Fitzgerald Industries International, Inc. Datasheets for Biological Materials

Biological materials are biocompatible materials, natural or man-made, that comprise a whole or a part of a living structure or biomedical device that performs, augments, or replaces a natural function
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Product Name Notes
Rabbit polyclonal ABCF2 antibody Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and...
Rabbit polyclonal AChE antibody Yt blood group Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on...
Rabbit polyclonal ACOT11 antibody raised against the middle region of ACOT11 Background: ACOT11 is a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Expression...
Rabbit polyclonal ACPP antibody raised against the middle region of ACPP Background: This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is...
Rabbit polyclonal ADA antibody raised against the middle region of ADA Background: ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for...
Rabbit polyclonal ADA antibody raised against the N terminal of ADA Background: ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for...
Rabbit polyclonal ADAM12 antibody Background: ADAM12 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom...
Rabbit polyclonal ADAM15 antibody raised against the middle region of ADAM15 Background: ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type...
Rabbit polyclonal ADAM2 antibody Background: ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom...
Rabbit polyclonal ADAM33 antibody raised against the middle region of ADAM33 Background: ADAM33 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are...
Rabbit polyclonal ADAM9 antibody Background: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom...
Rabbit polyclonal ADAMDEC1 antibody raised against the middle region of ADAMDEC1 Background: This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression...
Rabbit polyclonal ADAR antibody raised against the C terminal of ADAR Background: ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through...
Rabbit polyclonal ADAR antibody raised against the N terminal of ADAR Background: ADAR is responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through...
Rabbit polyclonal ADCY6 antibody raised against the C terminal of ADCY6 Background: ADCY6 is adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger...
Rabbit polyclonal ADCY8 antibody Background: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several...
Rabbit polyclonal ADRB1 antibody raised against the middle region of ADRB1 Background: The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of...
Rabbit polyclonal AGER antibody raised against the C terminal of AGER Background: AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular...
Rabbit polyclonal AGT antibody Background: AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting...
Rabbit polyclonal AGTR1 antibody raised against the N terminal of AGTR1 Background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important...
Rabbit polyclonal AHSG antibody raised against the N terminal of AHSG Background: Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of...
Rabbit polyclonal AK3 antibody raised against the N terminal of AK3 Background: The AK3 protein is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding...
Rabbit polyclonal ALOX15 antibody raised against the middle region of ALOX15 Background: ALOX15 converts arachidonic acid to 15S-hydroperoxyeicos atetraenoic acid. ALOX15 also acts on C-12 of arachidonate as well as...
Rabbit polyclonal AMH antibody raised against the middle region of AMH Background: Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian...
Rabbit polyclonal Annexin A10 antibody raised against the middle region of ANXA10 Background: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play...
Rabbit polyclonal Annexin A4 antibody raised against the middle region of ANXA4 Background: Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are...
Rabbit polyclonal Annexin A8-Like 2 antibody raised against the middle region of ANXA8L2 Background: ANXA8L2 is a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins.
Rabbit polyclonal Annexin A8-Like 2 antibody raised against the N terminal of ANXA8L2 Background: ANXA8L2 is a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins.
Rabbit polyclonal ANP32A antibody Background: ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may...
Rabbit polyclonal ApoBEC3G antibody raised against the N terminal of APOBEC3G Background: APOBEC3G is a member of the cytidine deaminase gene family. It is one of seven related genes or...
Rabbit polyclonal APP antibody raised against the middle region of APP Background: APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a...
Rabbit polyclonal ARAF antibody raised against the middle region of ARAF Background: ARAF belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily. It contains 1 phorbol-ester/DAG-ty...
Rabbit polyclonal ARF1 antibody raised against the middle region of ARF1 Background: ADP-ribosylation factor 1 (ARF1) is a member of the human ARF family. The family is composed of small...
Rabbit polyclonal ARF6 antibody raised against the middle region of ARF6 Background: ARF6 is a member of the human ARF family, which is part of the RAS superfamily. They are...
Rabbit polyclonal ARHGDIG antibody Background: ARHGDIG is highly expressed in the entire brain, with regional variations. The mRNA is also present at high levels in kidney and pancreas and at...
Rabbit polyclonal ARL5A antibody raised against the middle region of ARL5A Background: The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. With its distinctive nuclear/nucleolar...
Rabbit polyclonal ARL6IP2 antibody raised against the C terminal of ARL6IP2 Background: ARL6IP2 is a multi-pass membrane proteinPotential. It belongs to the GBP family. Atlastin GTPases are required for Golgi...
Rabbit polyclonal ARL8A antibody raised against the middle region of ARL8A Background: ARL8A belongs to the small GTPase superfamily, Arf family. ARL8A m,ay play a role in lysosomes motility. Alternatively,...
Rabbit polyclonal ARMC3 antibody raised against the middle region of ARMC3 Background: Armadillo/beta-caten in like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such...
Rabbit polyclonal ASB12 antibody raised against the C terminal of ASB12 Background: ASB12 is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin...
Rabbit polyclonal ASB5 antibody raised against the C terminal of ASB5 Background: They contain ankyrin repeat sequence and SOCS box domain. The SOCSbox serves to couple suppressor of cytokine signalling...
Rabbit polyclonal ASB6 antibody raised against the middle region of ASB6 Background: ASB6 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a...
Rabbit polyclonal ASB8 antibody raised against the N terminal of ASB8 Background: ASB8 may be a substrate-recognitio n component of a SCF-like ECS (Elongin-Cullin-SOCS -box protein) E3 ubiquitin-protein ligase complex...
Rabbit polyclonal Astrotactin 2 antibody raised against the N terminal of ASTN2 Background: ASTN2 may play an important role in neuronal functioning.
Rabbit polyclonal ATG5 antibody Background: ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from...
Rabbit polyclonal ATL3 antibody raised against the middle region of Dkfzp564J0863 Background: DKFZP564J0863(ATL3, atlastin GTPase 3) belongs to the GBP family.In the family of human GTPases, atlastin-2 and -3 are...
Rabbit polyclonal ATL3 antibody raised against the middle region of Dkfzp564J0863 Background: The function of DKFZP564J0863 protein has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal ATP2A2 antibody raised against the C terminal of ATP2A2 Background: ATP2A2 is one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula...
Rabbit polyclonal ATP2C1 antibody raised against the C terminal of ATP2C1 Background: ATP2C1 belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP...
Rabbit polyclonal ATP6V0A2 antibody raised against the N terminal of ATP6V0A2 Background: The multisubunit vacuolar-type proton pump (H(+)-ATPase or V-ATPase) is essential for acidification of diverse cellular components, including endosomes,...
Rabbit polyclonal AZGP1 antibody raised against the N terminal of AZGP1 Background: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. AZGP1 may...
Rabbit polyclonal BAG3 antibody raised against the middle region of BAG3 Background: BAG3 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. BAG3 has anti-apoptotic activity.
Rabbit polyclonal BCAP31 antibody raised against the middle region of BCAP31 Background: BCAP31 is a member of the B-cell receptor associated protein 31 superfamily. It is a multi-pass transmembrane protein...
Rabbit polyclonal BDNF antibody raised against the middle region of BDNF Background: BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is...
Rabbit polyclonal BECN1 antibody raised against the N terminal of BECN1 Background: BECN1 plays a central role in autophagy. BECN1 may play a role in antiviral host defense. BECN1 protects...
Rabbit polyclonal Beta 2 Microglobulin antibody raised against the N terminal of B2M Background: This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class...
Rabbit polyclonal Beta Tubulin antibody raised against the N terminal of TUBB Background: TUBB belongs to the tubulin family. Tubulin is the major constituent of microtubules. It binds two moles...
Rabbit polyclonal BLNK antibody raised against the middle region of BLNK Background: This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.
Rabbit polyclonal BMP6 antibody raised against the middle region of BMP6 Background: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth.
Rabbit polyclonal C1ORF166 antibody raised against the middle region of C1Orf166 Background: C1orf166 encodes an ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation...
Rabbit polyclonal C1QB antibody raised against the C terminal of C1QB Background: C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in...
