Fitzgerald Industries International, Inc. Datasheets for Biological Materials
Biological materials are biocompatible materials, natural or man-made, that comprise a whole or a part of a living structure or biomedical device that performs, augments, or replaces a natural function
Biological Materials: Learn more
| Product Name | Notes |
|---|---|
| Mouse monoclonal AATF antibody Background: The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the... | |
| Mouse monoclonal ABCF1 antibody Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and... | |
| Mouse monoclonal ABCF2 antibody Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and... | |
| Mouse monoclonal ACIN1 antibody Background: ACIN1 is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting... | |
| Mouse monoclonal ACTB antibody Background: Beta actin is one of six different actin isoforms which have been identified. ACTB is one of the two nonmuscle cytoskeletal actins. Actins are highly... | |
| Mouse monoclonal ADAM10 antibody Background: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. Sheddase, a generic name for... | |
| Mouse monoclonal ADNP antibody Background: Vasoactive intestinal peptide (VIP) is a neuroprotective factor that has been shown to have a stimulatory effect on the growth of some tumor cells and... | |
| Mouse monoclonal AGXT antibody Background: The AGXT gene provides instructions for making a liver enzyme called alanine-glyoxylate aminotransferase. Inside liver cells, this enzyme is found in peroxisomes, structures that contain... | |
| Mouse monoclonal AHCTF1 antibody Background: AHCTF1 is required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of... | |
| Mouse monoclonal AHNAK antibody Background: The AHNAK gene may be required for neuronal cell differentiation. | |
| Mouse monoclonal AKAP8 antibody Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein... | |
| Mouse monoclonal ANKRD11 antibody Background: May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. | |
| Mouse monoclonal AOF2 antibody Background: This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several... | |
| Mouse monoclonal APEX1 antibody Background: Apurinic/apyrimidini c (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. | |
| Mouse monoclonal APRIN antibody Background: This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome... | |
| Mouse monoclonal ARID1A antibody Background: This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes... | |
| Mouse monoclonal ARID2 antibody Background: ARID2 is involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF... | |
| Mouse monoclonal ARID3A antibody Background: This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead... | |
| Mouse monoclonal ARID4A antibody Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates... | |
| Mouse monoclonal ARNTL antibody Background: Aryl hydrocarbon receptor nuclear translocator-like, also known as ARNTL, Bmal1, or Mop3, is a gene which is associated with susceptibility to hypertension and type 2... | |
| Mouse monoclonal ARNTL2 antibody Background: BMAL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and... | |
| Mouse monoclonal ASH1L antibody Background: Probable histone-lysine N-methyltransferase ASH1L is an enzyme that in humans is encoded by the ASH1L gene. This gene encodes a member of the trithorax group... | |
| Mouse monoclonal ASH2L antibody Background: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is... | |
| Mouse monoclonal ASXL1 antibody Background: This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the... | |
| Mouse monoclonal ATE1 antibody Background: This gene encodes an arginyltransferase, an enzyme that is involved in posttranslational conjugation of arginine to N-terminal aspartate or glutamate residues. Conjugation of arginine to... | |
| Mouse monoclonal ATF3 antibody Background: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive elementbinding (CREB) protein family of transcription factors. Multiple transcript variants encoding... | |
| Mouse monoclonal ATF7IP antibody Background: ATF7IP is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an... | |
| Mouse monoclonal ATM antibody Background: The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions... | |
| Mouse monoclonal Axin1 antibody Background: Axin was originally identified as the product of the mouse gene called "fused" or fu (renamed Axin), and has since been shown to play a... | |
| Mouse monoclonal AXUD1 antibody Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and... | |
| Mouse monoclonal BACH1 antibody Background: This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad... | |
| Mouse monoclonal BAK1 antibody Background: BAK1 encodes an receptor-like kinase (RLK) with a putative extracellular domain, a single transmembrane domain, an intracellular-juxtam embrane domain, and a kinase domain. BAK1 expression... | |
| Mouse monoclonal BAP1 antibody Background: The protein encoded by this gene localizes to the nucleus and it interacts with the RING finger domain of the breast cancer 1, early onset... | |
| Mouse monoclonal BARD1 antibody Background: BARD1 interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, BARD1 shares homology with... | |
| Mouse monoclonal BAT1 antibody Background: This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an... | |
| Mouse monoclonal BAZ1B antibody Background: This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. | |
| Mouse monoclonal BBX antibody Background: The BBX gene is a transcription factor that is necessary for cell cycle progression from G1 to S phase. | |
| Mouse monoclonal BCAS3 antibody Background: Breast carcinoma amplified sequence 3, also known as BCAS3, is a protein which in humans is encoded by the BCAS3 gene. BCAS3 is a gene... | |
| Mouse monoclonal Bcl-2 antibody Background: Bcl-2 (B-cell lymphoma protein 2 alpha) is an anti-apoptotic protein located primarily in the outer mitochondrial membrane. It blocks the apoptotic death of some cells... | |
| Mouse monoclonal BCL3 antibody Background: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded... | |
| Mouse monoclonal BCL6 antibody Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor... | |
| Mouse monoclonal BCL9 antibody Background: B-cell CLL/lymphoma 9 encodes a protein that in humans is encoded by the BCL9 gene. BCL9 is associated with B-cell acute lymphoblastic leukemia. It may... | |
| Mouse monoclonal BDP1 antibody Background: TFIIIB150 is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded... | |
| Mouse monoclonal BIN1 antibody Background: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor... | |
| Mouse monoclonal BLMH antibody Background: Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation... | |
| Mouse monoclonal BMS1L antibody Background: The BMS1L gene may act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus. | |
| Mouse monoclonal BRCC36 antibody Background: BRCC36 (BRCA1/BRCA2-contain ing complex, subunit 36) is a holoenzyme complex containing BRCA1, BRCA2. BRCC36 is an ubiquitin E3 ligase complex that has a role in... | |
| Mouse monoclonal BRD1 antibody Background: This gene encodes a protein of unknown function. The protein contains a bromodomain, a sequence motif often found in transcriptional coactivators, and localizes to the... | |
| Mouse monoclonal BRD3 antibody Background: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region... | |
| Mouse monoclonal BRF1 antibody Background: This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation... | |
| Mouse monoclonal BRIP1 antibody Background: The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type... | |
| Mouse monoclonal BRPF1 antibody Background: The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and... | |
| Mouse monoclonal BTAF1 antibody Background: Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP; MIM 600075) and TBP-associated factors, or TAFs (e.g., TAF2B; MIM... | |
| Mouse monoclonal BTF3 antibody Background: This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative... | |
| Mouse monoclonal BTG1 antibody Background: This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1... | |
| Mouse monoclonal BUB1 antibody Background: BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene. Bub1 is a serine/threonine protein kinase first... | |
| Mouse monoclonal BXDC1 antibody Background: BXDC1 (Brix domain-containing protein 1) is a 306 amino acid protein encoded by the human gene BXDC1. BXDC1 is a nuclear protein that contains one... | |
| Mouse monoclonal BXDC2 antibody Background: BXDC2 is required for biogenesis of the 60S ribosomal subunit. | |
