Fitzgerald Industries International, Inc. Datasheets for Biological Materials

Biological materials are biocompatible materials, natural or man-made, that comprise a whole or a part of a living structure or biomedical device that performs, augments, or replaces a natural function
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Product Name Notes
Rabbit polyclonal A1BG antibody raised against the N terminal of A1BG Background: A1BG is a plasma glycoprotein of unknown function. It shows sequence similarity to the variable regions of some...
Rabbit polyclonal ABP1 antibody raised against the C terminal of ABP1 Background: ABP1 is a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine...
Rabbit polyclonal ACRV1 antibody raised against the N terminal of ACRV1 Background: ACRV1 is a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis,...
Rabbit polyclonal Afamin antibody raised against the middle region of AFM Background: AFM is a member of the albumin gene family, which is comprised of four genes that localize to...
Rabbit polyclonal AGR2 antibody Background: AGR2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.
Rabbit polyclonal AGXT2 antibody raised against the N terminal of AGXT2 Background: The protein encoded by this gene is a class III pyridoxal-phosphate- dependent mitochondrial aminotransferase. It catalyzes the conversion...
Rabbit polyclonal Albumin antibody raised against the middle region of ALB Background: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily...
Rabbit polyclonal Albumin antibody raised against the N terminal of ALB Background: Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily...
Rabbit polyclonal ALOX15B antibody raised against the middle region of ALOX15B Background: ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production...
Rabbit polyclonal ALPPL2 antibody raised against the middle region of ALPPL2 Background: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific).
Rabbit polyclonal ANAPC10 antibody raised against the N terminal of ANAPC10 Background: ANAPC10 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls...
Rabbit polyclonal ANAPC7 antibody raised against the C terminal of ANAPC7 Background: The anaphase-promoting complex (APC) consists of at least 8 protein subunits, including APC5, CDC27 (APC3), CDC16 (APC6), and...
Rabbit polyclonal ANGPT4 antibody raised against the N terminal of ANGPT4 Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to...
Rabbit polyclonal ANGPTL2 antibody raised against the N terminal of ANGPTL2 Background: Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific...
Rabbit polyclonal ANGPTL5 antibody raised against the N terminal of ANGPTL5 Background: The function of ANGPTL5 has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal APBB2 antibody raised against the middle region of APBB2 Background: APBB2 may modulate the internalization of beta-amyloid precursor protein.
Rabbit polyclonal ApoA-IV antibody raised against the C terminal of APOA4 Background: The gene encoding APOA4 protein contains 3 exons separated by two introns. A sequence polymorphism has been identified...
Rabbit polyclonal ApoE antibody raised against the N terminal of APOE Background: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis...
Rabbit polyclonal ApoH antibody Background: Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a...
Rabbit polyclonal ARSA antibody raised against the N terminal of ARSA Background: The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead...
Rabbit polyclonal ART4 antibody Background: ART4 is a protein that contains a mono-ADP-ribosylatio n (ART) motif. It is a member of the ADP-ribosyltransfera se gene family but enzymatic activity has...
Rabbit polyclonal ART5 antibody raised against the middle region of ART5 Background: The protein encoded by this gene belongs to the ARG-specific ADP-ribosyltransfera se family. Proteins in this family regulate...
Rabbit polyclonal ASAH1 antibody Background: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally.
Rabbit polyclonal ATPIF1 antibody raised against the N terminal of ATPIF1 Background: This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding...
Rabbit polyclonal B3GALNT2 antibody raised against the middle region of B3GALNT2 Background: B3GALNT2 is the beta-1,3-N-acetylgal actosaminyltransfera se active in synthesizing a unique carbohydrate structure, GalNAc-beta-1-3GlcNA c, on N- and...
Rabbit polyclonal BCAT1 antibody raised against the N terminal of BCAT1 Background: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible...
Rabbit polyclonal BCKDHA antibody raised against the N terminal of BCKDHA Background: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains...
Rabbit polyclonal BGN antibody raised against the middle region of BGN Background: The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related...
Rabbit polyclonal BMPER antibody raised against the C terminal of BMPER Background: BMPER contains 1 TIL (trypsin inhibitory-like) domain, 5 VWFC domains and 1 VWFD domain.BMPER is the inhibitor of...