Rabbit polyclonal C1QB antibody raised against the middle region of C1QB Background: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement...
Rabbit polyclonal C20ORF10 antibody raised against the middle region of C20Orf10 Background: C20orf10 may play a significant role in p53/TP53-mediating signaling pathway.
Rabbit polyclonal C20ORF10 antibody raised against the N terminal Of C20Orf10 Background: C20orf10 may play a significant role in p53/TP53-mediating signaling pathway.
Rabbit polyclonal C4BPA antibody raised against the middle region of C4BPA Background: C4BPA is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of...
Rabbit polyclonal C4BPB antibody raised against the N terminal of C4BPB Background: C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of...
Rabbit polyclonal Calcitonin Receptor-Like antibody raised against the N terminal of CALCRL Background: CALCRL is the receptor for calcitonin-gene-rela ted peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together...
Rabbit polyclonal CAMKII antibody raised against the N terminal of CAMKK2 Background: CAMKK2 is a calcium/calmodulin-d ependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number...
Rabbit polyclonal CANT1 antibody raised against the middle region of CANT1 Background: CANT1 belongs to the apyrase family.It is a calcium-dependent nucleotidase with a preference for UDP. The order of...
Rabbit polyclonal CANT1 antibody raised against the middle region of CANT1 Background: This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with...
Rabbit polyclonal CAP1 antibody Background: The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein...
Rabbit polyclonal CAPS antibody raised against the N terminal of CAPS Background: CAPS is a calcium-binding protein, which may play a role in the regulation of ion transport. A similar...
Rabbit polyclonal CCK antibody raised against the middle region of CCK Background: Cholecystokinin (CCK) is a brain/gut peptide. In the gut, it induces the release of pancreatic enzymes and the...
Rabbit polyclonal CCR2 antibody Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in...
Rabbit polyclonal CCRL2 antibody Background: CCRL2 is a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their...
Rabbit polyclonal CD160 antibody raised against the middle region of CD160 Background: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is...
Rabbit polyclonal CD36 antibody Background: CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins...
Rabbit polyclonal CD40 antibody raised against the N terminal of CD40 Background: CD40 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating...
Rabbit polyclonal CD40 antibody raised against the N terminal of CD40 Background: CD40 is the receptor for TNFSF5/CD40LG. Defects in CD40 are the cause of hyper-IgM immunodeficiency type 3 (HIGM3).
Rabbit polyclonal CD40L antibody Background: CD40LG is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in...
Rabbit polyclonal CD5 antibody raised against the N terminal of CD5 Background: CD5 may act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2.
Rabbit polyclonal CD8B antibody raised against the middle region of CD8B Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell...
Rabbit polyclonal CD8B antibody raised against the N terminal of CD8B Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell...
Rabbit polyclonal CDH1 antibody Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting...
Rabbit polyclonal CDH12 antibody Background: CDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane...
Rabbit polyclonal CDH16 antibody raised against the N terminal of CDH16 Background: CDH16 is a member of the cadherin superfamily, which are calcium-dependent, membrane-associated glycoproteins. CDH16 consists of an extracellular...
Rabbit polyclonal CDH23 antibody raised against the middle region of CDH23 Background: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The...
Rabbit polyclonal CDH24 antibody raised against the N terminal of CDH24 Background: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting...
Rabbit polyclonal CDH4 antibody Background: CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a...
Rabbit polyclonal CDH7 antibody raised against the N terminal of CDH7 Background: CDH7 is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and...
Rabbit polyclonal CDH8 antibody raised against the middle region of CDH8 Background: CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell...
Rabbit polyclonal CECR1 antibody raised against the N terminal of CECR1 Background: CECR1 a member of a subfamily of the adenosine deaminase protein family. It may act as a growth...
Rabbit polyclonal CFP antibody raised against the middle region of CFP Background: CFP is a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system.
Rabbit polyclonal CFP antibody raised against the N terminal of CFP Background: CFP is a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system.
Rabbit polyclonal CHGN antibody raised against the C terminal Of Chgn Background: ChGn transfers 1,4-N-acetylgalactos amine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). This protein is...
Rabbit polyclonal CHIA antibody raised against the middle region of CHIA Background: CHIA belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. It contains 1 chitin-binding type-2 domain.
Rabbit polyclonal CHIA antibody raised against the N terminal of CHIA Background: CHIA belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. It contains 1 chitin-binding type-2 domain.
Rabbit polyclonal CHN1 antibody Background: CHN1 contains 1 phorbol-ester/DAG-ty pe zinc finger, 1 Rho-GAP domain and 1 SH2 domain. CHN1 is a GTPase-activating protein for p21-rac and a phorbol ester...
Rabbit polyclonal Claudin 1 antibody raised against the C terminal of CLDN1 Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals...
Rabbit polyclonal Claudin 11 antibody Background: CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary...
Rabbit polyclonal Claudin 15 antibody raised against the middle region of CLDN15 Background: CLDN15 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Rabbit polyclonal Claudin 16 antibody raised against the C terminal of CLDN16 Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals...
Rabbit polyclonal Claudin 18 antibody raised against the middle region of CLDN18 Background: CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Rabbit polyclonal Claudin 19 antibody raised against the C terminal of CLDN19 Background: CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the...
Rabbit polyclonal Claudin 23 antibody raised against the C terminal of CLDN23 Background: CLDN23 is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C- X(8-10)-C. It is a candidate tumor...
Rabbit polyclonal Claudin 5 antibody Background: CLDN5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as...
Rabbit polyclonal Claudin 7 antibody raised against the middle region of CLDN7 Background: Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions...
Rabbit polyclonal CLEC4M antibody raised against the middle region of CLEC4M Background: CLEC4M is a transmembrane receptor and is often referred to as L-SIGN because of its expression in the...
Rabbit polyclonal CLEC4M antibody raised against the n terminal of CLEC4M Background: CLEC4M is a transmembrane receptor and is often referred to as L-SIGN because of its expression in the...
Rabbit polyclonal CNTNAP1 antibody raised against the N terminal of CNTNAP1 Background: CNTNAP1 was initially identified as a 190 kDa protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein,...
Rabbit polyclonal CNTNAP3 antibody raised against the middle region of CNTNAP3 Background: The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a...
Rabbit polyclonal CNTNAP4 antibody raised against the N terminal of CNTNAP4 Background: CNTNAP4 belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion...
Rabbit polyclonal COLEC12 antibody raised against the middle region of COLEC12 Background: COLEC12 is a member of the C-lectin family,proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein...
Rabbit polyclonal COLEC12 antibody raised against the N terminal of COLEC12 Background: COLEC12 is a member of the C-lectin family,proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein...
Rabbit polyclonal Collagen Type IV alpha 3 antibody Background: This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of...
Rabbit polyclonal Collagen Type VI Alpha 1 antibody raised against the middle region of COL6A1 Background: The collagens are a superfamily of proteins that play a role in maintaining the...
Rabbit polyclonal Collagen Type XI Alpha 2 antibody raised against the N terminal of COL11A2 Background: This gene encodes one of the two alpha chains of type XI collagen, a...
Rabbit polyclonal Complement C2 antibody raised against the N terminal of C2 Background: Component C2 is part of the classical pathway of complement system. Activated C1 cleaves C2 into C2a...
Rabbit polyclonal Complement C4b antibody Background: C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor...
Rabbit polyclonal Complement C8b antibody raised against the middle region of C8B Background: C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement...
Rabbit polyclonal COPA antibody raised against the middle region of COPA Background: In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated...
Rabbit polyclonal COPA antibody raised against the N terminal of COPA Background: In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated...
Rabbit polyclonal CRLF1 antibody raised against the middle region of CRLF1 Background: CRLF1 belongs to the type I cytokine receptor family. It is cytokine receptor subunit, possibly playing a regulatory...
Rabbit polyclonal CSF1 antibody Background: CSF1 is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked...
Rabbit polyclonal CSGALNACT1 antibody raised against the N terminal Of Csgalnact1 Background: CSGALNACT1 is a transfers 1,4-N-acetylgalactos amine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). It...