| Mouse monoclonal C14orf169 antibody Background: C14orf169 encodes a histone demethylase that specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially... | |
| Mouse monoclonal C14orf172 antibody Background: This gene is a catalytic subunit of tRNA (adenine-N(1)-)-meth yltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | |
| Mouse monoclonal CACYBP antibody Background: The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. | |
| Mouse monoclonal CAPN7 antibody Background: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The... | |
| Mouse monoclonal CARD8 antibody Background: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of... | |
| Mouse monoclonal CART1 antibody Background: The specific function of this gene has yet to be determined in humans; however, in rodents, it is necessary for survival of the forebrain mesenchyme... | |
| Mouse monoclonal Casein Kinase 1 alpha antibody Background: Caseine Kinase 1 alpha belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily. CK1 isoforms (alpha,... | |
| Mouse monoclonal CBFA2T2 antibody Background: In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric... | |
| Mouse monoclonal CBFB antibody Background: The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates... | |
| Mouse monoclonal CBL antibody Background: The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for... | |
| Mouse monoclonal CBLB antibody Background: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugatin g enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome. Negatively... | |
| Mouse monoclonal CBP antibody Background: Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 coactivator. Mediates cAMP-gene regulation by binding specifically to... | |
| Mouse monoclonal CBR3 antibody Background: Carbonyl reductase 3 (CBR3) is a member of the family of short chain dehydrogenases/reduc tases. Carbonyl reductases are two monomeric carbonyl reductases, carbonyl CBR1 and... | |
| Mouse monoclonal CCNA2 antibody Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through... | |
| Mouse monoclonal CCNB1 antibody Background: The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). | |
| Mouse monoclonal CCNB2 antibody Background: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential... | |
| Mouse monoclonal CCND3 antibody Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through... | |
| Mouse monoclonal CCNE1 antibody Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through... | |
| Mouse monoclonal CCNF antibody Background: This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent... | |
| Mouse monoclonal CCNJ antibody Background: the CCNJ gene encodes the cyclin J protein. | |
| Mouse monoclonal CCNT2 antibody Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through... | |
| Mouse monoclonal CD34 antibody Background: Hematopoietic progenitor cell antigen CD34(CD34) is a monomeric cell surface antigen with a molecular mass of approximately 110 kDa that is selectively expressed on human... | |
| Mouse monoclonal CDC2 antibody Background: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved... | |
| Mouse monoclonal CDC25C antibody Background: This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine... | |
| Mouse monoclonal CDC27 antibody Background: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein... | |
| Mouse monoclonal CDC45L antibody Background: The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA... | |
| Mouse monoclonal CDC5L antibody Background: The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M... | |
| Mouse monoclonal CDC6 antibody Background: Cdc6, or Cell Division Cycle 6, encodes a protein in eukaryotic cells that is studied in the budding yeast Saccharomyces cerevisiae. It is an essential... | |
| Mouse monoclonal CDK2AP1 antibody Background: The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting... | |
| Mouse monoclonal CDK7 antibody Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene... | |
| Mouse monoclonal CDK9 antibody Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene... | |
| Mouse monoclonal CDKN1B antibody Background: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation... | |
| Mouse monoclonal CDKN2C antibody Background: The protein encoded by this gene is a member of the INK4 family of cyclindependent kinase inhibitors. This protein has been shown to interact with... | |
| Mouse monoclonal CEBPA antibody Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can... | |
| Mouse monoclonal CEBPE antibody Background: The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also... | |
| Mouse monoclonal CENPC1 antibody Background: CENPC1 is a component of the CENPA-NAC (nucleosome-associat ed) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and... | |
| Mouse monoclonal CENPF antibody Background: This gene encodes a protein that associates with the centromere-kinetocho re complex. The protein is a component of the nuclear matrix during the G2 phase... | |
| Mouse monoclonal CHD1L antibody Background: CHD1L is a DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and... | |
| Mouse monoclonal CHD3 antibody Background: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related... | |
| Mouse monoclonal CHD6 antibody Background: Chromosomal DNA of eukaryotic cells is compacted by nuclear proteins to form chromatin, an organized nucleoprotein structure that can inhibit gene expression. Several multisubunit protein... | |
| Mouse monoclonal CHEK1 antibody Background: Chk1 encodes a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216... | |
| Mouse monoclonal CHES1 antibody Background: This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint... | |
| Mouse monoclonal CHI3L1 antibody Background: Chitinase 3-Like-1 (CHI3L1) is a recently discovered human glycoprotein which is related in amino acid sequence to the chitinase protein family, but has no chitinase... | |
| Mouse monoclonal CHTF18 antibody Background: CHTF18 is a chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader... | |
| Mouse monoclonal CIB2 antibody Background: The amino acid sequence the protein encoded by this gene is similar to that of KIP/CIB, calcineurin B, and calmodulin. This suggests that the encoded... | |
| Mouse monoclonal CIZ1 antibody Background: The CIZ1 gene encodes the Cip1-interacting zinc finger protein. | |
| Mouse monoclonal CLNS1A antibody Background: The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN)... | |
| Mouse monoclonal CLOCK antibody Background: Clock (Circadian Locomotor Output Cycles Kaput) is a gene encoding a basic-helix-loop-hel ix-PAS transcription factor (CLOCK) that affects both the persistence and period of circadian... | |
| Mouse monoclonal CNOT2 antibody Background: This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved... | |
| Mouse monoclonal CNOT3 antibody Background: The CNOT3 gene encodes the CCR4-NOT transcription complex subunit 3 protein. | |
| Mouse monoclonal CNOT6 antibody Background: The CNOT6 gene encodes the CCR4-NOT transcription complex subunit 6 protein. The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional... | |
| Mouse monoclonal COX4NB antibody Background: COX4NB is a neighbour of the COX4 reading frame. | |
| Mouse monoclonal CPSF4 antibody Background: Cleavage and polyadenylation specificity factor subunit 4 is a protein that in humans is encoded by the CPSF4 gene. Inhibition of the nuclear export of... | |
| Mouse monoclonal CPXCR1 antibody Background: The CPXCR1 gene encodes CPX chromosomal region candidate gene 1 protein. | |
| Mouse monoclonal CRABP1 antibody Background: CRABP1 (cellular retinoic acid-binding protein 1) is a member of the specific carrier proteins for members of the vitamin A family. CRABP1 is assumed to... | |
| Mouse monoclonal CREB3 antibody Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response... | |
| Mouse monoclonal CRK antibody Background: The CRK gene encodes a member of an adapter protein family that binds to several tyrosine-phosphoryla ted proteins. This protein has several SH2 and SH3... | |
| Mouse monoclonal CRNKL1 antibody Background: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This... | |
| Mouse monoclonal CRSP2 antibody Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with... | |
| Mouse monoclonal CRSP6 antibody Background: CRSP6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as... | |
| Mouse monoclonal CRSP7 antibody Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with... | |
| Mouse monoclonal CSE1L antibody Background: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation... | |
