/B?? antibody Background: U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other...
Mouse monoclonal UHRF2 antibody Background: The UHRF2 gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear...
Mouse monoclonal URK antibody Background: Urokinase, also called urokinase-type plasminogen activator (uPA), is a serine protease. It was originally isolated from human urine. The primary physiological substrate is plasminogen, activation...
Mouse monoclonal V5 Tag antibody Background: Epitope tags consisting of short sequences recognized by well-characterizated antibodies have been widely used in the study of protein expression in various systems. The...
Mouse monoclonal V5 Tag antibody Background: The V5 epitope tag is derived from a small epitope (Pk) present on the P and V proteins of the paramyxovirus of simian virus...
Mouse monoclonal VCAM1 antibody Background: VCAM1 is important in cell-cell recognition. It appears to function in leukocyte-endothelia l cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates...
Mouse monoclonal Vimentin antibody Background: Vimentin is a member of the intermediate filament family of proteins that is especially found in connective tissue. Intermediate filaments are an important structural feature...
Mouse monoclonal Vimentin antibody Background: Vimentin is one of the five major groups of intermediate filaments, a distinct class of cytosekeletal proteins, occurring in mesenchymal cells. Localized vimentin can be...
Mouse monoclonal VSV G Tag antibody Background: Vesicular stomatitis virus (VSV), an enveloped RNA virus from the Rhabdoviridae family, is released from the plasma membrane of host cells by a...
Mouse monoclonal WIF1 antibody Background: Wnt inhibitory factor 1, also known as Wif-1, is a secreted protein that binds to Wnt proteins involved in the embryonic development and cancer, and...
Mouse monoclonal WNT1 antibody Background: WNT1 is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1...
Mouse monoclonal WNT10B antibody Background: WNT10B is the ligand for members of the frizzled family of seven transmembrane receptors. WNT10B is a probable developmental protein. It may be a signaling...
Mouse monoclonal WNT5a antibody Background: The Wnt family includes several secreted glycoproteins that play important roles in animal development. There are 19 Wnt genes in the human genome that encode...
Mouse monoclonal ZAP70 antibody Background: ZAP-70 is an abbreviation for Zeta-chain-associate d protein kinase 70 (70 is the molecular weight in kDa). The protein is a member in the protein-tyrosine...
Mouse monoclonal ZBTB7B antibody Background: Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene. ZFP67 is an early growth response...
Mouse polyclonal Bovine GFAP antibody Background: The glial fibrillary acidic protein (GFAP) gene encodes one of the major intermediate filament proteins of mature astrocytes with multiple isoforms present in the...
Mouse polyclonal Bovine S100 protein antibody Background: S100 proteins (16 members) show a very divergent pattern of cell and tissuespecific expression, of subcellular localizations and relocations, of posttranslational modifications, and...
Mouse polyclonal Human 14.3.3 gamma antibody Background: The 14-3-3 proteins are a family of conserved regulatory molecules expressed in all eukaryotic cells. A striking feature of the 14-3-3 proteins is...
Mouse polyclonal Human 14.3.3 tau antibody Background: 14-3-3 protein theta (tau) is a protein that in humans is encoded by the YWHAQ gene. This gene product belongs to the 14-3-3...
Mouse polyclonal Human Apo E antibody antibody Background: ApolipoproteinE (ApoE) is a structural component of very low density lipoprotein (VLDL) synthesized by the liver and intestinally synthesized chylomicrons. It is...
Mouse polyclonal Human APP antibody Background: Amyloid precursor protein (APP) is precursor protein of Amyloid beta which is major constituent of senile plaque in Alzheimer?s disease. It is known that...
Mouse polyclonal Human beta Amyloid antibody (biotin) Background: Alzheimer?s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles(NFTs) in the brain. The major protein component...
Mouse polyclonal Human beta Amyloid antibody Background: Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component...
Mouse polyclonal Human beta Amyloid antibody Background: Alzheimer?s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles(NFTs) in the brain. The major protein component of...
Mouse polyclonal Human c-Kit antibody Background: The proto-oncogene ckit encodes a transmembrane tyrosine kinase receptor, and its ligand for the cKit receptor has been identified as the stem cell factor...
