Fitzgerald Industries International, Inc. NMNAT1 antibody 10R-1183

Description
Mouse monoclonal NMNAT1 antibody Background: Nicotinamide mononucleotide adenylyltransferase 1 is an enzyme that in humans is encoded by the NMNAT1 gene. It is an essential enzyme because it catalyzes the final step of NAD+ biosynthesis. There are three isoforms in humans that exhibit tissue- and organelle-specific expression. NMNAT-1 is localized exclusively in the nucleus, whereas NMNAT-2 and NMNAT-3 are found in the Golgi and mitochondria, respectively. NMNAT1 constitute a nuclear NAD+ salvage pathway which regulates the functions of NAD+-dependent enzymes such as the protein deacetylase SIRT1. NMNAT1 protects neurons from neuronal activity induced degeneration.
Description
Mouse monoclonal NMNAT1 antibody Background: Nicotinamide mononucleotide adenylyltransferase 1 is an enzyme that in humans is encoded by the NMNAT1 gene. It is an essential enzyme because it catalyzes the final step of NAD+ biosynthesis. There are three isoforms in humans that exhibit tissue- and organelle-specific expression. NMNAT-1 is localized exclusively in the nucleus, whereas NMNAT-2 and NMNAT-3 are found in the Golgi and mitochondria, respectively. NMNAT1 constitute a nuclear NAD+ salvage pathway which regulates the functions of NAD+-dependent enzymes such as the protein deacetylase SIRT1. NMNAT1 protects neurons from neuronal activity induced degeneration.

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Fitzgerald Industries International, Inc.
Acton, MA, USA
NMNAT1 antibody
10R-1183
NMNAT1 antibody 10R-1183
Mouse monoclonal NMNAT1 antibody Background: Nicotinamide mononucleotide adenylyltransferase 1 is an enzyme that in humans is encoded by the NMNAT1 gene. It is an essential enzyme because it catalyzes the final step of NAD+ biosynthesis. There are three isoforms in humans that exhibit tissue- and organelle-specific expression. NMNAT-1 is localized exclusively in the nucleus, whereas NMNAT-2 and NMNAT-3 are found in the Golgi and mitochondria, respectively. NMNAT1 constitute a nuclear NAD+ salvage pathway which regulates the functions of NAD+-dependent enzymes such as the protein deacetylase SIRT1. NMNAT1 protects neurons from neuronal activity induced degeneration.

Mouse monoclonal NMNAT1 antibody
Background:
Nicotinamide mononucleotide adenylyltransferase 1 is an enzyme that in humans is encoded by the NMNAT1 gene. It is an essential enzyme because it catalyzes the final step of NAD+ biosynthesis. There are three isoforms in humans that exhibit tissue- and organelle-specific expression. NMNAT-1 is localized exclusively in the nucleus, whereas NMNAT-2 and NMNAT-3 are found in the Golgi and mitochondria, respectively. NMNAT1 constitute a nuclear NAD+ salvage pathway which regulates the functions of NAD+-dependent enzymes such as the protein deacetylase SIRT1. NMNAT1 protects neurons from neuronal activity induced degeneration.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 10R-1183
Product Name NMNAT1 antibody
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