| Mouse monoclonal CSRP2BP antibody Background: CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins... | |
| Mouse monoclonal CTCF antibody Background: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF)... | |
| Mouse monoclonal CTDSP2 antibody Background: CTDSP2 preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit... | |
| Mouse monoclonal CTNND1 antibody Background: This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and althernative... | |
| Mouse monoclonal CUL3 antibody Background: This gene is involved in ubiquitination of cyclin E and, in complex with RBX1, of cyclin D1 (in vitro) thus involved in regulation of G1/S... | |
| Mouse monoclonal DBF4 antibody Background: This gene functions as a regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. | |
| Mouse monoclonal DBP antibody Background: D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene. | |
| Mouse monoclonal DCK antibody Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and... | |
| Mouse monoclonal DDB2 antibody Background: The DDB2 gene plays a role in DNA repair by forming with DDB1 the UV-damaged DNA-binding protein complex (UV-DDB). Binds to pyrimidine dimers. Component of... | |
| Mouse monoclonal DDX27 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration... | |
| Mouse monoclonal DDX39 antibody Background: This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp- Glu-Ala-Asp (DEAD) and are putative... | |
| Mouse monoclonal DDX3X antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration... | |
| Mouse monoclonal DDX41 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration... | |
| Mouse monoclonal DDX47 antibody Background: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. | |
| Mouse monoclonal DDX48 antibody Background: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. | |
| Mouse monoclonal DDX5 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration... | |
| Mouse monoclonal DDX50 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration... | |
| Mouse monoclonal DEAF1 antibody Background: This gene is a transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1... | |
| Mouse monoclonal DELGEF antibody Background: DelGEF is an RCC1-related protein encoded by a gene on chromosome 11p14 critical for two forms of hereditary deafness. | |
| Mouse monoclonal DFFB antibody Background: DNA fragmentation factor subunit beta is a protein that in humans is encoded by the DFFB gene. Apoptosis is a cell death process that removes... | |
| Mouse monoclonal DGCR14 antibody Background: This gene is located within the minimal DGS critical region (MDGCR) thought to contain the gene(s) responsible for a group of developmental disorders. These disorders... | |
| Mouse monoclonal DHX29 antibody Background: DHX29 encodes an ATP-binding RNA helicase involved in translation initiation. Required for efficient initiation on mammalian mRNAs with structured 5'-UTRs by promoting efficient NTPase-dependent 48S... | |
| Mouse monoclonal DHX38 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration... | |
| Mouse monoclonal DHX9 antibody Background: This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded... | |
| Mouse monoclonal DLX4 antibody Background: Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family... | |
| Mouse monoclonal DMAP1 antibody Background: This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and... | |
| Mouse monoclonal DMTF1 antibody Background: This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N-... | |
| Mouse monoclonal DNMT3B antibody Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X chromosome inactivation. Studies in mice have demonstrated that DNA methylation... | |
| Mouse monoclonal DNTTIP1 antibody Background: DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltran sferase, a DNA polymerase that catalyzes the polymerization of DNA in the absence of a... | |
| Mouse monoclonal DUSP4 antibody Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both... | |
| Mouse monoclonal DUSP5 antibody Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both... | |
| Mouse monoclonal E2F1 antibody Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the... | |
| Mouse monoclonal E2F2 antibody Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the... | |
| Mouse monoclonal E2F5 antibody Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the... | |
| Mouse monoclonal E2F6 antibody Background: This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle... | |
| Mouse monoclonal EEA1 antibody Background: This gene binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. | |
| Mouse monoclonal EGLN1 antibody Background: PHD1 (Egln2), PHD-2 (Egln1), and PHD3 (Egln3) are members of the Egln family of proline hydroxylases. The EGLN family, which are known to be cellular... | |
| Mouse monoclonal EHMT1 antibody Background: Histone methyltransferase. Methylates 'Lys-9' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to... | |
| Mouse monoclonal EIF2S1 antibody Background: The translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. | |
| Mouse monoclonal EIF3S12 antibody Background: Eukaryotic translation initiation factor 3 subunit K is a protein that in humans is encoded by the EIF3K gene. The 700 kDa eukaryotic translation initiation... | |
| Mouse monoclonal EIF4ENIF1 antibody Background: The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta... | |
| Mouse monoclonal EIF5A antibody Background: EIF5A, previously known as EIF4D and IF-M2Ba, is a highly conserved 17-kDa protein that was originally characterized as a translation initiation factor, promoting the formation... | |
| Mouse monoclonal ELF2 antibody Background: Isoform 1 of this gene transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter, Isoform 2 may... | |
| Mouse monoclonal ELF3 antibody Background: ELF3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the... | |
| Mouse monoclonal ELL antibody Background: The ELL gene has been shown to interact with P53, a tumor suppressor protein. | |
| Mouse monoclonal ELL2 antibody Background: ELL2 is an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple... | |
| Mouse monoclonal EP300 antibody Background: EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CBP (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]),... | |
| Mouse monoclonal EPHX1 antibody Background: Epoxide hydrolase 1 (EPHX1) is a family of biotransformation enzymes which are involved in the hydrolysis of various epoxides and epoxide intermediates. Epoxide hydrolase plays... | |
| Mouse monoclonal EPM2A antibody Background: This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this... | |
| Mouse monoclonal ERCC1 antibody Background: This gene encodes a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. | |
| Mouse monoclonal ERCC3 antibody Background: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa... | |
| Mouse monoclonal ERCC5 antibody Background: Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause... | |
| Mouse monoclonal ERCC6 antibody Background: This gene encodes a DNA-binding protein that is important in transcription-couple d excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting... | |
| Mouse monoclonal ERCC8 antibody Background: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA... | |
| Mouse monoclonal ETV3 antibody Background: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity{EC1}. | |
| Mouse monoclonal ETV5 antibody Background: This gene binds to DNA sequences containing the consensus nucleotide core sequence GGAA. | |
| Mouse monoclonal EVI1 antibody Background: Ecotropic viral integration site 1 is a human protein encoded by the EVI1 gene. EVI1 was first identified as a common retroviral integration site in... | |
| Mouse monoclonal EXOSC2 antibody Background: Mammalian mRNAs contain AU-rich elements (AREs) within their three prime untranslated regions. In yeast, 3-prime-to-5-prime mRNA degradation is mediated by the exosome, a multisubunit particle. | |
| Mouse monoclonal EXOSC7 antibody Background: EXOSC7 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated... | |
| Mouse monoclonal EXOSC8 antibody Background: This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is... | |
| Mouse monoclonal EXOSC9 antibody Background: EXOSC9 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. | |
| Mouse monoclonal FALZ antibody Background: This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis... | |
| Mouse monoclonal FANCA antibody Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group... | |
| Mouse monoclonal FANCE antibody Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. Fanconi anemia is a... | |
