Mouse polyclonal Human CEA antibody
Background:
Carcinoembryonic antigen (CEA) was reported as a cancer-specific antigen existing in human colon cancer tissue and embryo intestinal tract in 1965. However it was denied that this was carcinoembryonic antigen later. CEA exists in the blood of patients with some benign diseases as well as with cancer. The production of CEA is observed in many cancer tissues and the CEA value in the blood reflects tumor size. Therefore, the assay is widely used in a diagnosis and in monitoring of cancer. CEA is a glycoprotein which has a molecular weight of about 180 kDa, and is detected as a broad band in the globlin area in electrophoresis. The bands are due to diversity of the carbohydrate portion and the carbohydrate content in CEA is 50?60%. CEA includes CEA related antigens which do not crossreact with CEA antisera such as NCA (nonspecific cross reacting antigen) derived from lung and spleen, NCA2 derived from the embryo stool, NFA1 (normal fecal antigen-1) derived from the normal adult stool and NFA2.
| Fitzgerald Industries International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | 10R-3020 |
| Product Name | CEA antibody |