Rabbit polyclonal BTG4 antibody raised against the middle region of BTG4 Background: The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related...
Rabbit polyclonal BUB3 antibody Background: BUB3 is required for kinetochore localization of BUB1.
Rabbit polyclonal C10ORF46 antibody raised against the middle region of C10Orf46 Background: The function of Chromosome 10 ORF protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal C1QTNF4 antibody raised against the middle region of C1QTNF4 Background: The specific function of C1QTNF4 is not yet known.
Rabbit polyclonal C1QTNF7 antibody raised against the middle region of C1QTNF7 Background: The specific function of C1QTNF7 is not yet known.
Rabbit polyclonal C21ORF62 antibody raised against the middle region of C21Orf62 Background: The function of C21orf62 protein has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal C3ORF39 antibody raised against the N terminal Of C3Orf39 Background: The function of Chromosome 3 ORF protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal C3ORF64 antibody raised against the C terminal Of C3Orf64 Background: The function of C3orf64 protein has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal CACNA1G antibody raised against the middle region of CACNA1G Background: Voltage-activated calcium channels can be distinguished based on their voltage-dependence, deactivation, and single-channel conductance.
Rabbit polyclonal CACNG1 antibody raised against the N terminal of CACNG1 Background: L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these...
Rabbit polyclonal CACNG6 antibody raised against the N terminal of CACNG6 Background: CACNG6 is thought to stabilize the calcium channel in an inactivated (closed) state.
Rabbit polyclonal Calreticulin 3 antibody raised against the N terminal of CALR3 Background: Calreticulins, such as CALR3, are Ca(2+)-binding chaperones localized mainly in the endoplasmic/sarcopla smic reticulum.
Rabbit polyclonal Carboxyl Ester Lipase antibody Background: CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.
Rabbit polyclonal Carboxylesterase 7 antibody raised against the middle region of CES7 Background: CES7 belongs to the type-B carboxylesterase/lip ase family. It is involved in the detoxification of xenobiotics and...
Rabbit polyclonal Carboxylesterase 7 antibody raised against the N terminal of CES7 Background: CES7 belongs to the type-B carboxylesterase/lip ase family. It is involved in the detoxification of xenobiotics and...
Rabbit polyclonal Carboxypeptidase A1 antibody Background: Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. Carboxypeptidase...
Rabbit polyclonal Carboxypeptidase B1 antibody Background: Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric...
Rabbit polyclonal Carboxypeptidase B2 antibody Background: Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes...
Rabbit polyclonal Carboxypeptidase E antibody raised against the N terminal of CPE Background: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of...
Rabbit polyclonal Carboxypeptidase N1 antibody raised against the middle region of CPN1 Background: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides...
Rabbit polyclonal Cardiotrophin 1 antibody raised against the N terminal of CTF1 Background: CTF1 induces cardiac myocyte hypertrophy in vitro. It binds to and activates the ILST/gp130 receptor. It belongs...
Rabbit polyclonal CBLN4 antibody raised against the C terminal of CBLN4 Background: Cerebellin is a sixteen aa peptide found mainly in the adrenal medulla, where it has been shown to...
Rabbit polyclonal CCT7 antibody Background: CCT7 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This...
Rabbit polyclonal CDC2 antibody raised against the middle region of CDC2 Background: The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a...
Rabbit polyclonal CDC23 antibody Background: CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of...
Rabbit polyclonal CDC25B antibody Background: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is...
Rabbit polyclonal CDC45L antibody Background: CDC45L was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member...
Rabbit polyclonal CDK5RAP1 antibody raised against the N terminal of CDK5RAP1 Background: Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit,...
Rabbit polyclonal CDKN3 antibody Background: The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been...
Rabbit polyclonal CDT1 antibody raised against the C terminal of CDT1 Background: CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the...
Rabbit polyclonal CENPB antibody raised against the C terminal of CENPB Background: CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived...
Rabbit polyclonal CENPH antibody raised against the middle region of CENPH Background: Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH...
Rabbit polyclonal CENPH antibody raised against the N terminal of CENPH Background: Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH...
Rabbit polyclonal CETP antibody raised against the middle region of CETP Background: CETP involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP...
Rabbit polyclonal CETP antibody raised against the N terminal of CETP Background: CETP involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP...