Rabbit polyclonal CSHL1 antibody raised against the C terminal of CSHL1 Background: CSHL1 is a member of the somatotropin/prolact in family of hormones which play an important role in growth...
Rabbit polyclonal CSPG5 antibody Background: CSPG5 may function as a growth and differentiation factor involved in neuritogenesis. It may induce ERBB3 activation.
Rabbit polyclonal CXCL16 antibody Background: CXCL16 acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology...
Rabbit polyclonal CYBB antibody Background: CYBB is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers...
Rabbit polyclonal DAPK1 antibody raised against the N terminal of DAPK1 Background: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally...
Rabbit polyclonal DCBLD1 antibody raised against the N terminal of DCBLD1 Background: The function of DCBLD1 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal DCX antibody Background: In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which...
Rabbit polyclonal DDAH1 antibody raised against the middle region of DDAH1 Background: DDAH1 belongs to the dimethylarginine dimethylaminohydrola se (DDAH) family. This enzyme plays a role in nitric oxide generation...
Rabbit polyclonal DDAH2 antibody raised against the N terminal of DDAH2 Background: DDAH2 hydrolyzes N(G),N(G)-dimethyl-L -arginine (ADMA) and N(G)-monomethyl-L-ar ginine (MMA) which act as inhibitors of NOS. DDAH2 has therefore...
Rabbit polyclonal Desmocollin 3 antibody raised against the N terminal of DSC3 Background: DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily.
Rabbit polyclonal Desmoglein 2 antibody raised against the N terminal of DSG2 Background: Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. DSG2 is a calcium-binding transmembrane...
Rabbit polyclonal DFFB antibody Background: DFFB is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. DFFB degrades naked DNA and induces apoptotic morphology.
Rabbit polyclonal DGCR2 antibody raised against the middle region of DGCR2 Background: Deletions of the 22q11.2 have been associated with a wide range of developmental defects classified under the acronym...
Rabbit polyclonal DGCR2 antibody raised against the N terminal of DGCR2 Background: DGCR2 is the putative adhesion receptor that could be involved in cell-cell or cell-matrix interactions required for normal...
Rabbit polyclonal DGKA antibody raised against the N terminal of DGKA Background: The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator...
Rabbit polyclonal DGKE antibody raised against the N terminal of DGKE Background: Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the...
Rabbit polyclonal DGKH antibody raised against the middle region of DGKH Background: DGKH is a member of the diacylglycerol kinase (DGK) enzyme family of proteins, specifically the type II DGK...
Rabbit polyclonal DIRAS1 antibody raised against the middle region of DIRAS1 Background: DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases.
Rabbit polyclonal DIRAS1 antibody raised against the N terminal of DIRAS1 Background: DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases.
Rabbit polyclonal DLL1 antibody Background: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell...
Rabbit polyclonal DOCK2 antibody raised against the middle region of DOCK2 Background: The DOCK2 gene encodes a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis.
Rabbit polyclonal DSCAM antibody raised against the middle region of DSCAM Background: DSCAM is a cell adhesion molecule that can mediate cation-independent homophilic binding activity. DSCAM could be involved in...
Rabbit polyclonal DUSP10 antibody raised against the N terminal of DUSP10 Background: Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threon ine and phosphotyrosine residues.
Rabbit polyclonal DUSP8 antibody raised against the middle region of DUSP8 Background: DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by...
Rabbit polyclonal DVL2 antibody Background: DVL2 is a member of the dishevelled (dsh) protein family. It is a 90 kDa protein that undergoes posttranslational phosphorylation to form a 95 kDa...
Rabbit polyclonal ECT2 antibody raised against the middle region of ECT2 Background: ECT2 is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The...
Rabbit polyclonal Ectodysplasin A antibody raised against the middle region of EDA Background: EDA is a type II membrane protein that can be cleaved by furin to produce a secreted...
Rabbit polyclonal ELMO3 antibody raised against the middle region of ELMO3 Background: ELMO3 is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell...
Rabbit polyclonal ELMOD2 antibody raised against the N terminal of ELMOD2 Background: ELMOD2 is an engulfment and motility (ELMO) domain-containing protein.
Rabbit polyclonal Ephrin-B1 antibody raised against the middle region of EFNB1 Background: The protein encoded by this gene is a type I membrane protein and a ligand of Eph-related receptor...
Rabbit polyclonal EPOr antibody raised against the N terminal of EPOR Background: The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates...
Rabbit polyclonal ERAS antibody raised against the middle region of ERAS Background: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. ERAS plays an important role in the tumor-like growth...
Rabbit polyclonal EXT1 antibody Background: EXT1 is an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. This gene encodes an endoplasmic reticulum-resident...
Rabbit polyclonal EXT2 antibody Background: EXT2 is one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis.
Rabbit polyclonal FCER1A antibody raised against the middle region of FCER1A Background: The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the...
Rabbit polyclonal FCGRT antibody raised against the N terminal of FCGRT Background: FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk.
Rabbit polyclonal FEM1B antibody Background: FEM1B is a component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. It involved in apoptosis by...
Rabbit polyclonal FES antibody raised against the N terminal of FES Background: FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific...
Rabbit polyclonal FGF13 antibody raised against the middle region of FGF13 Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family...
Rabbit polyclonal FGF21 antibody raised against the N terminal of FGF21 Background: FGF21 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and...
Rabbit polyclonal Fibronectin 1 antibody raised against the N terminal of FN1 Background: FN1 is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or...
Rabbit polyclonal FICD antibody raised against the C terminal of FICD Background: FICD is an adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
Rabbit polyclonal FKBP8 antibody raised against the C terminal of FKBP8 Background: FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular...
Rabbit polyclonal FKBP8 antibody raised against the N terminal of FKBP8 Background: FKBP8 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular...
Rabbit polyclonal FTH1 antibody raised against the middle region of FTH1 Background: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It...
Rabbit polyclonal FXYD5 antibody raised against the middle region of FXYD5 Background: FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence...
Rabbit polyclonal FYN antibody raised against the middle region of FYN Background: FYN is a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein...
Rabbit polyclonal FYN antibody raised against the N terminal of FYN Background: FYN is a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein...
Rabbit polyclonal G3BP1 antibody Background: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an...
Rabbit polyclonal GADD45B antibody raised against the middle region of GADD45B Background: GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest...
Rabbit polyclonal GALNAC4S-6ST antibody raised against the middle region of GALNAC4S-6ST Background: GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the...
Rabbit polyclonal GBP2 antibody raised against the N terminal of GBP2 Background: GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). GBP2 is a...
Rabbit polyclonal GDF15 antibody raised against the N terminal of GDF15 Background: Bone morphogenetic proteins are members of the transforming growth factor-beta superfamily and regulate tissue differentiation and maintenance.
Rabbit polyclonal GDF2 antibody raised against the middle region of GDF2 Background: GDF2 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of...
Rabbit polyclonal GEM antibody raised against the N terminal of GEM Background: GEM belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the...
Rabbit polyclonal GHRHR antibody raised against the N terminal of GHRHR Background: GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis...
Rabbit polyclonal GJA1 antibody raised against the middle region of GJA1 Background: Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap...
Rabbit polyclonal GJA1 antibody raised against the N terminal of GJA1 Background: Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap...
Rabbit polyclonal GJA3 antibody raised against the N terminal of GJA3 Background: GJA3 belongs to the connexin family. One gap junction consists of a cluster of closely packed pairs of...
Rabbit polyclonal GJA4 antibody raised against the middle region of GJA4 Background: GJA4 is a member of the connexin family. The protein is a component of gap junctions, which are...
Rabbit polyclonal GJA5 antibody raised against the N terminal of GJA5 Background: GJA5 belongs to the connexin family, alpha-type subfamily. It is an integral membrane protein that forms transmembrane channels,...
Rabbit polyclonal GJA8 antibody raised against the middle region of GJA8 Background: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which...
Rabbit polyclonal GJA9 antibody raised against the middle region of GJA9 Background: Connexins, such as GJA9, are involved in the formation of gap junctions, intercellular conduits that directly connect the...
