Mouse monoclonal KLF4 antibody
Background:
KLF4 is a transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. It binds to the promoter region of its own gene and can activate its own transcription. KLF4 also regulates the expression of key transcription factors during embryonic development, plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. It is also required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. KLF4 plays a role in the differentiation of epithelial cells and may also function in skeletal and kidney development. It also Contributes to the down-regulation of p53/TP53 transcription.
| Fitzgerald Industries International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | 10R-2810 |
| Product Name | KLF4 antibody |