Rabbit polyclonal CHEK1 antibody Background: CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for...
Rabbit polyclonal CHERP antibody raised against the middle region of CHERP Background: CHERP is involved in calcium homeostasis, growth and proliferation.
Rabbit polyclonal CHI3L1 antibody Background: CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment. CHI3L1 may play a...
Rabbit polyclonal Chondroadherin antibody raised against the middle region of CHAD Background: Chondroadherin is a cartilage matrix protein thought to mediate adhesion of isolated chondrocytes. CHAD contains 11 leucine-rich repeats...
Rabbit polyclonal CHRFAM7A antibody raised against the middle region of CHRFAM7A Background: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal...
Rabbit polyclonal CHRNA1 antibody Background: The CHRNA1 gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating.
Rabbit polyclonal CHRNA3 antibody raised against the N terminal of CHRNA3 Background: The CHRNA3 subunit is expressed in the soma of the majority of pyramidal cells, with the most alpha...
Rabbit polyclonal CHRNA4 antibody raised against the N terminal of CHRNA4 Background: CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a...
Rabbit polyclonal Chromogranin A antibody Background: CHGA is a member of the chromogranin/secreto granin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells.
Rabbit polyclonal CHST6 antibody Background: CHST6 catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. It mediates sulfation of keratan in cornea. Keratan sulfate...
Rabbit polyclonal Chymotrypsin C antibody Background: CTRC is a member of the peptidase S1 family. The protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript...
Rabbit polyclonal Chymotrypsin-Like antibody raised against the N terminal of CTRL Background: CTRL contains 1 F-box domain. It is substrate-recognitio n component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase...
Rabbit polyclonal Chymotrypsin-Like antibody raised against the N terminal of CTRL Background: CTRL possesses serine-type endopeptidase activity.
Rabbit polyclonal CLCNKA antibody raised against the N terminal of CLCNKA Background: CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12...
Rabbit polyclonal CLCNKB antibody raised against the C terminal of CLCNKB Background: Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at...
Rabbit polyclonal Collagen Type I alpha 2 antibody raised against the middle region of COL1A2 Background: COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two...
Rabbit polyclonal CREG2 antibody raised against the N terminal of CREG2 Background: The function of CREG2 has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal CRISP1 antibody raised against the N terminal of CRISP1 Background: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg...
Rabbit polyclonal CRMP1 antibody raised against the C terminal of CRMP1 Background: CRMP1 is a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The protein...
Rabbit polyclonal CRMP1 antibody raised against the N terminal of CRMP1 Background: CRMP1 is a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The protein...
Rabbit polyclonal Cyclin B1 antibody raised against the middle region of CCNB1 Background: CCNB1 is a regulatory protein involved in mitosis. CCNB1 complexes with p34(cdc2) to form the maturation-promoting factor...
Rabbit polyclonal Cyclin Y antibody raised against the middle region of CCNY Background: CCNY belongs to the cyclin family, Cyclin Y subfamily. It contains 1 cyclin N-terminal domain. Single nucleotide...
Rabbit polyclonal Cyclin Y-Like 1 antibody raised against the N terminal of CCNYL1 Background: The specific function of CCNYL1 is not yet known.
Rabbit polyclonal CYP1B1 antibody raised against the middle region of CYP1B1 Background: CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which...
Rabbit polyclonal CYP2B6 antibody raised against the middle region of CYP2B6 Background: This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are...
Rabbit polyclonal CYP2C18 antibody raised against the N terminal of CYP2C18 Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases...
Rabbit polyclonal CYP2C19 antibody raised against the middle region of CYP2C19 Background: CYP2C19 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which...
Rabbit polyclonal CYP2C9 antibody raised against the C terminal of CYP2C9 Background: CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which...
Rabbit polyclonal Decorin antibody raised against the C terminal of DCN Background: DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein.
Rabbit polyclonal Decorin antibody raised against the N terminal of DCN Background: DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein.
Rabbit polyclonal DHRS9 antibody Background: DHRS9 is a 3-alpha-hydroxystero id dehydrogenase that converts 3-alpha-tetrahydropr ogesterone (allopregnanolone) to dihydroxyprogesteron e and 3-alpha-androstanedi ol to dihydroxyprogesteron e.
Rabbit polyclonal DHX16 antibody Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration...
