Sartorius Lab Instruments GmbH & Co. KG Sartopore® 2 XLG 0.2 µm Liquid Filter Cartridge 5441307G4--**--B

Sartopore® 2 XLG Capsule Size 4 is a self contained filter unit which is especially developed for sterilizing grade filtration in special applications of cell culture processes. It is designed for use in small scale production of high valuable pharmaceutical and biotech products. Featuring the same materials and type of construction as any other Sartopore® 2 XLG filter element, Sartopore® 2 XLG Capsule Size 4 is ideally suited for R&D Labs in pharmaceutical development. The unique heterogeneous double layer PES membrane combination of Sartopore® 2 XLG Capsule Size 4 is specifically developed to deal with the broad variety of contaminants in up- and downstream processing of biotech applications. They provide consistently high total throughput performance for biological fluid streams independent from media and process variations. Applications: Typical applications of Sartopore® 2 XLG Capsules Size 4 include sterilizing grade filtration of: – Plant peptone or yeast supplemented cell culture media – Serum containing cell culture media – Other cell culture media used in biotech manufacturing – Clarified cell culture harvest – Downstream Intermediates (before and after UF|DF and chromatography steps). Economy: The combination of the built-in 0.8 µm pre-filter in front of a 0.2 µm final filter together with the 30% enlarged effective filtration area per XLG filter element provide an outstanding total throughput and flow rate performance in the target applications. Thus ensuring highest process efficiency, minimized filtration costs and short filtration cycle times. Compatibility: The PES membrane of Sartopore® 2 XLG Capsules Size 4 provides broad chemical compatibility from pH 1 to pH 14 and low extractable levels. They are compatible with multiple autoclaving cycles up to 134°C. Scalability: Sartopore® 2 XLG filter elements are available in a broad range of sizes and formats to provide linear scale-up from R&D to process scale. Microbiological Retention: Sartopore® 2 XLG Capsules Size 4 are fully validated as sterilizing grade filters according to HIMA and ASTM F-838-05 guidelines. Quality Control: Each individual element is tested for integrity by B.-P. and Diffusion-Test prior to be released assuring absolute reliability. Documentation: Sartopore® 2 XLG Capsules Size 4 are designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System. A Validation Guide is available for compliance with regulatory requirements. Applications: Typical applications of Sartopore® 2 XLG Capsules Size 4 include sterilizing grade filtration of: – Plant peptone or yeast supplemented cell culture media – Serum containing cell culture media – Other cell culture media used in biotech manufacturing – Clarified cell culture harvest – Downstream Intermediates (before and after UF|DF and chromatography steps). Typical applications of Sartopore® 2 XLG Capsules Size 4 include sterilizing grade filtration of: Plant peptone or yeast supplemented cell culture media Serum containing cell culture media Other cell culture media used in biotech manufacturing Clarified cell culture harvest Downstream Intermediates (before and after UF|DF and chromatography steps) Economy: The combination of the built-in 0.8 µm pre-filter in front of a 0.2 µm final filter together with the 30% enlarged effective filtration area per XLG filter element provide an outstanding total throughput and flow rate performance in the target applications. Thus ensuring highest process efficiency, minimized filtration costs and short filtration cycle times. Compatibility: The PES membrane of Sartopore® 2 XLG MidiCaps provides broad chemical compatibility from pH 1 to pH 14 and low extractable levels. They are compatible with multiple in line steam sterilization cycles up to 134°C. Scalability: Featuring the same materials and type of construction as any other Sartopore® 2 XLG filter element, Sartopore® P 2 XLG Capsules Size 4 are ideally suited for R&D Labs in pharmaceutical development. Filtration trials can be performed using extremely small volumes of high value products. Microbiological Retention: Sartopore® 2 XLG Capsules Size 4 are fully validated as sterilizing grade filters according to HIMA and ASTM F-838-05 guidelines. Quality Control: Each individual element is tested for integrity by B.-P. and Diffusion-Test prior to be released assuring absolute reliability. Documentation: Sartopore® 2 XLG Capsules Size 4 are designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System. A Validation Guide is available for compliance with regulatory requirements.