Rabbit polyclonal GJB1 antibody raised against the middle region of GJB1 Background: This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins...
Rabbit polyclonal GJB6 antibody raised against the middle region of GJB6 Background: Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed...
Rabbit polyclonal GJC1 antibody raised against the middle region of GJC1 Background: GJC1 is a member of the connexin family. The protein is a component of gap junctions, which are...
Rabbit polyclonal GJC2 antibody raised against the middle region of GJC2 Background: GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins...
Rabbit polyclonal GJD2 antibody raised against the middle region of GJD2 Background: GJD2 is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate...
Rabbit polyclonal GJD4 antibody raised against the middle region of GJD4 Background: Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the...
Rabbit polyclonal GLMN antibody raised against the middle region of GLMN Background: GLMN is a phosphorylated protein that is a member of a Skp1-Cullin-F-box-li ke complex. The protein is essential...
Rabbit polyclonal GLMN antibody raised against the N terminal of GLMN Background: GLMN is a phosphorylated protein that is a member of a Skp1-Cullin-F-box-li ke complex. The protein is essential...
Rabbit polyclonal GLP2R antibody raised against the N terminal of GLP2R Background: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans...
Rabbit polyclonal Glucagon antibody raised against the middle region of GCG Background: GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is...
Rabbit polyclonal Glycoprotein Ib antibody Background: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked...
Rabbit polyclonal GMF gamma antibody raised against the middle region of GMFG Background: The function of GMF gamma protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal GNA15 antibody raised against the N terminal of GNA15 Background: GNA15 belongs to the G-alpha family. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in...
Rabbit polyclonal GNAI2 antibody Background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of...
Rabbit polyclonal GNAQ antibody Background: Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways.
Rabbit polyclonal GNB2L1 antibody Background: GNB2L1 seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. GNB2L1 may be involved in...
Rabbit polyclonal GNB2L1 antibody Background: GNB2L1 seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton.
Rabbit polyclonal GPR177 antibody raised against the middle region of GPR177 Background: GPR177 has signal transducer activity. It is positive regulation of I-kappaB kinase/NF-kappaB cascade.
Rabbit polyclonal Granzyme A antibody Background: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognise, bind, and lyse specific target cells. They are thought...
Rabbit polyclonal GRK5 antibody raised against the middle region of GRK5 Background: GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein...
Rabbit polyclonal Growth Hormone 2 antibody raised against the middle region of GH2 Background: GH2 is a member of the somatotropin/prolact in family of hormones which play an important role...
Rabbit polyclonal GUCY1B3 antibody raised against the N terminal of GUCY1B3 Background: Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3,...
Rabbit polyclonal HABP2 antibody raised against the middle region of HABP2 Background: HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. It is...
Rabbit polyclonal HAMP antibody raised against the N terminal of HAMP Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary...
Rabbit polyclonal HAPLN1 antibody raised against the N terminal of HAPLN1 Background: HAPLN1 stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
Rabbit polyclonal Heme Oxygenase antibody Background: HMOX1 belongs to the heme oxygenase family. Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted...
Rabbit polyclonal HFE antibody raised against the C terminal of HFE Background: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M).
Rabbit polyclonal HFE antibody raised against the N terminal of HFE Background: HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M).
Rabbit polyclonal HGF antibody Background: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte...
Rabbit polyclonal HLA-DPA1 antibody raised against the middle region of HLA-DPA1 Background: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting...
Rabbit polyclonal ICAM5 antibody raised against the N terminal of ICAM5 Background: ICAM5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane...
Rabbit polyclonal IFIT2 antibody raised against the N terminal of IFIT2 Background: IFIT2 belongs to the IFIT family. It contains 6 TPR repeats. IFIT2 inhibits migration activity and increases survival...
Rabbit polyclonal IFIT5 antibody raised against the middle region of IFIT5 Background: IFIT5 belongs to the IFIT family. It contains 8 TPR repeats. The exact function of IFIT5 remains unknown.
Rabbit polyclonal IFIT5 antibody raised against the N terminal of IFIT5 Background: IFIT5 belongs to the IFIT family. It contains 8 TPR repeats. The exact function of IFIT5 remains unknown.
Rabbit polyclonal IFT140 antibody Background: IFT140 contains 9 TPR repeats and 5 WD repeats. The function of the IFT140 protein remains unknown.
Rabbit polyclonal IGFALS antibody raised against the middle region of IGFALS Background: IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production...
Rabbit polyclonal IGFALS antibody raised against the middle region of IGFALS Background: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life...
Rabbit polyclonal IGSF1 antibody raised against the middle region of IGSF1 Background: Members of the immunoglobulin (Ig) superfamily, which includes IGSF1, have a variety of functions, but all appear to...
Rabbit polyclonal IGSF1 antibody raised against the N terminal of IGSF1 Background: Members of the immunoglobulin (Ig) superfamily, which includes IGSF1, have a variety of functions, but all appear to...
Rabbit polyclonal IL15 antibody raised against the N terminal of IL15 Background: IL15 is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine...
Rabbit polyclonal IL22 antibody raised against the C terminal of IL22 Background: IL22 belongs to the IL-10 family. It is a cytokine that contributes to the inflammatory response in vivo.
Rabbit polyclonal IL4 antibody raised against the middle region of IL4 Background: IL4 is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4...
Rabbit polyclonal IL5 antibody Background: IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of...
Rabbit polyclonal IL8RB antibody raised against the N terminal of IL8RB Background: IL8RB is the receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the...
Rabbit polyclonal IL9 antibody raised against the middle region of IL9 Background: IL9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates...
Rabbit polyclonal INADL antibody Background: INADL is a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the...
Rabbit polyclonal Integrin Beta 8 antibody raised against the C terminal of ITGB8 Background: ITGB8 is a member of the integrin beta chain family and is a single-pass type I...
Rabbit polyclonal ITFG1 antibody raised against the N terminal of ITFG1 Background: ITFG1 belongs to the TIP family. It contains 1 FG-GAP repeat. ITFG1 is a modulator of T-cell function.
Rabbit polyclonal ITGB3BP antibody Background: ITGB3BP is a transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of...
Rabbit polyclonal JAK3 antibody Background: JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases, which is involved in cytokine receptor-mediated intracellular signal transduction. JAK3 is predominantly...
Rabbit polyclonal KIAA0319L antibody raised against the middle region of KIAA0319L Background: This gene encodes a member of the polycystin protein family. Members of this protein family may function in...
Rabbit polyclonal KIRREL2 antibody Background: KIRREL2 is a single-pass type I membrane protein. KIRREL2 protein is a beta-cell-expressed Ig domain protein and may be involved in pancreas development or beta...
Rabbit polyclonal KITLG antibody raised against the middle region of KITLG Background: KITLG is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic...
Rabbit polyclonal KLRA1 antibody raised against the N terminal of KLRA1 Background: Ly-49 Receptors or killer cell lectin-like receptor subfamily A (KLRA), member 1, are a class of natural killer...
Rabbit polyclonal KLRF1 antibody raised against the middle region of KLRF1 Background: KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and...
Rabbit polyclonal Laminin Beta 1 antibody raised against the middle region of LAMB1 Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They...
Rabbit polyclonal Laminin Beta 3 antibody raised against the middle region of LAMB3 Background: The product encoded by this gene is a laminin that belongs to a family of basement...
Rabbit polyclonal Laminin Gamma 1 antibody Background: Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds...
Rabbit polyclonal LBP antibody raised against the C terminal of LBP Background: LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide...
Rabbit polyclonal LBP antibody raised against the middle region of LBP Background: LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide...
Rabbit polyclonal LEFTY1 antibody raised against the N terminal of LEFTY1 Background: LEFTY1 is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a...
Rabbit polyclonal LEFTY2 antibody raised against the N terminal of LEFTY2 Background: LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role...
Rabbit polyclonal Leptin antibody raised against the middle region of LEP Background: LEP is a protein that is secreted by white adipocytes, and which plays a major role in the...
Rabbit polyclonal Leptin antibody raised against the N terminal of LEP Background: LEP is a protein that is secreted by white adipocytes, and which plays a major role in the...