Rabbit polyclonal DKC1 antibody raised against the N terminal of DKC1 Background: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in...
Rabbit polyclonal DNASE2B antibody raised against the middle region of DNASE2B Background: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well...
Rabbit polyclonal DNTT antibody raised against the middle region of DNTT Background: DNTT is the template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of...
Rabbit polyclonal DNTT antibody raised against the N terminal of DNTT Background: DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide...
Rabbit polyclonal DPYSL2 antibody raised against the middle region of DPYSL2 Background: DPYSL2 belongs to the DHOase family. It is necessary for signaling by class 3 semaphorins and subsequent remodeling...
Rabbit polyclonal DPYSL3 antibody raised against the middle region of DPYSL3 Background: DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a...
Rabbit polyclonal Dynactin 2 antibody Background: DCTN2 is a 50 kDa subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin...
Rabbit polyclonal ECHDC2 antibody raised against the middle region of ECHDC2 Background: ECHDC2 belongs to the enoyl-CoA hydratase/isomerase family. The exact function of ECHDC2 remains unknown.
Rabbit polyclonal EFEMP2 antibody raised against the middle region of EFEMP2 Background: A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor...
Rabbit polyclonal EGF antibody Background: Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of...
Rabbit polyclonal EIF4G2 antibody raised against the N terminal of EIF4G2 Background: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F),...
Rabbit polyclonal ENDOG antibody raised against the middle region of ENDOG Background: ENDOG cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, ENDOG also...
Rabbit polyclonal ENPP6 antibody raised against the middle region of ENPP6 Background: ENPP6 is a choline-specific glycerophosphodieste r phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while...
Rabbit polyclonal EPHX1 antibody Background: Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from...
Rabbit polyclonal Epsilon Tubulin 1 antibody raised against the middle region of TUBE1 Background: This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal...
Rabbit polyclonal EPX antibody raised against the middle region of EPX Background: EPX belongs to the peroxidase family, XPO subfamily. Defects in EPX are the cause of eosinophil peroxidase deficiency...
Rabbit polyclonal ERLIN2 antibody raised against the middle region of ERLIN2 Background: ERLIN2 plays an important role in the early steps of the endoplasmic reticulum-associated degradation (ERAD) pathway. It is...
Rabbit polyclonal ESSPL antibody raised against the N terminal of ESSPL Background: The specific function of ESSPL is not yet known.
Rabbit polyclonal Estrogen Receptor 1 antibody raised against the middle region of ESR1 Background: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell...
Rabbit polyclonal Factor II antibody Background: Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of...
Rabbit polyclonal Factor II antibody Background: Coagulation factor II receptor(F2R) is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor.
Rabbit polyclonal Factor XII antibody Background: This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease...
Rabbit polyclonal Factor XIII B Polypeptide antibody raised against the middle region of F13B Background: F13B contains 10 Sushi (CCP/SCR) domains. The B chain of factor XIII is not catalytically...
Rabbit polyclonal Factor XIII B Polypeptide antibody raised against the N terminal of F13B Background: F13B contains 10 Sushi (CCP/SCR) domains. The B chain of factor XIII is not catalytically...
Rabbit polyclonal FBLN1 antibody raised against the N terminal of FBLN1 Background: Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required...
Rabbit polyclonal FCN1 antibody Background: The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a...
Rabbit polyclonal FCN3 antibody raised against the N terminal of FCN3 Background: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human...
Rabbit polyclonal FETUB antibody raised against the N terminal of FETUB Background: The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily...
Rabbit polyclonal FGA antibody raised against the middle region of FGA Background: FGA is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains.
Rabbit polyclonal FGL1 antibody raised against the middle region of FGL1 Background: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of...
Rabbit polyclonal Fibromodulin antibody raised against the N terminal of FMOD Background: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich...
Rabbit polyclonal FKBP2 antibody raised against the N terminal of FKBP2 Background: FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular...
Rabbit polyclonal FLJ37300 antibody raised against the N terminal Of Flj37300 Background: FLJ37300 is a hypothetical protein found on chromosome 17.
Rabbit polyclonal FRK antibody raised against the middle region of FRK Background: FRK belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may...
Rabbit polyclonal FRK antibody raised against the N terminal of FRK Background: The specific function of FRK is not yet known.