Mouse polyclonal Human CEA antibody Background: Carcinoembryonic antigen (CEA) was reported as a cancer-specific antigen existing in human colon cancer tissue and embryo intestinal tract in 1965. However it was...
Mouse polyclonal Human COX2 antibody Background: Cyclooxygenase (COX) is a membrane bound enzyme responsible for the oxidation of arachidonic acid to Prostaglandin G2 (PGG2) and the subsequent reduction of PGG2...
Mouse polyclonal Human CRMP2 antibody Background: CRMP2 (Collapsin response mediator protein2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling.
Mouse polyclonal Human Cyclin D1 antibody Background: Bcl1/Cyclin D1 belongs to the G1 cyclins and plays a key role in cell cycle regulation during the G1/S transition by cooperating with...
Mouse polyclonal Human ERK antibody Background: The cell signaling molecules in the Mitogen-Activated Protein (MAP) kinase family play the central role in the cell response. Extracellular Signal-Regulated Kinase (ERK), cjun...
Mouse polyclonal Human ETBR antibody Background: Two kinds of receptors for Endothelin have been found, namely Endothelin A (ETA) receptor and Endothelin B (ETB) receptors. ETA receptor is ET1 specific...
Mouse polyclonal Human FAS antibody Background: Animal fatty acid synthase (FAS) is a homodimer protein, which synthesizes long-chain fatty acids and is expressed in liver, brain, breast and lung. However,...
Mouse polyclonal Human Galectin 3 antibody Background: Galectin is widely distributed in nematodes, insects, and porifers, as well as vertebrates, and it has also been found to be present in...
Mouse polyclonal Human Galectin3 antibody Background: Galectin is widely distributed in nematodes, insects, and porifers, as well as vertebrates, and it has also been found to be present in true...
Mouse polyclonal Human GCSF antibody Background: GCSF (Granulocyte Colony Stimulating Factor) is a cytokine which accelerates differentiation and multiplication of neutrophilic precursor cell. It is reported that GCSF is produced...
Mouse polyclonal Human KDR antibody Background: KDR, alternative name Flk1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt1 (type...
Mouse polyclonal Human KGF antibody Background: Keratinocyte Growth Factor (KGF) is a growth factor which affects epithelial cells specifically and it hardly affects mesenchymal cells like fibroblasts. Its receptor is...
Mouse polyclonal Human Langerhans Cells antibody Background: Langerhans cells (LC) were reported to function as the antigen-presenting cells in the skin. They express immune response gene-associated antigens on their cell...
Mouse polyclonal Human MBD3 antibody Background: Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG binding domain...
Mouse polyclonal Human MDMX antibody Background: The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or...
Mouse polyclonal Human Napsin A antibody Background: A new protein isolated by two-dimensional immunoelectrophoresi s from tissue of lung adenocarcinoma was identified as Napsin A, a new aspartic Proteinase. The...
Mouse polyclonal Human NP95 antibody Background: Np95 was originally found as a tumor-specific nuclear antigen of 95 kDa in mice. Experiments using B10 strains showed that Np95 is enriched in...
Mouse polyclonal Human OGG1 antibody Background: Oxidative damage to DNA has been proposed to have a role in cancer and ageing. Oxygen-free radicals formed during normal aerobic cellular metabolism attack...
Mouse polyclonal Human ORP150 antibody Background: Heat shock proteins (HSPs)/stress proteins are molecular chaperones that are induced by various environmental and physiological stimuli. The 150 kDa oxygen-regulated protein (ORP150), a...
Mouse polyclonal Human Osteopontin antibody Background: Osteopontin (OPN) is a secreted glycoprotein that was originally isolated from bone. Its molecular weights have been reported in the range of 66 kDa...
Mouse polyclonal Human p16INK4a antibody Background: p16INK4a is a cyclin-dependent kinase (CDK) inhibitor, and binds CDK4 and CDK6 inhibiting their kinase activity. It is also called MTS1 and INK4a, and...
Mouse polyclonal Human p53 antibody Background: p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 gene.
Mouse polyclonal Human Parkin antibody Background: Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of...
Mouse polyclonal Human PDGFR beta antibody Background: PDGF, a ligand of PDGFR, has 4 isofoms, A, B, C and D chains, and forms hetero and/or homo dimers, PDGFAA, AB, BB,...