Rabbit polyclonal LGALS1 antibody Background: The galectins are a family of beta-galactoside-bin ding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS1 may act as an autocrine negative growth factor...
Rabbit polyclonal LGALS3BP antibody raised against the middle region of LGALS3BP Background: The galectins are a family of beta-galactoside-bin ding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has...
Rabbit polyclonal LGALS9 antibody Background: The galectins are a family of beta-galactoside-bin ding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS9 is an S-type lectin. It is overexpressed in...
Rabbit polyclonal LIF antibody Background: LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia...
Rabbit polyclonal Lipocalin 1 antibody Background: LCN1 could play a role in taste reception. LCN1 could be necessary for the concentration and delivery of sapid molecules in the gustatory system.
Rabbit polyclonal LONRF2 antibody raised against the middle region of LONRF2 Background: LONRF2 contains 1 Lon domain,1 RING-type zinc finger and 6 TPR repeats. The function of the LONRF2 protein...
Rabbit polyclonal LSAMP antibody raised against the N terminal of LSAMP Background: LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system. During development...
Rabbit polyclonal LTA4H antibody raised against the middle region of LTA4H Background: LTA4H hydrolyzes an epoxide moiety of leukotriene A4 (LTA-4) to form leukotriene B4 (LTB-4). The enzyme also has...
Rabbit polyclonal LYVE1 antibody raised against the N terminal of LYVE1 Background: LYVE1 is a type I integral membrane glycoprotein. It acts as a receptor and binds to both soluble...
Rabbit polyclonal MAP3K11 antibody raised against the middle region of MAP3K11 Background: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a...
Rabbit polyclonal MAP3K2 antibody raised against the N terminal of MAP3K2 Background: MAP3K2 is a component of a protein kinase signal transduction cascade. It regulates the JNK and ERK5 pathways...
Rabbit polyclonal MAP3K7IP1 antibody raised against the N terminal of MAP3K7IP1 Background: The protein encoded by this gene was identified as a regulator of the MAP kinase MAP3K7/TAK1, which is...
Rabbit polyclonal MAP4K2 antibody raised against the N terminal of MAP4K2 Background: MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues,...
Rabbit polyclonal MAP4K4 antibody raised against the N terminal of MAP4K4 Background: MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines...
Rabbit polyclonal MAP4K5 antibody raised against the middle region of MAP4K5 Background: MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN...
Rabbit polyclonal MAPT antibody raised against the middle region of MAPT Background: MAPT is differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. The...
Rabbit polyclonal MASP2 antibody raised against the N terminal of MASP2 Background: The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed...
Rabbit polyclonal Mesothelin antibody raised against the middle region of MSLN Background: An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named...
Rabbit polyclonal MFAP4 antibody raised against the N terminal of MFAP4 Background: MFAP4 is a protein with similarity to a bovine microfibril-associat ed protein. The protein has binding specificities for...
Rabbit polyclonal MICA antibody raised against the N terminal of MICA Background: MICA is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate...
Rabbit polyclonal MKNK2 antibody raised against the N terminal of MKNK2 Background: MKNK2 may play a role in the response to environmental stress and cytokines. It appears to regulate transcription...
Rabbit polyclonal MPZL2 antibody raised against the N terminal of MPZL2 Background: Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene...
Rabbit polyclonal MTL5 antibody Background: Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may...
Rabbit polyclonal MYBPC2 antibody raised against the N terminal of MYBPC2 Background: MYBPC2 encodes a member of the myosin-binding protein family C family. Myosin-binding protein C is a myosin-associated protein...
Rabbit polyclonal MYBPH antibody raised against the N terminal of MYBPH Background: MYBPH binds to myosin; probably involved in interaction with thick myofilaments in the A-band.
Rabbit polyclonal MYD88 antibody Background: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential...
Rabbit polyclonal Myxovirus antibody raised against the C terminal of MX1 Background: In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. MX1...
Rabbit polyclonal NCF4 antibody raised against the middle region of NCF4 Background: NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host...
Rabbit polyclonal NCF4 antibody raised against the N terminal of NCF4 Background: NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host...
Rabbit polyclonal NDP antibody Background: NDP activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. NDP plays a central role in retinal vascularization by acting as a ligand...
Rabbit polyclonal NEDD9 antibody raised against the middle region of NEDD9 Background: Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the...
Rabbit polyclonal NEK6 antibody Background: The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of...
Rabbit polyclonal NEURL2 antibody Background: NEURL2 contains 1 NHR (neuralized homology repeat) domain and 1 SOCS box domain. NEURL2 plays an important role in the process of myofiber differentiation and...
Rabbit polyclonal NID2 antibody Background: Basement membranes, which are composed of type IV collagens, laminins, perlecan, and nidogen, are thin pericellular protein matrices that control a large number of cellular...
Rabbit polyclonal Ninjurin 1 antibody raised against the N terminal of NINJ1 Background: NINJ1 is a homophilic cell adhesion molecule that promotes axonal growth. NINJ1 may play a role in...
Rabbit polyclonal NKIRAS1 antibody raised against the N terminal of NKIRAS1 Background: NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the...
Rabbit polyclonal NKIRAS2 antibody raised against the C terminal of NKIRAS2 Background: NPAL2 is a multi-pass membrane protein and it belongs to the NIPA family. The exact function of NPAL2...
Rabbit polyclonal NKIRAS2 antibody raised against the middle region of NKIRAS2 Background: NPAL2 is a multi-pass membrane protein and it belongs to the NIPA family. The exact function of NPAL2...
Rabbit polyclonal NLGN4X antibody raised against the middle region of NLGN4X Background: NLGN4X is a member of a family of neuronal cell surface proteins. Members of this family may act...
Rabbit polyclonal NLGN4X antibody raised against the N terminal of NLGN4X Background: NLGN4X is a member of a family of neuronal cell surface proteins. Members of this family may act...
Rabbit polyclonal NMBR antibody raised against the N terminal of NMBR Background: Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and...
Rabbit polyclonal NPHP1 antibody Background: Together with Cas NPHP1 may play a role in the control of epithelial cell polarity. NPHP1 seems to help to recruit protein tyrosine kinase 2...
Rabbit polyclonal NPY1R antibody raised against the middle region of NPY1R Background: Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a...
Rabbit polyclonal NR3C1 antibody raised against the N terminal of NR3C1 Background: NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator...
Rabbit polyclonal NRG1 antibody raised against the middle region of NRG1 Background: Neuregulin 1 (NRG1) was originally identified as a 44 kDa glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine...
Rabbit polyclonal NRG1 antibody raised against the N terminal of NRG1 Background: Neuregulin 1 (NRG1) was originally identified as a 44 kDa glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine...
Rabbit polyclonal NRG3 antibody raised against the middle region of NRG3 Background: Neuregulins are a family of growth and differentiation factors that are related to epidermal growth factor.
Rabbit polyclonal NTF5 antibody raised against the N terminal Of Ntf5 Background: This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of...
Rabbit polyclonal OAS1 antibody raised against the C terminal of OAS1 Background: OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to...
Rabbit polyclonal OAS1 antibody raised against the N terminal of OAS1 Background: This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response...
Rabbit polyclonal OAS2 antibody raised against the middle region of OAS2 Background: OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to...
Rabbit polyclonal OAS2 antibody raised against the N terminal of OAS2 Background: OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to...
Rabbit polyclonal OASL antibody raised against the middle region of OASL Background: OASL does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.
Rabbit polyclonal OASL antibody raised against the N terminal of OASL Background: OASL does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.
Rabbit polyclonal OSGIN1 antibody raised against the N terminal of OSGIN1 Background: OSGIN1 regulates the differentiation and proliferation of normal cells through the regulation of cell death.
Rabbit polyclonal Osteomodulin antibody raised against the middle region of OMD Background: OMD may be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-inte grin.
Rabbit polyclonal OTUD6B antibody raised against the middle region of OTUD6B Background: Deubiquitinating enzymes are proteases that specifically cleave ubiquitin linkages, negating the action of ubiquitin ligases. DUBA5 belongs to...