| Mouse monoclonal FBL antibody Background: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. | |
| Mouse monoclonal FBXL4 antibody Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins... | |
| Mouse monoclonal FBXO18 antibody Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The... | |
| Mouse monoclonal FER antibody Background: Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface... | |
| Mouse monoclonal FKBP14 antibody Background: The FK506-binding proteins (FKBPs) are a unique group of chaperones found in a wide variety of organisms. The gene encoding FKBP14 maps to human chromosome... | |
| Mouse monoclonal FKBP3 antibody Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving... | |
| Mouse monoclonal FkBP4 antibody Background: FkBP4, also known as FkBP52, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein... | |
| Mouse monoclonal FMNL1 antibody Background: This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but... | |
| Mouse monoclonal FOS antibody Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of... | |
| Mouse monoclonal FOXL2 antibody Background: This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations... | |
| Mouse monoclonal FOXM1 antibody Background: The FOXM1 gene is a transcriptional activatory factor. It may also play a role in the control of cell proliferation. | |
| Mouse monoclonal FOXO1A antibody Background: FOXO1 belongs to the forkhead family of transcription factors that are characterized by a distinct fork head domain. The specific function of this gene has... | |
| Mouse monoclonal FTSJ2 antibody Background: The protein encoded by this gene is a member of the S-adenosylmethionine -binding protein family. It is a nucleolar protein and it may be involved... | |
| Mouse monoclonal FUS2 antibody Background: Vertebrate FUS2 genes, which are known to be putative tumor suppressor genes, contain several important domains such as the catalytic N-acetyltransferase (NAT) domain. NAT domain... | |
| Mouse monoclonal G10 antibody Background: The protein encoded by this gene has been found to be highly conserved in a wide range of eukaryotic species. The function of G10 is... | |
| Mouse monoclonal G6PD antibody Background: Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level... | |
| Mouse monoclonal GABPA antibody Background: This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit... | |
| Mouse monoclonal GAPDH antibody Background: Multiple roles for glyceraldehyde-3-pho sphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and... | |
| Mouse monoclonal GARNL1 antibody Background: This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds... | |
| Mouse monoclonal GAS7 antibody Background: Growth arrest-specific 7, also known as GAS7, is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a... | |
| Mouse monoclonal GATAD1 antibody Background: The protein encoded by this gene is associated with ocular development. | |
| Mouse monoclonal GCN5L2 antibody Background: GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation to provide the additional components important for acetylation. GCN5L2 can... | |
| Mouse monoclonal GFP antibody Background: GFP, also known as green fluorescent protein, is a protein produced by the jellyfish (Aequorea Victoria) that emits bioluminescence in the green zone of the... | |
| Mouse monoclonal GMEB2 antibody Background: This gene is a member of KDWK gene family. The product of this gene associates with GMEB1 protein, and the complex is essential for parvovirus... | |
| Mouse monoclonal GOLGB1 antibody Background: GOLGB1 has been shown to interact with ACBD3, which plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. | |
| Mouse monoclonal GPC4 antibody Background: The glypican (Gpc) family of cell surface heparan sulfate proteoglycans is expressed in a tissue specific and developmentally regulated fashion. Expression of glypican 4 has... | |
| Mouse monoclonal GRLF1 antibody Background: The human glucocorticoid receptor DNA binding factor, which associates with the promoter region of the glucocorticoid receptor gene (hGR gene), is a repressor of glucocorticoid... | |
| Mouse monoclonal GTF2A1 antibody Background: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II and several general initiation factors. One of these factors... | |
| Mouse monoclonal GTF2B antibody Background: This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to... | |
| Mouse monoclonal GTF2E1 antibody Background: This gene recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH... | |
| Mouse monoclonal GTF2E2 antibody Background: GTF2E2 recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and... | |
| Mouse monoclonal GTF2H1 antibody Background: GTF2H1 is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA... | |
| Mouse monoclonal GTF2H2 antibody Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which... | |
| Mouse monoclonal GTF2H4 antibody Background: GTF2H4 is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA... | |
| Mouse monoclonal GTF2IRD1 antibody Background: The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to... | |
| Mouse monoclonal GTF3C2 antibody Background: GTF3C2 is required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S... | |
| Mouse monoclonal HAND2 antibody Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family... | |
| Mouse monoclonal HARS antibody Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme... | |
| Mouse monoclonal HAX1 antibody Background: HAX1 is known to associate with hematopoietic cell-specific Lyn substrate 1 (HS1), one of the substrates of receptor-coupled tyrosine kinases activated during clonal expansion and... | |
| Mouse monoclonal HCCA2 antibody Background: This gene stimulates the autophosphorylation and kinase activity of STK38 and STK38L. | |
| Mouse monoclonal HCFC2 antibody Background: This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and... | |
| Mouse monoclonal HD antibody Background: Huntingtin is a disease gene linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by... | |
| Mouse monoclonal HDAC1 antibody Background: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene... | |
| Mouse monoclonal HDGF antibody Background: This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in... | |
| Mouse monoclonal HDLBP antibody Background: High density lipoprotein-binding protein, also known as vigilin, is a 110 kDa protein that specifically binds HDL molecules and may function in the removal of... | |
| Mouse monoclonal HEL308 antibody Background: HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase. | |
| Mouse monoclonal HEXIM1 antibody Background: This gene is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a... | |
| Mouse monoclonal HEYL antibody Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded... | |
| Mouse monoclonal HHEX antibody Background: This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages... | |
| Mouse monoclonal HHV8 antibody Background: ORF73 protein of human herpesvirus 8 (HHV-8) is a kaposi's sarcoma-associated herpesvirus (kSHV) latent protein which has been suspected of playing a crucial role in... | |
| Mouse monoclonal HIP/ST13 antibody Background: HIP(Hsc70-interactin g protein), also known as ST13, is a co-chaperone to the major heat shock proteins, HSP70 and HSP90, and appears in early receptor complexes. | |
| Mouse monoclonal HIP2 antibody Background: The protein encoded by this gene belongs to the ubiquitin-conjugatin g enzyme family. It binds selectively to a large region at the N terminus of... | |
| Mouse monoclonal HIRIP3 antibody Background: The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural... | |
| Mouse monoclonal HIVEP1 antibody Background: Members of the ZAS family, such as ZAS1 (HIVEP1), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair... | |
| Mouse monoclonal HIVEP2 antibody Background: Members of the ZAS family, such as ZAS2 (HIVEP2), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair... | |
| Mouse monoclonal HMG2L1 antibody Background: HMG2L1 is a member of the High mobility group (HMG) group of proteins, which are nonhistone chromosomal proteins. | |
| Mouse monoclonal HMGA2 antibody Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are... | |
| Mouse monoclonal Homer1 antibody Background: Homer1 (Homer protein homolog 1) belongs to the Homer family of proteins that regulate signal transduction through, and the trafficking of, glutamate receptors, as well... | |
| Mouse monoclonal HOXA11 antibody Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four... | |
| Mouse monoclonal HOXA5 antibody Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four... | |