Mouse polyclonal Human Presenilin 1 antibody Background: The presenilin 1 (PS1) gene was identified as the gene that harbors mutations that cause this type of FAD (termed AD3). PS1 is...
Mouse polyclonal Human Rad51 antibody Background: The highly conserved Saccharomyces cerevisiae Rad51 protein plays a central role in both mitotic and meiotic homologous DNA recombination. Seven members of the Rad51...
Mouse polyclonal Human Reticulocalbin 1 antibody Background: Human Reticulocalbin 1 is a 44kDa protein and belongs to the EF (elongation factor) and calcium binding protein family, and it is known...
Mouse polyclonal Human sAPP alpha antibody Background: Amyloid precursor protein (APP) is precursor protein of Amyloid beta which is major constituent of senile plaque in Alzheimer?s disease. It is known...
Mouse polyclonal Human SOCS3 antibody Background: The Janus family of protein tyrosine kinases (JAKs) and STAT transcription factors regulate cellular processes involved in cell growth, differentiation, and transformation through their...
Mouse polyclonal Human Tau antibody Background: Tau protein is a microtubule-associat ed protein expressed in neuroaxon and has molecular weight of 50-70 kDa. Some Alzheimer's patients have sites where tau...
Mouse polyclonal Human Tau/Amino Junction antibody Background: Tau protein is a microtubule-associat ed protein expressed in neuroaxons and has a molecular weight of 50-70 kDa. Some Alzheimer's patients have sites...
Mouse polyclonal Human Tau/E2 Junction antibody Background: Tau protein is a microtubule-associat ed protein expressed in neuroaxons and has molecular weight of 50-70 kDa. Some Alzheimer's patients have sites where...
Mouse polyclonal Human Tau/Repeat domain antibody Background: Tau protein is a microtubule-associat ed protein expressed in neuroaxon and has molecular weight of 50-70 kDa. Some Alzheimer's patients have sites where...
Mouse polyclonal Human Tenascin C antibody Background: TenascinC (TNC) is a component of the extracellular matrix (ECM) that has been shown to be involved in tissue interactions during fetal development...
Mouse polyclonal Human TIE1 antibody Background: TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa...
Mouse polyclonal Human VEGF antibody Background: Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculostellate cells and secreted by...
Mouse polyclonal Human YB1 antibody Background: YB1 (Ybox binding protein1) contains a highly conserved cold shock domain and is a transcription factor that binds to a CCAAT box. It has...
Mouse polyclonal mTOR antibody Background: Rapamycin is a lipophilic macrolide compound and induces a G1 phase growth arrest in S. cerevisiae and mammalian cells. The mammalian target of rapamycin (mTOR)...
Mouse polyclonal Neurofilament 160K, 210K antibody Background: Neurofilament is an intermediate filament which is expressed in nerve cells. The protein consists of three subunits, 200 kDa, 160 kDa and 6.8...
Mouse polyclonal NSE antibody Background: Enolase is an enzyme in the glycolysis system and the protein consists of a dimer structure selected from three subunits alpha, beta and gamma. As...
Mouse polyclonal Osteopontin N-Half antibody Background: Osteopontin (OPN) is a secreted glycoprotein that was originally isolated from bone. Its molecular weights have been reported in the range of 66 kDa...
Mouse polyclonal Rat CINC1 antibody Background: Cytokine-induced neutrophil chemo attractant 1(CINC1) was originally purified from media conditioned by IL1 beta stimulated rat kidney epithelioid cells (NRK52E). Amino acid sequence that...
Mouse polyclonal Rat CINC1 antibody Background: Cytokine-induced neutrophil chemo attractant 1(CINC1) was originally purified from media conditioned by IL1 beta stimulated rat kidney epithelioid cells (NRK52E). The amino acid sequence...
Mouse polyclonal Rat MCP1 antibody Background: Human macrophage/monocyte chemotactic and activating factor (MCAF) also called human macrophage chemoattractant protein 1 (MCP1) is an 8.6 kDa protein containing 76 amino acid...
Mouse polyclonal Rat Occludin antibody Background: Occludin is an approximately 60kDa integral membrane protein localizing at tight junctions and composed of a short N-terminal cytosolic domain, four transmembrane domains and...