Rabbit polyclonal FST antibody raised against the middle region of FST Background: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. Follistatin is a single-chain gonadal protein...
Rabbit polyclonal FUCA1 antibody raised against the middle region of FUCA1 Background: Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least...
Rabbit polyclonal FUCA1 antibody raised against the N terminal of FUCA1 Background: Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least...
Rabbit polyclonal FUT6 antibody raised against the C terminal of FUT6 Background: FUT6 is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin...
Rabbit polyclonal FXYD1 antibody Background: FXYD1 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and...
Rabbit polyclonal FXYD7 antibody raised against the N terminal of FXYD7 Background: This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene...
Rabbit polyclonal GABRA1 antibody Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these...
Rabbit polyclonal GABRA4 antibody Background: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.GABA is...
Rabbit polyclonal GABRA5 antibody Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these...
Rabbit polyclonal GABRB1 antibody Background: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Rabbit polyclonal GABRB2 antibody Background: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene...
Rabbit polyclonal GABRB3 antibody Background: GABRB3 is a member of the ligand-gated ionic channel family. GABRB3 is one of at least 13 distinct subunits of a multisubunit chloride channel that...
Rabbit polyclonal GABRE antibody Background: GABRE belongs to the ligand-gated ionic channel family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the...
Rabbit polyclonal GABRQ antibody Background: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene...
Rabbit polyclonal GABRR1 antibody Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member...
Rabbit polyclonal GABRR2 antibody Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR2 is a member...
Rabbit polyclonal GALNT10 antibody raised against the N terminal Of Galnt10 Background: GALNT10 belongs to the polypeptide N-acetylgalactosamin yltransferase (pp-GalNAc-T) family. Polypeptide GalNAc transferases initiate the synthesis of mucin-type oligosaccharides...
Rabbit polyclonal GAS2L1 antibody raised against the middle region of GAS2L1 Background: GAS2L1, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated...
Rabbit polyclonal Gelsolin antibody Background: GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly...
Rabbit polyclonal GFRA2 antibody raised against the C terminal of GFRA2 Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play...
Rabbit polyclonal GINS2 antibody Background: The yeast heterotetrameric GINS complex is made up of Sld5, Psf1, Psf2, and Psf3. The formation of this complex is essential for the initiation of...
Rabbit polyclonal GLA antibody raised against the N terminal of GLA Background: GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly...
Rabbit polyclonal GLS antibody raised against the middle region of GLS Background: Sahai demonstrated phosphate-activated glutaminase in human platelets. It is the major enzyme yielding glutamate from glutamine.
Rabbit polyclonal GNAO1 antibody raised against the middle region of Gnao1 Background: Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha...
Rabbit polyclonal GNAO1 antibody Background: Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular...
Rabbit polyclonal GPX3 antibody Background: GPX3 belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site.
Rabbit polyclonal GRIK2 antibody raised against the C terminal of GRIK2 Background: This gene, GRIK2, encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory...
Rabbit polyclonal GRIK5 antibody raised against the middle region of GRIK5 Background: GRIK5 is a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory...
Rabbit polyclonal GRIN2A antibody raised against the middle region of GRIN2A Background: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be...
Rabbit polyclonal GRIN2B antibody raised against the middle region of GRIN2B Background: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be...
Rabbit polyclonal GRIN2C antibody raised against the N terminal of GRIN2C Background: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved...
Rabbit polyclonal GSPT2 antibody raised against the N terminal of GSPT2 Background: GSPT2 is closely related to GSPT1, a GTP-binding protein that plays an essential role at the G1- to...
Rabbit polyclonal GSR antibody raised against the N terminal of GSR Background: GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the...
Rabbit polyclonal GSTM1 antibody raised against the N terminal of GSTM1 Background: Cytosolic and membrane-bound forms of glutathione S-transferase are two distinct supergene families. At present, eight distinct classes of...
Rabbit polyclonal GSTM3 antibody Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione...
Rabbit polyclonal GTSE1 antibody raised against the middle region of GTSE1 Background: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with...
Rabbit polyclonal GTSE1 antibody raised against the N terminal of GTSE1 Background: GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with...
Rabbit polyclonal H6PD antibody Background: There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form is autosomally linked. This H form shows activity with other hexose-6-phosphates,...