| Mouse monoclonal HOXA7 antibody Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four... | |
| Mouse monoclonal HOXA9 antibody Background: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four... | |
| Mouse monoclonal HOXB5 antibody Background: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a... | |
| Mouse monoclonal HOXB7 antibody Background: This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster... | |
| Mouse monoclonal HOXC11 antibody Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role... | |
| Mouse monoclonal HOXC9 antibody Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role... | |
| Mouse monoclonal HR antibody Background: This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid... | |
| Mouse monoclonal HRB2 antibody Background: HRB2 is required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | |
| Mouse monoclonal HSF2 antibody Background: HSF2, as well as the related gene HSF1, encodes a protein that binds specifically to the heat-shock element and has homology to HSFs of other... | |
| Mouse monoclonal HSPA1L antibody Background: This gene encodes a 70 kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates... | |
| Mouse monoclonal HTATIP antibody Background: The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. | |
| Mouse monoclonal ID1 antibody Background: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. | |
| Mouse monoclonal ID2 antibody Background: The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix... | |
| Mouse monoclonal IL32 antibody Background: The gene encoding IL32 is located on human chromosome 16p13.3 and is organized into eight exons. IL32 is mainly expressed in natural killer cells, T... | |
| Mouse monoclonal IRF1 antibody Background: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and... | |
| Mouse monoclonal IRF3 antibody Background: IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that... | |
| Mouse monoclonal IRX3 antibody Background: IRX3 is a transcription factor involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the... | |
| Mouse monoclonal IRX5 antibody Background: IRX5 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos. | |
| Mouse monoclonal JARID1B antibody Background: Lysine-specific demethylase 5B also known as histone demethylase JARID1B is a demethylase enzyme that in humans is encoded by the KDM5B gene. | |
| Mouse monoclonal JMJD2A antibody Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H... | |
| Mouse monoclonal JUNB antibody Background: Transcription factor jun-B is a protein that in humans is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating... | |
| Mouse monoclonal KCTD15 antibody Background: KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZ domain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15 gene. | |
| Mouse monoclonal KIF22 antibody Background: The protein encoded by this gene is a member of kinesin-like protein family. This family of proteins are microtubuledependent molecular motors that transport organelles within... | |
| Mouse monoclonal KIF2C antibody Background: The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubuledependent molecular motors that transport organelles within... | |
| Mouse monoclonal KIN antibody Background: The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell... | |
| Mouse monoclonal KLF11 antibody Background: Transcriptional factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding sites... | |
| Mouse monoclonal KLF3 antibody Background: KLF3 binds to the CACCC box of erythroid cell-expressed genes. KLF3 may play a role in hematopoiesis. | |
| Mouse monoclonal KNTC2 antibody Background: HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned... | |
| Mouse monoclonal KPNA1 antibody Background: Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other... | |
| Mouse monoclonal KPNA4 antibody Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that... | |
| Mouse monoclonal KPNB1 antibody Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear... | |
| Mouse monoclonal KRT18 antibody Background: Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins... | |
| Mouse monoclonal LDHA antibody Background: Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR... | |
| Mouse monoclonal LDOC1 antibody Background: The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein... | |
| Mouse monoclonal LHX2 antibody Background: This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteinerich zinc-binding domain. The encoded... | |
| Mouse monoclonal LHX4 antibody Background: This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc binding domain. The encoded protein is... | |
| Mouse monoclonal LITAF antibody Background: Lipopolysaccharide-i nduced tumor necrosis factor-alpha factor (LITAF) mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-i nduced processes. LITAF binds to STAT6B, a... | |
| Mouse monoclonal LMAN2 antibody Background: This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds... | |
| Mouse monoclonal LMO1 antibody Background: LMO1 enocdes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in... | |
| Mouse monoclonal LSM10 antibody Background: The protein encoded by the LSM10 gene binds specifically to U7 snRNA. | |
| Mouse monoclonal LSM8 antibody Background: This gene is a member of the LSm family and encodes a protein with a closed barrel shape, made up of five anti-parallel beta strands... | |
| Mouse monoclonal LTA antibody Background: Lymphotoxin-alpha (LT-alpha; LTA) is member of the TNF ligand superfamily, binding the same TNF receptor and mediating similar pleiotropic effects. LTA, located within the MHC... | |
| Mouse monoclonal MAD1 antibody Background: MAD1 dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex,... | |
| Mouse monoclonal MAML3 antibody Background: MAML3 Acts as a transcriptional coactivator for NOTCH proteins and has been shown to amplify NOTCH-induced transcription of HES1. | |
| Mouse monoclonal MAPK1 antibody Background: Mitogen-activated protein kinases (MAPKs) are reported to be critical regulatory factors for the growth and migration of various cell types including vascular smooth muscle cells... | |
| Mouse monoclonal MAPK3 antibody Background: Mitogen-activated protein kinase (MAPKs) are a widely conserved family of serine/threonine kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. | |
| Mouse monoclonal MARS antibody Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene belongs to the class... | |
| Mouse monoclonal Maspin antibody Background: Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It... | |
| Mouse monoclonal MAT2A antibody Background: Methionine adenosyltransferase II (MAT II) is a key enzyme in cellular metabolism and catalyzes the formation of S-adenosylmethionine (SAMe) from L-methionine and ATP. MAT2A is... | |
| Mouse monoclonal MATR3 antibody Background: The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear... | |
| Mouse monoclonal MAX antibody Background: Protein max is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with... | |
| Mouse monoclonal MAZ antibody Background: MAZ (gene) has been shown to interact with BPTF, which is associated with Alzheimer's and other neurodegenerative diseases. | |
| Mouse monoclonal MCM2 antibody Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome... | |
| Mouse monoclonal MEIS2 antibody Background: This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containi ng proteins. TALE homeobox proteins are highly... | |
| Mouse monoclonal MGA antibody Background: This gene functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an... | |
| Mouse monoclonal MINCLE antibody Background: MINCLE (macrophage inducible C-type lectin, also called CLEC4E or CLECSF9), which is a diverse family of proteins which was originally defined by their ability to... | |
| Mouse monoclonal MNT antibody Background: The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of... | |
| Mouse monoclonal MTA2 antibody Background: This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human... | |
| Mouse monoclonal MTA3 antibody Background: MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependen t manner, and thus... | |
| Mouse monoclonal MXI1 antibody Background: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The... | |
| Mouse monoclonal MYBL2 antibody Background: The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. | |
| Mouse monoclonal MYCN antibody Background: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the... | |
| Mouse monoclonal MYL2 antibody Background: Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the... | |