Mouse polyclonal Rat SE1 cells antibody Background: Among the vascular endothelial cells, hepatic sinusoidal endothelial (HSE) cells are morphologically unique because they have open fenestrations in their cytoplasm and lack...
Mouse polyclonal Rat Tight junction associated protein antibody Background: Tight junctions function to maintain cellular polarity and permeability barriers in epithelial and endothelial cells. Recently, several component molecules of tight...
Mouse polyclonal Tob antibody Background: A cDNA for a novel protein termed Tob (Transducer of ErbB2) that interacts with the cerbB2 gene product p185erbB2 was molecularly cloned. Nucleotide sequencing reveals...
Rabbit monoclonal LDL receptor antibody Background: The Low-Density Lipoprotein Receptor is a mosaic protein of ~840 amino acids (after removal of signal peptide) that mediates the endocytosis of cholesterol-rich LDL.
Rat monoclonal APC protein antibody Background: APC is classified as a tumor suppressor gene. Tumor suppressor genes prevent the uncontrolled growth of cells that may result in cancerous tumors. The...
Rat monoclonal BORIS antibody Background: BORIS is a novel male germ-line-specific protein associated with epigenetic reprogramming events.
Rat monoclonal CLASP1 antibody Background: CLASPs, such as CLASP1, are nonmotor microtubule-associat ed proteins that interact with CLIPs. CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore...
Rat monoclonal CLASP2 antibody Background: CLASP2 is a microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. It is involved in the nucleation of noncentrosomal microtubules originating from...
Rat monoclonal CTCF antibody Background: The protein CTCF plays heavily in the role of repressing the insulin-like growth factor 2 gene, by binding to the H-19 imprinting control region (ICR)...
Rat monoclonal Delangin A antibody Background: Delangin proteins facilitate enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal...
Rat monoclonal Delangin B antibody Background: Delangin proteins facilitate enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal...
Rat monoclonal EB1 antibody Background: EB1 was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein...
Rat monoclonal EB2 antibody Background: EBS shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. The function of this protein is unknown; however, its homology suggests...
Rat monoclonal EB3 antibody Background: EB3 protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.
Rat monoclonal Fibrinogen antibody Background: Fibrinogen (factor I) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. This is achieved...
Rat monoclonal FOP antibody Background: FOP is a novel chromatin target of protein arginine methyltransferases. Human Fop is encoded by C1orf77, a gene of previously unknown function. Fop is tightly...
Rat monoclonal GATA3 antibody Background: GATA3 belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T cell development...
Rat monoclonal GMCSF antibody Background: GMCSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and...
Rat monoclonal GST antibody Background: Enzymes of the glutathione S-transferase (GST) family are composed of many cytosolic, mitochondrial, and microsomal proteins. GSTs are present in eukaryotes and in prokaryotes, where...
Rat monoclonal Human Growth Hormone antibody Background: Growth hormone (GH) is a protein-based peptide hormone. It stimulates growth, cell reproduction and regeneration in humans and other animals. Growth hormone is...
Rat monoclonal LGI4 antibody Background: LGI4 is a secreted and glycosylated leucine-rich repeat protein. LGI4 appears to be expressed in many tissues with highest expression in brain. Senechal et al...
Rat monoclonal LYL1 antibody Background: LYL1 may play a role in blood vessel maturation and hematopoeisis. A translocation between this locus and the T cell receptor beta locus on chromosome...
Rat monoclonal MTGR1 antibody Background: MTGR1 is a transcriptional corepressor that is required for maintenance of the secretory cell lineage in the small intestine.
Rat monoclonal Rab11B antibody Background: The Ras superfamily of small GTP-binding proteins, which includes the Ras, Ral, Rho, Rap, and Rab families, is involved in controlling a diverse set of...
Rat monoclonal Rab6B antibody Background: Rab6B seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Rat monoclonal SMC1A antibody Background: Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister...
Rat monoclonal SMC2 antibody Background: SMC2 is a subunit of condensin I and II, large protein complexes involved in chromosome condensation.
Rat monoclonal SMC3 antibody Background: The SMC3 protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form is a component of...
Rat monoclonal STAG2 antibody Background: STAG2 is a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which...

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