Sartorius Lab Instruments GmbH & Co. KG Sartobran® P MidiCaps® 0.45 µm Liquid Filter Capsules 5235306D8--**--A

MidiCaps is the innovative all new disposable capsule plattform technology from Sartorius. MidiCaps focus on design improvements of the capsule housing to permit the use of filter capsules in aseptic processing. MidiCaps are available for all existing filter media from Sartorius. Sartobran P membrane filter MidiCaps 0.45 μm rated are ideally suited for bioburden and defined particle reduction from bio-pharmaceutical solutions. They can be used for protection of sterilizing grade membrane filters or subsequent downstream processing equipment in biotech production processes.The unique low unspecific binding capacity of the cellulose acetate membranes assures highest protein yield and rapid preservative recovery. Sartobran P filters are ideally suited for prefiltration of high value biological solutions and pharmaceuticals sensitive to adsorption as well as for final filtration of LVP´s and Buffers. Due to the "built-in prefiltration" by a 0.65 µm membrane, Sartobran P 0.45 µm filters provide excellent total throughputs and higher flow rates at low differential pressure for gentle product treatment. MaxiCaps are designed, developed and manufactured in accordance with a ISO 9001 certified Quality Management System. Each individual element is tested for integrity by Diffusion- and Bubble-Point-Test prior to be released assuring absolute reliability and a Validation Guide is available for compliance with regulatory requirements. Applications: Featuring extremely low adsorptive cellulose acetate membranes, Sartobran P filter elements are ideally suited for filtration of highly valuable protein solutions or solutions containing preservatives. They assure highest protein yield and rapid preservative recovery. Typical applications include: Coagulation Factors, Albumin, IgG Bacterial and Viral Vaccines MAB Bio-processed Pharmaceuticals Diagnostics Purified Protein Solutions Biological Fluids Fluids containing preservatives Easy to Use: Sartobran P MidiCaps are delivered as individually packed sterile units. On site, pre-use sterilization can be eliminated. Flexibility: Sartobran P 0.45 μm MidiCaps are available with various filtration areas from 500 cm² | 0.5 ft² up to 0.45 m² | 5 ft² for easy adoption to any filtration process independent from the batch size. Scalability: Consistent and predictable scale-up and down trials can reliably be performed as all Sartobran P filter elements are produced with the same type of membrane and identical materials of construction. Cost Saving: The use of the disposable capsule design concept avoids investments into stainless steel filter housings and eliminates additional costs for cleaning of housings and cleaning validation. Quality Control: Each individual element is tested for integrity by B.-P. and Diffusion-Test prior to be released assuring absolute reliability. Documentation: Sartobran P 0.45 μm Capsules are delivered as individually packed sterile units. On site, pre-use sterilization can be eliminated.