Rabbit polyclonal PARK7 antibody Background: PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a...
Rabbit polyclonal PARVB antibody raised against the C terminal of PARVB Background: Members of the parvin family, including PARVB, are actin-binding proteins associated with focal contacts.Members of the parvin family,...
Rabbit polyclonal PARVB antibody raised against the N terminal of PARVB Background: Members of the parvin family, including PARVB, are actin-binding proteins associated with focal contacts.Members of the parvin family,...
Rabbit polyclonal PCDH1 antibody raised against the N terminal of PCDH1 Background: PCDH1 belongs to the protocadherin subfamily within the cadherin superfamily. It is a membrane protein found at cell-cell...
Rabbit polyclonal PCDH12 antibody raised against the middle region of PCDH12 Background: PCDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular...
Rabbit polyclonal PCDH8 antibody raised against the middle region of PCDH8 Background: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral...
Rabbit polyclonal PCDHA10 antibody raised against the N terminal of PCDHA10 Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly...
Rabbit polyclonal PCDHA12 antibody raised against the N terminal of PCDHA12 Background: PCDHA12 is a potential calcium-dependent cell-adhesion protein. PCDHA12 may be involved in the establishment and maintenance of specific...
Rabbit polyclonal PCDHA3 antibody raised against the N terminal of PCDHA3 Background: PCDHA3 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA3 is a potential calcium-dependent...
Rabbit polyclonal PCDHA4 antibody raised against the C terminal of PCDHA4 Background: The gene encoding PCDHA4 is a member of the protocadherin alpha gene cluster, one of three related gene...
Rabbit polyclonal PCDHA4 antibody raised against the N terminal of PCDHA4 Background: The gene encoding PCDHA4 is a member of the protocadherin alpha gene cluster, one of three related gene...
Rabbit polyclonal PCDHA5 antibody raised against the N terminal of PCDHA5 Background: The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene...
Rabbit polyclonal PCDHA6 antibody raised against the C terminal of PCDHA6 Background: PCDHA6 contains 6 cadherin domains. It is a potential calcium-dependent cell-adhesion protein. PCDHA6 may be involved in the...
Rabbit polyclonal PCDHAC1 antibody raised against the N terminal of PCDHAC1 Background: PCDHAC1 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked...
Rabbit polyclonal PCDHAC2 antibody raised against the N terminal of PCDHAC2 Background: PCDHAC2 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific...
Rabbit polyclonal PCDHB13 antibody raised against the middle region of PCDHB13 Background: PCDHB13 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked...
Rabbit polyclonal PCDHGA4 antibody raised against the N terminal of PCDHGA4 Background: PCDHGA4 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGA4 is a potential calcium-dependent...
Rabbit polyclonal PCDHGB1 antibody raised against the N terminal of PCDHGB1 Background: PCDHGB1 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGB1 is a potential calcium-dependent...
Rabbit polyclonal PCDHGC3 antibody raised against the C terminal of PCDHGC3 Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked...
Rabbit polyclonal PCDHGC3 antibody raised against the N terminal of PCDHGC3 Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked...
Rabbit polyclonal PCDHGC4 antibody raised against the N terminal of PCDHGC4 Background: PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion...
Rabbit polyclonal PDCD7 antibody raised against the middle region of PDCD7 Background: PDCD7 is a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In...
Rabbit polyclonal PDCD7 antibody raised against the N terminal of PDCD7 Background: PDCD7 is a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In...
Rabbit polyclonal PDCD8 antibody raised against the C terminal Of Pdcd8 Background: AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial...
Rabbit polyclonal PDGFD antibody raised against the N terminal of PDGFD Background: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members...
Rabbit polyclonal PDK1 antibody raised against the middle region of PDK1 Background: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one...
Rabbit polyclonal PEA15 antibody raised against the middle region of PEA15 Background: PEA15 is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes.PEA15...
Rabbit polyclonal PENK antibody raised against the middle region of PENK Background: Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a...
Rabbit polyclonal Perforin 1 antibody Background: PRF1 has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically...
Rabbit polyclonal PF4V1 antibody raised against the middle region of PF4V1 Background: PF4V1 is the inhibitor of angiogenesis. PF4V1 is the inhibitor of endothelial cell chemotaxis (in vitro).
Rabbit polyclonal PHLDA2 antibody raised against the middle region of PHLDA2 Background: This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to...
Rabbit polyclonal Plakophilin 2 antibody raised against the N terminal of PKP2 Background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous...
Rabbit polyclonal PLCD1 antibody raised against the N terminal of PLCD1 Background: Phosphoinositide-spe cific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol...
Rabbit polyclonal PLEK antibody raised against the N terminal of PLEK Background: PLEK is a major protein kinase C substrate of platelets, its exact function is not known.
Rabbit polyclonal PLUNC antibody raised against the middle region of PLUNC Background: PLUNC is the human homolog of murine plunc and is specifically expressed in the upper airways and nasopharyngeal...
Rabbit polyclonal PNN antibody raised against the middle region of PNN Background: PNN is the transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the...
Rabbit polyclonal PNN antibody raised against the N terminal of PNN Background: PNN is the transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the...
Rabbit polyclonal PNOC antibody raised against the middle region of PNOC Background: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the...
Rabbit polyclonal POSTN antibody raised against the middle region of POSTN Background: POSTN binds to heparin. It induces cell attachment and spreading and plays a role in cell adhesion. POSTN...
Rabbit polyclonal POSTN antibody raised against the N terminal of POSTN Background: POSTN binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. POSTN may...
Rabbit polyclonal PPARGC1B antibody raised against the N terminal of PPARGC1B Background: The protein encoded by this genetimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor...
Rabbit polyclonal PPM1A antibody Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative...
Rabbit polyclonal PPP1R13B antibody Background: PPP1R13B is a member of the ASPP (apoptosis-stimulati ng protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an...
Rabbit polyclonal PPP2R1A antibody Background: PPP2R1A is a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated...
Rabbit polyclonal PPP2R1B antibody Background: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is...
Rabbit polyclonal PRDX5 antibody raised against the middle region of PRDX5 Background: PRDX5 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides.
Rabbit polyclonal PRKAA1 antibody raised against the middle region of PRKAA1 Background: PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activat ed protein...
Rabbit polyclonal PRKAA1 antibody raised against the N terminal of PRKAA1 Background: PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activat ed protein...
Rabbit polyclonal PRKCB1 antibody raised against the N terminal of PRKCB1 Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by...
Rabbit polyclonal PRKCG antibody raised against the middle region of PRKCG Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by...
Rabbit polyclonal PRKCG antibody raised against the N terminal of PRKCG Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by...
Rabbit polyclonal PRKRA antibody raised against the middle region of PRKRA Background: PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed...
Rabbit polyclonal PRKRA antibody raised against the N terminal of PRKRA Background: PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed...
Rabbit polyclonal Protein S antibody Background: PROS1 is an anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It...
Rabbit polyclonal PSMB10 antibody Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure.
Rabbit polyclonal PSMB9 antibody raised against the C terminal of PSMB9 Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg,...
Rabbit polyclonal PSME1 antibody raised against the middle region of PSME1 Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a...
Rabbit polyclonal PTK2B antibody raised against the C terminal of PTK2B Background: PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation...
Rabbit polyclonal PTK6 antibody raised against the middle region of PTK6 Background: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular...
Rabbit polyclonal PTPLAD1 antibody raised against the N terminal of PTPLAD1 Background: PTPLAD1 is a multi-pass membrane protein. It belongs to the PTPLA family and contains 1 CS domain. PTPLAD1...
Rabbit polyclonal PTX3 antibody raised against the N terminal of PTX3 Background: PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components...
Rabbit polyclonal RAB11B antibody raised against the C terminal of RAB11B Background: RAB11B possesses GTPase activity.
Rabbit polyclonal RAB15 antibody raised against the N terminal of RAB15 Background: RAB15 may act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve...
Rabbit polyclonal RAB18 antibody raised against the C terminal of RAB18 Background: RAB18 belongs to the small GTPase superfamily.
