The Hamilton PRP-C18 bulk resin is a reversed-phase HPLC stationary phase designed for high-efficiency separations across a wide pH range and temperatures exceeding 100°C. It is mechanically and thermally stable, resistant to stripping or dissolution in strong acids or bases up to 1 M, and compatible with aggressive regeneration methods. Available in 12-20 µm particle size, it is intended for custom packing and applications requiring robust, long-lasting performance in clinical, pharmaceutical, and life science analyses. The resin does not swell or shrink and maintains performance in mobile phases from pH 1 to 13.
The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase has excellent mechanical and thermal stability (> 100°C), does not shrink or swell, and is completely inert to most conditions commonly encountered in reversed-phase chromatography.
The PRP-C18 is a durable and effective column for general purpose HPLC and especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries.
Oligonucleotide Purification
The properties of the PRP-C18 make it a superior column in the field of oligonucleotide purifications, providing:
Applications:
Organic compounds: small molecules (< 2,000 mw), pharmaceuticals, steroids, halides, vitamins, amino acid analysis, herbicides
Examples of analytes that can be separated on PRP-C18 columns:
| Hamilton Company | |
|---|---|
| Product Category | HPLC Columns |
| Product Number | 79793 |
| Product Name | PRP-C18, 12-20 µm, 100 Å, Bulk Resin (1 gram) |
| Stationary Phase/Separation Process | Reversed Phase |