| Mouse monoclonal NAB1 antibody Background: This gene acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2 . | |
| Mouse monoclonal NAP1L1 antibody Background: This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating... | |
| Mouse monoclonal NARG1 antibody Background: This gene encodes a protein of unknown function. However, similarity to proteins in yeast and other species suggests that this protein may be an N-acetyltransferase. | |
| Mouse monoclonal NARS antibody Background: Aminoacy1-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginy1-tRNA synthetase is localized to the cytoplasm and belongs to... | |
| Mouse monoclonal NCKIPSD antibody Background: The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the... | |
| Mouse monoclonal NCOA1 antibody Background: The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor... | |
| Mouse monoclonal NCOA2 antibody Background: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1). Required with... | |
| Mouse monoclonal NCOA3 antibody Background: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded... | |
| Mouse monoclonal NEIL2 antibody Background: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by... | |
| Mouse monoclonal NEIL3 antibody Background: NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by... | |
| Mouse monoclonal NEK4 antibody Background: This gene seems to act exclusively upon threonine residues (By similarity). | |
| Mouse monoclonal NET1 antibody Background: NET1 acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. It may also be involved in activation of the SAPK/JNK pathway. | |
| Mouse monoclonal NFATC3 antibody Background: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least... | |
| Mouse monoclonal NFE2L2 antibody Background: Nuclear factor (erythroid-derived 2)-like 2, also known as NFE2L2 or Nrf2, is a transcription factor that in humans is encoded by the NFE2L2 gene. Nrf2... | |
| Mouse monoclonal NFIA antibody Background: Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors... | |
| Mouse monoclonal NFIB antibody Background: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 ' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These... | |
| Mouse monoclonal NFIC antibody Background: NFIC recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 ' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. | |
| Mouse monoclonal NFKB2 antibody Background: NF-kappa-B has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and... | |
| Mouse monoclonal NFKBIA antibody Background: NFKBIA ihibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation... | |
| Mouse monoclonal NFRKB antibody Background: The protein encoded by NFRKB binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. | |
| Mouse monoclonal NFS1 antibody Background: Iron-sulfur clusters are required for the function of many cellular enzymes. The protein encoded by this gene supplies inorganic sulfur to these clusters by removing... | |
| Mouse monoclonal NFYB antibody Background: The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to... | |
| Mouse monoclonal Nicastrin antibody Background: Nicastrin is a large protein that is a component of an enzyme called gamma-secretase, which is lodged in the cell's membrane. Nicastrin protein is physically... | |
| Mouse monoclonal NKX3-1 antibody Background: The homeodomain-containi ng transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A... | |
| Mouse monoclonal NMNAT1 antibody Background: Nicotinamide mononucleotide adenylyltransferase 1 is an enzyme that in humans is encoded by the NMNAT1 gene. It is an essential enzyme because it catalyzes the... | |
| Mouse monoclonal NPAT antibody Background: NPAT (gene) has been shown to interact with Glyceraldehyde 3-phosphate dehydrogenase and POU2F1. | |
| Mouse monoclonal NQO2 antibody Background: Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also... | |
| Mouse monoclonal NR1H3 antibody Background: The liver X receptors, LXRA and LXRB (NR1H2; MIM 600380), form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function,... | |
| Mouse monoclonal NR2C1 antibody Background: This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding... | |
| Mouse monoclonal NR2F1 antibody Background: Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to... | |
| Mouse monoclonal NR4A1 antibody Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested... | |
| Mouse monoclonal NR4A2 antibody Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have... | |
| Mouse monoclonal NRBF2 antibody Background: This gene may modulate transcriptional activation by target nuclear receptors. It can act as transcriptional activator (in vitro). | |
| Mouse monoclonal NRIP1 antibody Background: Nuclear receptor interacting protein 1 (NRIP1) is a nuclear protein that specifically interacts with the hormone dependent activation domain AF2 of nuclear receptors. Also known... | |
| Mouse monoclonal NSD1 antibody Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a... | |
| Mouse monoclonal NTHL1 antibody Background: DNA N-glycosylases, or apurinic/apyrimidini c lyases, of the endonuclease III family, such as NTHL1, initiate DNA base excision repair of oxidized ring saturated pyrimidine residues. | |
| Mouse monoclonal NUDT21 antibody Background: The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the... | |
| Mouse monoclonal NUFIP1 antibody Background: The NUFIP1 gene encodes the nuclear fragile X mental retardation-interact ing protein, NUFIP1 has also been shown to interact with FMR1, Cyclin T1 and BRCA1. | |
| Mouse monoclonal NUP93 antibody Background: NUP93 is part of the nucleoporin complex; required for correct nuclear pore assembly. | |
| Mouse monoclonal OAT antibody Background: OAT is a 49-kDa nucleus-encoded protein imported into mitochondria to give the mature 48-kDa OAT polypeptide. It has been described in humans, animals, insects, plants... | |
| Mouse monoclonal ORC6L antibody Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies... | |
| Mouse monoclonal p66alpha antibody Background: p66 Alpha gene has a pro-apoptotic role in human cell lines and it is activated by a p53-independent pathway. | |
| Mouse monoclonal PA2G4 antibody Background: This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in... | |
| Mouse monoclonal PAX3 antibody Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain... | |
| Mouse monoclonal PAX6 antibody Background: This gene encodes paired box gene 6, one of many human homologues of the Drosophila melanogaster gene prd. In addition to the hallmark feature of... | |
| Mouse monoclonal PAX7 antibody Background: Pax-7 plays a role in neural crest development and gastrulation, and it is an important factor in the expression of neural crest markers such as... | |
| Mouse monoclonal PAX8 antibody Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a... | |
| Mouse monoclonal PBX1 antibody Background: The protein encoded by this gene binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent... | |
| Mouse monoclonal PCGF4 antibody Background: PCGF4 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including... | |
| Mouse monoclonal PCNP antibody Background: This gene may be involved in cell cycle regulation. | |
| Mouse monoclonal PDK1 antibody Background: PDK1 (pyruvate dehydrogenase kinase isoform 1) is involved in the regulation of enzymatic activity of mammalian pyruvate dehydrogenase (PDH) that is a part of a... | |
| Mouse monoclonal PER1 antibody Background: This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian... | |
| Mouse monoclonal PHF1 antibody Background: This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression... | |
| Mouse monoclonal PHTF1 antibody Background: Yhis gene may play a role in transcription regulation. | |
| Mouse monoclonal PIR antibody Background: This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and... | |
| Mouse monoclonal PKM2 antibody Background: PKM2 (pyruvate kinase M2), its association with phospho-tyrosine (pTyr) motifs, enables cells to use predominantly aerobic glycolysis instead of oxidative phosphorylation. Also this change may... | |
| Mouse monoclonal POLA2 antibody Background: This gene may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication... | |
| Mouse monoclonal POLD1 antibody Background: This gene possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with... | |
| Mouse monoclonal POLD2 antibody Background: the POLD2 gene encodes DNA polymerase delta subunit 2 enzyme . It is a component of the DNA polymerase delta complex. | |
| Mouse monoclonal POLR1D antibody Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and... | |