Rabbit polyclonal Haptoglobin antibody raised against the middle region of HP Background: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine...
Rabbit polyclonal Haptoglobin antibody raised against the N terminal of HP Background: Haptoglobin combines with free plasma hemoglobin, preventing loss of iron through the kidneys and protecting the kidneys from...
Rabbit polyclonal HCN3 antibody raised against the middle region of HCN3 Background: HCN3 is a putative hyperpolarization-ac tivated ion channel exhibiting weak selectivity for potassium over sodium ions.
Rabbit polyclonal HDAC11 antibody raised against the middle region of HDAC11 Background: Histone deacetylases, such as HDAC11, control DNA expression by modifying the core histone octamers that package DNA into...
Rabbit polyclonal HDAC9 antibody raised against the middle region of HDAC9 Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetyl ation alters...
Rabbit polyclonal HECA antibody Background: This gene encodes the homolog of the Drosophila headcase protein, a highly basic, cytoplasmic protein that regulates the re-entry of imaginal cells into the mitotic...
Rabbit polyclonal HERC5 antibody raised against the middle region of HERC5 Background: This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a...
Rabbit polyclonal HERC5 antibody raised against the N terminal of HERC5 Background: HERC5 is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugatin g enzyme in the...
Rabbit polyclonal Hexokinase 2 antibody raised against the N terminal of HK2 Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is...
Rabbit polyclonal HEY1 antibody raised against the middle region of HEY1 Background: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision...
Rabbit polyclonal HEY1 antibody raised against the N terminal of HEY1 Background: Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision...
Rabbit polyclonal HMGCL antibody Background: The HMGCL protein belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a...
Rabbit polyclonal HRG antibody raised against the middle region of HRG Background: This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has...
Rabbit polyclonal HS2ST1 antibody raised against the middle region of HS2ST1 Background: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that...
Rabbit polyclonal HS2ST1 antibody raised against the N terminal of HS2ST1 Background: Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that...
Rabbit polyclonal HS3ST1 antibody Background: HS3ST1 is the rate limiting enzyme for synthesis of HSact. HS3ST1 performs the crucial step modification in the biosynthesis of anticoagulant heparan sulfate (HSact) that...
Rabbit polyclonal HSPA2 antibody raised against the middle region of HSPA2 Background: HSPA2 belongs to the heat shock protein 70 family. In cooperation with other chaperones, HSPA2 stabilize preexistent proteins...
Rabbit polyclonal IFN Alpha 5 antibody raised against the middle region of IFNA5 Background: Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.
Rabbit polyclonal IFN Alpha 7 antibody raised against the N terminal of IFNA7 Background: IFNA7 belongs to the alpha/beta interferon family. IFNA7 is produced by macrophages, IFN-alpha have antiviral activities.
Rabbit polyclonal IGFBP2 antibody raised against the middle region of IGFBP2 Background: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the...
Rabbit polyclonal IGFBP4 antibody raised against the middle region of IGFBP4 Background: IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 is a protein with...
Rabbit polyclonal IGFBP7 antibody raised against the C terminal of IGFBP7 Background: IGFBP7 contains 1 Ig-like C2-type (immunoglobulin-like ) domain, 1 IGFBP N-terminal domain and 1 Kazal-like domain. It binds...
Rabbit polyclonal IL1 alpha antibody raised against the N terminal of IL1A Background: The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic...
Rabbit polyclonal IL1 beta antibody raised against the N terminal of IL1B Background: IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages...
Rabbit polyclonal ILF3 antibody raised against the N terminal of ILF3 Background: ILF3 may facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. ILF3 can act as a translation...
Rabbit polyclonal Inhibin Alpha antibody raised against the N terminal of INHA Background: INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor.
Rabbit polyclonal Jagged 2 antibody raised against the N terminal of JAG2 Background: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members...
Rabbit polyclonal JARID2 antibody raised against the N terminal of JARID2 Background: This gene is an ortholog of the mouse jumonji gene, which encodes a nuclear protein essential for mouse...
Rabbit polyclonal Karyopherin Alpha 2 antibody Background: Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions...
Rabbit polyclonal KCNA1 antibody raised against the middle region of KCNA1 Background: KCNA1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to...
