Sartorius Lab Instruments GmbH & Co. KG Sartopore® 2 XLG 0.2 µm Liquid Filter Cartridge 5442507G1

Sartopore® 2 XLG filter cartridges are especially designed for sterilizing grade filtration in special applications of cell culture processes. The unique heterogeneous double layer PES membrane combination of Sartopore® 2 XLG cartridges is specifically developed to deal with the broad variety of contaminants in up- and downstream processing of biotech applications. They provide consistently high total throughput performance for biological fluid streams independent from media and process variations. Applications: Typical applications of Sartopore® 2 XLG cartridges include sterilizing grade filtration of: – Plant peptone or yeast supplemented cell culture media – Serum containing cell culture media – Other cell culture media used in biotech manufacturing – Clarified cell culture harvest – Downstream Intermediates (before and after UF|DF and chromatography steps). Economy: The combination of the built-in 0.8 μm pre-filter in front of a 0.2 μm final filter together with an exceptionally high effective filtration area of 0.8 m²/10” cartridge provide outstanding total throughput and flow rate performance in the target applications. Thus ensuring highest process efficiency, minimized filtration costs and short filtration cycle times. Compatibility: The PES membrane of Sartopore® 2 XLG cartridges provides broad chemical compatibility from pH 1 to pH 14 and low extractable levels. They are compatible with multiple in-line steam sterilization cycles up to 134°C. Scalability: Sartopore® 2 XLG filter elements are available in a broad range of sizes and formats to provide linear scale-up from R&D to process scale. Microbiological Retention: Sartopore® 2 XLG filter cartridges are fully validated as sterilizing grade filters according to HIMA and ASTM F-838-05 guidelines. Quality Control: Each individual element is tested for integrity by B.-P. and Diffusion-Test prior to be released assuring absolute reliability. Documentation: Sartopore® 2 XLG cartridges are designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System. A Validation Guide is available for compliance with regulatory requirements. Applications: Typical applications of Sartopore® 2 XLG cartridges include sterilizing grade filtration of: Plant peptone or yeast supplemented cell culture media Serum containing cell culture media Other cell culture media used in biotech manufacturing Clarified cell culture harvest Downstream Intermediates (before and after UF|DF and chromatography steps) Economy: The combination of the build in 0.8 µm pre-filter in front of a 0.2 µm final filte together with an exceptionally high effective filtration area of 0.8 m²/10” cartridge provide outstanding total throughput and flow rate performance in the target applications. Thus ensuring highest process efficiency, minimized filtration costs and short filtration cycle times. Compatibility: The PES membrane of Sartopore® 2 XLG cartridges provides broad chemical compatibility from pH 1 to pH 14 and low extractable levels. They are compatible with multiple in-line steam sterilization cycles up to 134°C. Scalability: Sartopore® 2 XLG filter elements are available in a broad range of sizes and formats to provide linear scale-up from R&D to process scale. Microbiological Retention: Sartopore® 2 XLG filter cartridges are fully validated as sterilizing grade filters according to HIMA and ASTM F-838-05 guidelines. Quality Control: Each individual element is tested for integrity by B.-P. and Diffusion-Test prior to be released assuring absolute reliability. Documentation: Sartopore® 2 XLG cartridges are designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System. A Validation Guide is available for compliance with regulatory requirements.