Rabbit polyclonal RAB23 antibody raised against the N terminal of RAB23 Background: The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved...
Rabbit polyclonal RAB26 antibody raised against the N terminal of RAB26 Background: RAB26 belongs to the small GTPase superfamily, Rab family. It participates in exocrine secretion: regulates the secretion of...
Rabbit polyclonal RAB27A antibody raised against the middle region of RAB27A Background: The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound...
Rabbit polyclonal RAB38 antibody raised against the N terminal of RAB38 Background: RAB38 may be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.
Rabbit polyclonal RAB39B antibody raised against the N terminal of RAB39B Background: RAB39B may be involved in vesicular trafficking.
Rabbit polyclonal RAB40A antibody raised against the middle region of RAB40A Background: RAB40A belongs to the small GTPase superfamily, Rab family. It contains 1 SOCS box domain. RAB40A may be...
Rabbit polyclonal RAB40B antibody raised against the middle region of RAB40B Background: RAB40B has similarity to a yeast protein which suggests a role of the gene product in regulating secretory...
Rabbit polyclonal RAB5A antibody raised against the middle region of RAB5A Background: RAB5A is required for the fusion of plasma membranes and early endosomes.
Rabbit polyclonal RAB5B antibody raised against the N terminal of RAB5B Background: RAB5B play a role in protein transport. RAB5B is probably involved in vesicular traffic.
Rabbit polyclonal RABL4 antibody raised against the C terminal of RABL4 Background: RABL4 belongs to the small GTPase superfamily, Ras family. RABL4 possesses GTPase activity By similarity.
Rabbit polyclonal RALGPS1 antibody raised against the middle region of RALGPS1 Background: RALGPS1 contains 1 PH domain and 1 Ras-GEF domain. RALGPS1 may be involved in cytoskeletal organization. It may...
Rabbit polyclonal RanBP3 antibody raised against the N terminal of RANBP3 Background: RANBP3 is a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This...
Rabbit polyclonal RAPGEF1 antibody Background: RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of...
Rabbit polyclonal RASGEF1A antibody raised against the N terminal of RASGEF1A Background: RASGEF1A is the guanine nucleotide exchange factor (GEF) for KRAS, HRAS, and NRAS (in vitro). It plays a...
Rabbit polyclonal RASGEF1C antibody raised against the middle region of RASGEF1C Background: RASGEF1C is the guanine nucleotide exchange factor (GEF).
Rabbit polyclonal RASGEF1C antibody raised against the N terminal of RASGEF1C Background: RASGEF1C is a guanine nucleotide exchange factor (GEF).
Rabbit polyclonal RASGRF1 antibody raised against the N terminal of RASGRF1 Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae...
Rabbit polyclonal RASGRP2 antibody Background: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs,...
Rabbit polyclonal RASL10A antibody raised against the N terminal of RASL10A Background: The specific function of RASL10A is not yet known.
Rabbit polyclonal RASL12 antibody raised against the N terminal of RASL12 Background: The function of RASL12 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal RBJ antibody raised against the middle region of RBJ Background: The function of RBJ protein has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal RCAN3 antibody raised against the middle region of RCAN3 Background: RCAN3 inhibits calcineurin-dependen t transcriptional responses by binding to the catalytic domain of calcineurin A. It could play...
Rabbit polyclonal RFT1 antibody Background: N-glycosylation of proteins follows a highly conserved pathway that begins with the synthesis of aMan(5)GlcNAc(2)-dol ichylpyrophosphate (PP-Dol) intermediate on the cytoplasmic side of the endoplasmic...
Rabbit polyclonal RGS11 antibody raised against the middle region of RGS11 Background: RGS11 belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as...
Rabbit polyclonal RGS19 antibody raised against the N terminal of RGS19 Background: G proteins mediate a number of cellular processes. RGS19 belongs to the RGS (regulators of G-protein signaling) family...
Rabbit polyclonal RGS4 antibody raised against the C terminal of RGS4 Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs)...
Rabbit polyclonal RGS6 antibody raised against the C terminal of RGS6 Background: Members of the RGS (regulator of G protein signaling) family, such as RGS6, modulate G protein function by...
Rabbit polyclonal RGS6 antibody raised against the N terminal of RGS6 Background: Members of the RGS (regulator of G protein signaling) family, such as RGS6, modulate G protein function by...
Rabbit polyclonal RGS9 antibody raised against the middle region of RGS9 Background: RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins...
Rabbit polyclonal RHEB antibody raised against the middle region of RHEB Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with...
Rabbit polyclonal RHEBL1 antibody raised against the middle region of RHEBL1 Background: RHEBL1 binds GTP and exhibits intrinsic GTPase activity. It may activate NF-kappa-B-mediated gene transcription. RHEBL1 promotes signal transduction...
Rabbit polyclonal RHOA antibody raised against the middle region of RHOA Background: RHOA regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin...
Rabbit polyclonal RHOBTB1 antibody raised against the middle region of RHOBTB1 Background: RHOBTB1 belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich...
Rabbit polyclonal RHOC antibody raised against the N terminal of RHOC Background: RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active...
Rabbit polyclonal RHOD antibody raised against the C terminal of RHOD Background: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They...
Rabbit polyclonal RHOD antibody raised against the N terminal of RHOD Background: Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They...
Rabbit polyclonal RHOT1 antibody raised against the middle region of RHOT1 Background: Mitochondrial GTPase involved in mitochondrial trafficking. RHOT1 is probably involved in control of anterograde transport of mitochondria and...
Rabbit polyclonal RHOT1 antibody raised against the N terminal of RHOT1 Background: Mitochondrial GTPase involved in mitochondrial trafficking. RHOT1 is probably involved in control of anterograde transport of mitochondria and...
Rabbit polyclonal RHOU antibody raised against the C terminal of RHOU Background: RHOU is a member of the Rho family of GTPases. It can activate PAK1 and JNK1, and can...
Rabbit polyclonal ROM1 antibody raised against the middle region of ROM1 Background: ROM1 is an integral membrane protein found in the photoreceptor disk rim of the eye. It can form...
Rabbit polyclonal RPS6KA2 antibody raised against the middle region of RPS6KA2 Background: RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation...
Rabbit polyclonal RPSA antibody raised against the middle region of RPSA Background: RPSA is required for the assembly and/or stability of the 40S ribosomal subunit. RPSA is also required for...
Rabbit polyclonal RRAD antibody raised against the middle region of RRAD Background: RRAD may play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents.
Rabbit polyclonal S100A9 antibody raised against the N terminal of S100A9 Background: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand...
Rabbit polyclonal SAA4 antibody raised against the middle region of SAA4 Background: SAA4 is a major acute phase reactant. It is an Apolipoprotein of the HDL complex.
Rabbit polyclonal SAC antibody raised against the N terminal Of Sac Background: SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein...
Rabbit polyclonal SAMHD1 antibody raised against the middle region of SAMHD1 Background: SAMHD1 contains 1 HD domain and 1 SAM (sterile alpha motif) domain. SAMHD1 may play a role in...
Rabbit polyclonal Sarcospan antibody Background: SSPN is a member of the dystrophin-glycoprot ein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and...
Rabbit polyclonal SCOTIN antibody raised against the middle region of Scotin Background: This protein can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.
Rabbit polyclonal SCYE1 antibody Background: SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The...
Rabbit polyclonal SDCBP2 antibody Background: SDCBP2 contains 2 PDZ (DHR) domains. The function of SDCBP2 remains unknown.
Rabbit polyclonal SELS antibody raised against the middle region of SELS Background: SELS is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded...
Rabbit polyclonal Sequestosome 1 antibody raised against the middle region of SQSTM1 Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B...
Rabbit polyclonal SERPINA3 antibody raised against the middle region of SERPINA3 Background: SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein...
Rabbit polyclonal SERPINB2 antibody Background: SERPINB2 inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Rabbit polyclonal SFTPD antibody raised against the middle region of SFTPD Background: SFTPD contributes to the lung's defense against inhaled microorganisms. SFTPD may participate in the extracellular reorganization or turnover...
Rabbit polyclonal SGK1 antibody raised against the N terminal of SGK1 Background: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase...