Rabbit polyclonal KCNC4 antibody raised against the middle region of KCNC4 Background: KCNC4 is part of the Shaker gene family of Drosophila. It encodes components of voltage-gated potassium channels and...
Rabbit polyclonal KCNG1 antibody raised against the N terminal of KCNG1 Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural...
Rabbit polyclonal KCNG4 antibody raised against the N terminal of KCNG4 Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural...
Rabbit polyclonal KCNH2 antibody Background: This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this...
Rabbit polyclonal KCNH3 antibody Background: The function of KCNH3 protein has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal KCNH3 antibody Background: This gene encodes a pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current with fast inactivation. Channel properties may be modulated by cAMP...
Rabbit polyclonal KCNJ12 antibody raised against the middle region of KCNJ12 Background: KCNJ12 is an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought...
Rabbit polyclonal KCNJ16 antibody raised against the middle region of KCNJ16 Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses.
Rabbit polyclonal KCNJ9 antibody raised against the middle region of KCNJ9 Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses.
Rabbit polyclonal KCNK1 antibody raised against the middle region of KCNK1 Background: KCNK1 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains.
Rabbit polyclonal KCNK10 antibody raised against the N terminal of KCNK10 Background: KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains.
Rabbit polyclonal KCNK13 antibody raised against the C terminal of KCNK13 Background: KCNK13 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming domains. The...
Rabbit polyclonal KCNK15 antibody raised against the middle region of KCNK15 Background: KCNK15 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains.
Rabbit polyclonal KCNK5 antibody raised against the C terminal of KCNK5 Background: KCNK5 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains.
Rabbit polyclonal KCNK6 antibody raised against the n terminal of KCNK6 Background: KCNK6 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains.
Rabbit polyclonal KCNK9 antibody raised against the N terminal of KCNK9 Background: KCNK9 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains.
Rabbit polyclonal KCNMA1 antibody raised against the middle region of KCNMA1 Background: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth...
Rabbit polyclonal KCNMB3 antibody raised against the middle region of KCNMB3 Background: KCNMB3 is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK...
Rabbit polyclonal KCNN3 antibody raised against the C terminal of KCNN3 Background: Action potentials in vertebrate neurons are followed by an afterhyperpolarizati on (AHP) that may persist for several seconds...
Rabbit polyclonal KCNN4 antibody raised against the C terminal of KCNN4 Background: KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is...
Rabbit polyclonal KCNQ2 antibody raised against the middle region of KCNQ2 Background: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the...
Rabbit polyclonal KCNQ2 antibody raised against the N terminal of KCNQ2 Background: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the...
Rabbit polyclonal KCNQ5 antibody raised against the middle region of KCNQ5 Background: This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions...
Rabbit polyclonal KCNS1 antibody raised against the N terminal of KCNS1 Background: Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both...
Rabbit polyclonal KHDRBS1 antibody raised against the middle region of KHDRBS1 Background: KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once...
Rabbit polyclonal KHDRBS1 antibody raised against the N terminal of KHDRBS1 Background: KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once...
Rabbit polyclonal KIAA1199 antibody raised against the middle region of KIAA1199 Background: KIAA1199 may function as a tumor suppressor.
Rabbit polyclonal KIF12 antibody raised against the N terminal of KIF12 Background: KIF12 is a member of the kinesin superfamily of microtubule-associat ed molecular motors that play important roles in...
Rabbit polyclonal KIF13B antibody raised against the N terminal of KIF13B Background: KIF13B may be involved in reorganization of the cortical cytoskeleton. KIF13B may be functionally important for the intracellular...
Rabbit polyclonal KIF15 antibody raised against the middle region of KIF15 Background: KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.
Rabbit polyclonal KIF1A antibody raised against the N terminal of KIF1A Background: The protein encoded by this gene is a member of the kinesin family. This protein is highly similar...
Rabbit polyclonal KIF21A antibody raised against the N terminal of KIF21A Background: KIF21A belongs to a family of plus end-directed kinesin motor proteins. Neurons use kinesin and dynein microtubule-dependen t...
Rabbit polyclonal KIF22 antibody raised against the N terminal of KIF22 Background: KIF22 a member of kinesin-like protein family. This family of proteins are microtubule-dependen t molecular motors that transport...