| Mouse monoclonal POLR2F antibody Background: This gene encodes the sixth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes, that is also shared by... | |
| Mouse monoclonal POLR2G antibody Background: The homeodomain-containi ng transcription factor NKX3A is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3A... | |
| Mouse monoclonal POLS antibody Background: The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required... | |
| Mouse monoclonal POU2F1 antibody Background: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes... | |
| Mouse monoclonal PPARA antibody Background: Peroxisome proliferator-activat ed receptor alpha (PPARalpha) is a member of the nuclear receptor family of ligand-activated transcription factors that heterodimerize with the retinoic X receptor... | |
| Mouse monoclonal PPARGC1A antibody Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits... | |
| Mouse monoclonal PPIF antibody Background: Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-transisomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. | |
| Mouse monoclonal PPP1R13L antibody Background: PPP1R13L is a regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. It also... | |
| Mouse monoclonal PRDX1 antibody Background: PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. This protein is also known to be... | |
| Mouse monoclonal PRKAR1A antibody Background: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMPdependent protein kinase (AMPK), which transduces... | |
| Mouse monoclonal PRKRA antibody Background: this gene appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor . Activates EIF2AK2 in absence of double... | |
| Mouse monoclonal PRMT2 antibody Background: PRMT2 probably methylates the guanidino nitrogens of arginyl residues in some proteins. May play a role in transcriptional coactivation. | |
| Mouse monoclonal PRPF8 antibody Background: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found... | |
| Mouse monoclonal PSMC5 antibody Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The... | |
| Mouse monoclonal PSMD11 antibody Background: PSMD11 (Proteasome 26S non-ATPase subunit 11), also known as S9, Rpn6 or p44.5, has multi-subunit protease complexes consisting of 20S subunits composed of four seven-numbered... | |
| Mouse monoclonal PWP1 antibody Background: PWP1 is a gene that encodes the periodic tryptophan protein 1 homolog. | |
| Mouse monoclonal PYGO2 antibody Background: This gene is involved in signal transduction through the Wnt pathway | |
| Mouse monoclonal RAD23B antibody Background: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). | |
| Mouse monoclonal RARG antibody Background: Retinoic acid receptors (RARs), such as RARG, are nuclear hormone receptors that act as ligand-dependent transcriptional regulators. In their liganded state, RARs activate transcription, whereas... | |
| Mouse monoclonal RB1 antibody Background: Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs... | |
| Mouse monoclonal RBPSUH antibody Background: RBPSUH is a transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum... | |
| Mouse monoclonal RELA antibody Background: NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50... | |
| Mouse monoclonal RERE antibody Background: This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in... | |
| Mouse monoclonal REXO2 antibody Background: Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN... | |
| Mouse monoclonal RFXAP antibody Background: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded... | |
| Mouse monoclonal RHOB antibody Background: RHOB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. | |
| Mouse monoclonal RNH1 antibody Background: Ribonuclease inhibitor 1 (RNH1) the placental ribonuclease inhibitor, is an acid protein with a molecular weight of 50 kDa. RNH1 is a member of a... | |
| Mouse monoclonal RORC antibody Background: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific... | |
| Mouse monoclonal RPA1 antibody Background: Replication protein A1 functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA... | |
| Mouse monoclonal RPA2 antibody Background: RPA2 functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it... | |
| Mouse monoclonal RPP30 antibody Background: RPP30 is a component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. | |
| Mouse monoclonal RUNX1 antibody Background: RUNX1 is a eukaryotic gene and the protein encoded by this gene is a transcription factor associated with M2 AML, a type of leukemia. It... | |
| Mouse monoclonal RUNX3 antibody Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex... | |
| Mouse monoclonal RUVBL1 antibody Background: This gene possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in... | |
| Mouse monoclonal SAS10 antibody Background: The SAS10 gene is essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By... | |
| Mouse monoclonal SATB2 antibody Background: May play an important role in palate formation. | |
| Mouse monoclonal SCAND1 antibody Background: The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs... | |
| Mouse monoclonal SCML2 antibody Background: Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout... | |
| Mouse monoclonal SCYE1 antibody Background: The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive... | |
| Mouse monoclonal SECISBP2 antibody Background: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteinespecif ic translation... | |
| Mouse monoclonal SLC30A9 antibody Background: SLC30A9 plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Also plays a role in transcriptional... | |
| Mouse monoclonal SMAD1 antibody Background: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against... | |
| Mouse monoclonal SMAD4 antibody Background: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in... | |
| Mouse monoclonal SMARCA4 antibody Background: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members... | |
| Mouse monoclonal SNAPC1 antibody Background: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element... | |
| Mouse monoclonal SNAPC4 antibody Background: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element... | |
| Mouse monoclonal SNRPD1 antibody Background: This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to... | |
| Mouse monoclonal SOX12 antibody Background: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG... | |
| Mouse monoclonal SOX4 antibody Background: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the... | |
| Mouse monoclonal SP1 antibody Background: Sp1, also known as Specificity Protein 1, is a human transcription factor involved in gene expression in the early development of an organism. It belongs... | |
| Mouse monoclonal STAT3 antibody Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are... | |
| Mouse monoclonal STAT5B antibody Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family... | |
| Mouse monoclonal STAT6 antibody Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family... | |
| Mouse monoclonal STK17A antibody Background: This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The... | |
| Mouse monoclonal STK3 antibody Background: Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosisinducing agents. This protein kinase activation presumably... | |
| Mouse monoclonal SUMO2 antibody Background: SUMO (small ubiquitin-related modifier) is the best-characterized member of a growing family of ubiquitin-related proteins. 8-11 kDa that covalently modify various intracellular proteins. It resembles... | |
| Mouse monoclonal SUPT4H1 antibody Background: SUPT4H1 is a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II. DSIF positively... | |
| Mouse monoclonal TADA3L antibody Background: Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at... | |
| Mouse monoclonal TAF13 antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TAF15 antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TAF4 antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TAF4B antibody Background: TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which... | |
| Mouse monoclonal TAF5 antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TAF6 antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TAF9L antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TARS antibody Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained... | |
| Mouse monoclonal TAX1BP1 antibody Background: TAX1BP1 inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the... | |
| Mouse monoclonal TBCA antibody Background: Tubulin folding cofactor A, also known as TBCA, is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to... | |