Rabbit polyclonal SGK3 antibody raised against the N terminal of SGK3 Background: This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX...
Rabbit polyclonal SH2B1 antibody raised against the middle region of SH2B1 Background: SH2B1 is a member of the SH2-domain containing mediators family. SH2B1 mediates activation of various kinases and may...
Rabbit polyclonal SH2D3C antibody raised against the N terminal of SH2D3C Background: SH2D3C is an Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1...
Rabbit polyclonal SH3BP2 antibody raised against the middle region of SH3BP2 Background: SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The...
Rabbit polyclonal SHB antibody raised against the N terminal of SHB Background: SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling...
Rabbit polyclonal SIGLEC10 antibody raised against the middle region of SIGLEC10 Background: SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3-...
Rabbit polyclonal SIGLEC12 antibody raised against the N terminal of SIGLEC12 Background: Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They...
Rabbit polyclonal SIGLEC6 antibody raised against the C terminal of SIGLEC6 Background: SIGLEC6 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds to alpha-2,6-linked sialic...
Rabbit polyclonal SIGLEC6 antibody raised against the middle region of SIGLEC6 Background: SIGLEC6 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds to alpha-2,6-linked sialic...
Rabbit polyclonal SIGLEC6 antibody raised against the N terminal of SIGLEC6 Background: SIGLEC6 is a Putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds to alpha-2,6-linked sialic...
Rabbit polyclonal SIGLEC7 antibody raised against the middle region of SIGLEC7 Background: SIGLEC7 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. In the immune response, it...
Rabbit polyclonal SIGLEC9 antibody raised against the C terminal of SIGLEC9 Background: SIGLEC9 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3-...
Rabbit polyclonal SIPA1 antibody raised against the middle region of SIPA1 Background: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP...
Rabbit polyclonal SKAP1 antibody raised against the N terminal of SKAP1 Background: SKAP1 Is a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting...
Rabbit polyclonal SLC12A4 antibody Background: SLC12A4 mediates electroneutral potassium-chloride cotransport when activated by cell swelling. SLC12A4 may contribute to cell volume homeostasis in single cells.
Rabbit polyclonal SLC20A1 antibody Background: Retrovirus receptors allow infection of human and murine cells by various retroviruses. The receptors that have been identified at the molecular level include CD4 for...
Rabbit polyclonal SLIT3 antibody Background: SLIT3 may act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
Rabbit polyclonal SNAG1 antibody raised against the N terminal Of Snag1 Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX)...
Rabbit polyclonal SNX5 antibody raised against the N terminal of SNX5 Background: SNX5 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain,...
Rabbit polyclonal SNX7 antibody raised against the middle region of SNX7 Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX)...
Rabbit polyclonal SOCS1 antibody raised against the middle region of SOCS1 Background: SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS),...
Rabbit polyclonal SOCS7 antibody raised against the N terminal of SOCS7 Background: SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis...
Rabbit polyclonal SOD2 antibody raised against the N terminal of SOD2 Background: SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a...
Rabbit polyclonal SPON2 antibody raised against the middle region of SPON2 Background: SPON2 is a cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to...
Rabbit polyclonal SPON2 antibody raised against the N terminal of SPON2 Background: SPON2 is a cell adhesion protein that promote adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to...
Rabbit polyclonal SPP1 antibody Background: The SPP1 gene encodes an acidic matrix protein, mainly expressed in mineralized tissues, kidney and atherosclerotic vessels. This protein also contributes to several steps in...
Rabbit polyclonal SSX2IP antibody raised against the middle region of SSX2IP Background: SSX2IP belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic...
Rabbit polyclonal STAMBP antibody raised against the N terminal of STAMBP Background: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule...
Rabbit polyclonal STC1 antibody raised against the N terminal of STC1 Background: STC1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have...
Rabbit polyclonal STK38 antibody raised against the C terminal of STK38 Background: STK38 belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family. It contains 1 AGC-kinase C-terminal domain...
Rabbit polyclonal Symplekin antibody raised against the middle region of SYMPK Background: SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein...
Rabbit polyclonal Symplekin antibody raised against the N terminal of SYMPK Background: SYMPK is a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein...
Rabbit polyclonal TAP1 antibody Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-...
Rabbit polyclonal TAPBP antibody Background: TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing...
Rabbit polyclonal TBK1 antibody raised against the middle region of TBK1 Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it...
Rabbit polyclonal TBK1 antibody raised against the N terminal of TBK1 Background: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it...
Rabbit polyclonal TBL3 antibody Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of...
Rabbit polyclonal TDO2 antibody raised against the N terminal of TDO2 Background: Tryptophan 2,3-dioxygenase plays a role in catalyzing the first and rat-limiting step in the kynurenine pathway, the major...
Rabbit polyclonal Tetraspanin 2 antibody raised against the middle region of TSPAN2 Background: TSPAN2 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of...
Rabbit polyclonal Tetraspanin 6 antibody raised against the N terminal of TSPAN6 Background: TSPAN6 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of...
Rabbit polyclonal TFF1 antibody raised against the middle region of TFF1 Background: Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a...
Rabbit polyclonal Thrombopoietin antibody Background: Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation,...
Rabbit polyclonal TIRAP antibody Background: The innate immune system recognises microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns.
Rabbit polyclonal TJP1 antibody Background: TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.
Rabbit polyclonal TLR5 antibody raised against the N terminal of TLR5 Background: TLR5 participates in the innate immune response to microbial agents. It mediates detection of bacterial flagellins. TLR5 acts...
Rabbit polyclonal TLR9 antibody raised against the N terminal of TLR9 Background: TLR9 participates in the innate immune response to microbial agents. TLR9 detects the unmethylated cytidine-phosphate-g uanosine (CpG) motifs...
Rabbit polyclonal TNFSF13B antibody Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for...
Rabbit polyclonal TNFSF18 antibody Background: TNFSF18 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been...
Rabbit polyclonal TOLLIP antibody raised against the C terminal of TOLLIP Background: TOLLIP is component of the signaling pathway of IL-1 and Toll-like receptors. It Inhibits cell activation by microbial...
Rabbit polyclonal TRAF7 antibody raised against the N terminal of TRAF7 Background: Tumor necrosis factor (TNF) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor...
Rabbit polyclonal Transglutaminase 2 antibody Background: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved,...
Rabbit polyclonal TRPC4AP antibody raised against the middle region of TRPC4AP Background: TRPC4AP may participate in the activation of NFKB1 in response to ligation of TNFRSF1A. TRPC4AP could serve as...
Rabbit polyclonal TSHR antibody raised against the N terminal of TSHR Background: TSHR is receptor for thyrothropin. It plays a central role in controlling thyroid cell metabolism. The activity of...
Rabbit polyclonal TSTA3 antibody raised against the N terminal of TSTA3 Background: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions...
Rabbit polyclonal Ubiquitin D antibody raised against the N terminal of UBD Background: UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is...
Rabbit polyclonal ULBP1 antibody raised against the N terminal of ULBP1 Background: ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple...
Rabbit polyclonal UNC84B antibody Background: UNC84B may form a physical interaction between the nuclear envelope and the centrosome.
Rabbit polyclonal UQCRFS1 antibody raised against the N terminal of UQCRFS1 Background: UQCRFS1 is the component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is...
Rabbit polyclonal Uromodulin antibody raised against the middle region of UMOD Background: This gene encodes uromodulin, the most abundant protein in normal urine.
Rabbit polyclonal VGF antibody raised against the middle region of VGF Background: This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor.
Rabbit polyclonal VGF antibody raised against the middle region of VGF Background: VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. It...
Rabbit polyclonal VPREB1 antibody raised against the middle region of VPREB1 Background: VPREB1 belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development,...
Rabbit polyclonal WNK3 antibody raised against the N terminal of WNK3 Background: Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack...
Rabbit polyclonal WWP1 antibody raised against the N terminal of WWP1 Background: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a...
Rabbit polyclonal ZDHHC17 antibody raised against the middle region of ZDHHC17 Background: ZDHHC17 is a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD.

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