| Mouse monoclonal TBP antibody Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID... | |
| Mouse monoclonal TCEA1 antibody Background: This gene is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping... | |
| Mouse monoclonal TCEA3 antibody Background: This gene is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping... | |
| Mouse monoclonal TCERG1 antibody Background: This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase... | |
| Mouse monoclonal TCF8 antibody Background: TCF8 encodes a human zinc finger transcription factor that represses T-lymphocyte-specifi c IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime... | |
| Mouse monoclonal TDP1 antibody Background: Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. | |
| Mouse monoclonal TEAD1 antibody Background: This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide... | |
| Mouse monoclonal TEAD2 antibody Background: TEAD2 is a putative transcription factor that binds to the SPH and GT-IIC "enhansons" (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. | |
| Mouse monoclonal TFAP2A antibody Background: AP2-alpha is a 52kDa retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein... | |
| Mouse monoclonal TFAP2C antibody Background: The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act... | |
| Mouse monoclonal TFAP4 antibody Background: Transcription factors of the basic helix-loop-helix-zip per (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which... | |
| Mouse monoclonal TFDP2 antibody Background: The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation... | |
| Mouse monoclonal TFEB antibody Background: Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3... | |
| Mouse monoclonal TGIF antibody Background: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly... | |
| Mouse monoclonal TGM4 antibody Background: TGM4 (Transglutaminase 4; also TGP and Prostate-specific transglutaminase) is a 77kDa member of the papain-like family of transglutaminases. TGM4 is a unique member of the... | |
| Mouse monoclonal THOC1 antibody Background: THOC1 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. | |
| Mouse monoclonal THRA antibody Background: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has... | |
| Mouse monoclonal TNPO3 antibody Background: TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins, which are essential precursor-mRNA splicing factors. | |
| Mouse monoclonal TOE1 antibody Background: TOE1 inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. | |
| Mouse monoclonal TPX2 antibody Background: TPX2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or... | |
| Mouse monoclonal TRIM28 antibody Background: The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes... | |
| Mouse monoclonal TRIOBP antibody Background: This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell... | |
| Mouse monoclonal TRIP13 antibody Background: This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand... | |
| Mouse monoclonal TSNAX antibody Background: This gene encodes a protein which specifically interacts with translin, a DNA-binding protein that binds consensus sequences at breakpoint junctions of chromosomal translocations. The encoded... | |
| Mouse monoclonal TTC35 antibody Background: the TTC35 gene encodes the sequence for the tetratricopeptide repeat 35 protein. | |
| Mouse monoclonal TTR antibody Background: TTR encodes transthyretin, a circulating and abundant tetramer that functions as a carrier protein of thyroid hormone and retinol binding protein. Transthyretin(TTR) is mainly produced... | |
| Mouse monoclonal TUBB2b antibody Background: The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. Multiple beta tubulin... | |
| Mouse monoclonal TUBD1 antibody Background: In the elongating spermatid TUBD1 is associated with the manchette, a specialized microtubule system present during reshaping of the sperm head. | |
| Mouse monoclonal TUPLE1 antibody Background: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are... | |
| Mouse monoclonal TWIST antibody Background: Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor... | |
| Mouse monoclonal TYMS antibody Background: The methylation of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dMTP) is an essential step for the formation of thymine nucleotides. This process is catalyzed by... | |
| Mouse monoclonal UBE2A antibody Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes... | |
| Mouse monoclonal UBE2S antibody Background: UBE2S, also known as ubiquitin-conjugatin g enzyme E2S, is a member of the ubiquitin-conjugatin g enzyme family. This protein is able to form a thiol... | |
| Mouse monoclonal UBN1 antibody Background: UBN1 acts as a novel regulator of senescence. Involved in the formation of senescence-associate d heterochromatin foci (SAHF), which represses expression of proliferation-promot ing genes. | |
| Mouse monoclonal UBP1 antibody Background: UBP1 functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in... | |
| Mouse monoclonal USF2 antibody Background: This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate... | |
| Mouse monoclonal VARS1 antibody Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained... | |
| Mouse monoclonal VAX2 antibody Background: VAX2 gene was named based on its high seqeunce similarity to VAX1 gene and is almost exclusively expressed in the ventral portion of the retina... | |
| Mouse monoclonal VDR antibody Background: This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The... | |
| Mouse monoclonal XBP1 antibody Background: This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This... | |
| Mouse monoclonal XPOT antibody Background: This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA... | |
| Mouse monoclonal XRCC5 antibody Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATPdependant DNA helicase II or... | |
| Mouse monoclonal XRCC6 antibody Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a... | |
| Mouse monoclonal YARS antibody Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained... | |
| Mouse monoclonal YEATS4 antibody Background: YEATS4 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal... | |
| Mouse monoclonal YY1 antibody Background: YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a... | |
| Mouse monoclonal ZFP36L1 antibody Background: This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester... | |
| Mouse monoclonal ZNF136 antibody Background: This gene may be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing... | |
| Mouse monoclonal ZNF161 antibody Background: Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is... | |
| Mouse monoclonal ZNF174 antibody Background: ZNF174 may be involved in the repression of transcription. | |
| Mouse monoclonal ZNF19 antibody Background: The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a... | |
| Mouse monoclonal ZNF281 antibody Background: ZNF281 is involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in... | |
| Mouse monoclonal ZNF3 antibody Background: The ZNF3 gene is involved in cell differentiation and/or proliferation. | |
| Mouse monoclonal ZNF35 antibody Background: ZNF35 may be involved in transcriptional regulation. Involved in cell differentiation and/or proliferation. | |
| Mouse monoclonal ZNF354A antibody Background: The protein encoded by ZNF354A has been shown to exist at transcript level. | |
| Mouse monoclonal ZNF37A antibody Background: This gene may be involved in transcriptional regulation. | |
| Mouse monoclonal ZNF38 antibody Background: ZNF38 is a strong transcriptional activator (By similarity). | |
| Mouse monoclonal ZNF384 antibody Background: This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in... | |
| Mouse monoclonal ZNF44 antibody Background: ZNF444 has a domain structure and amino acid sequence similar to several zinc finger transcription factors, such as Kruppel-like ZNF191 (MIM 194534). | |
| Mouse monoclonal ZNF509 antibody Background: ZNF509 May be involved in transcriptional regulation. It belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by... | |
| Mouse monoclonal ZNF544 antibody Background: ZNF544 may be involved in transcriptional regulation. | |
| Mouse monoclonal ZNF596 antibody Background: ZNF596 may be involved in transcriptional regulation. | |
| Mouse monoclonal ZNF76 antibody Background: ZNF76 may be involved in transcriptional regulation. | |
| Mouse monoclonal ZNF81 antibody Background: This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. | |
| Mouse monoclonal ZW10 antibody Background: The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN)... |
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