Rabbit polyclonal KIF23 antibody raised against the middle region of KIF23 Background: KIF23 is a member of kinesin-like protein family. This family includes microtubule-dependen t molecular motors that transport organelles...
Rabbit polyclonal KIF23 antibody raised against the N terminal of KIF23 Background: KIF23 is a member of kinesin-like protein family. This family includes microtubule-dependen t molecular motors that transport organelles...
Rabbit polyclonal KIF25 antibody raised against the N terminal of KIF25 Background: The protein encoded by the KIF25 gene is a member of the kinesin-like protein family. Protein family members...
Rabbit polyclonal KIF2A antibody raised against the C terminal of KIF2A Background: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependen...
Rabbit polyclonal KIF2A antibody raised against the middle region of KIF2A Background: KIF2A plus end-directed microtubule-dependen t motor is required for normal brain development. KIF2A may regulate microtubule dynamics during...
Rabbit polyclonal KIF2A antibody raised against the N terminal of KIF2A Background: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependen...
Rabbit polyclonal KIF2B antibody raised against the middle region of KIF2B Background: KIF2B is the plus end-directed microtubule-dependen t motor required for spindle assembly and chromosome movement. KIF2B has microtubule...
Rabbit polyclonal KIF2C antibody raised against the N terminal of KIF2C Background: KIF2C is a member of kinesin-like protein family. Proteins of this family are microtubule-dependen t molecular motors that...
Rabbit polyclonal KIF3A antibody raised against the C terminal of KIF3A Background: KIF3A/B is a kinesin involved in intraflagellar transport and Golgi trafficking.
Rabbit polyclonal KIF3B antibody raised against the C terminal of KIF3B Background: The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid...
Rabbit polyclonal KIF3C antibody raised against the middle region of KIF3C Background: KIF3C is a member of KIF3 family. It is highly enriched in neural tissues such as brain, spinal...
Rabbit polyclonal KIF5B antibody raised against the C terminal of KIF5B Background: Kinesin is the founding member of a superfamily of microtubule based motor proteins that perform force-generating tasks such...
Rabbit polyclonal KIF5B antibody raised against the N terminal of KIF5B Background: Kinesin is the founding member of a superfamily of microtubule based motor proteins that perform force-generating tasks such...
Rabbit polyclonal KIF9 antibody raised against the n terminal of KIF9 Background: KIF9 acts as a regulator of podosomes and of podosomal matrix degradation in primary human macrophages.
Rabbit polyclonal KIFC2 antibody raised against the N terminal of KIFC2 Background: Members of the kinesin superfamily of microtubule-associat ed proteins are involved in a variety of intracellular processes including...
Rabbit polyclonal KIFC3 antibody raised against the C terminal of KIFC3 Background: KIFC3 belongs to the kinesin-like protein family. It contains 1 kinesin-motor domain. KIFC3 is the minus-end microtubule-dependen t...
Rabbit polyclonal KLHDC4 antibody raised against the N terminal of KLHDC4 Background: KLHDC4 is involved in protein binding.
Rabbit polyclonal KLK10 antibody raised against the N terminal of KLK10 Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are...
Rabbit polyclonal KRAS antibody raised against the N terminal of KRAS Background: KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an...
Rabbit polyclonal LAIR2 antibody raised against the N terminal of LAIR2 Background: LAIR2 is a member of the immunoglobulin superfamily. It was identified by its similarity to LAIR1, an inhibitory...
Rabbit polyclonal LATS1 antibody Background: The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase...
Rabbit polyclonal LGICZ1 antibody raised against the N terminal Of Lgicz1 Background: LGICZ1 is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated...
Rabbit polyclonal LIG1 antibody raised against the middle region of LIG1 Background: LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in...
Rabbit polyclonal Lipase antibody (Gastric) raised against the N terminal of LIPF Background: This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal...
Rabbit polyclonal Lipocalin 12 antibody raised against the N terminal of LCN12 Background: LCN12 may play a role in male fertility. LCN12 may act as a retinoid carrier protein within...
Rabbit polyclonal Lipocalin 6 antibody raised against the middle region of LCN6 Background: LCN6 may play a role in male fertility.
Rabbit polyclonal LOC51057 antibody raised against the N terminal of LOC51057 Background: The function of LOC51057 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal LOC552891 antibody raised against the N terminal of LOC552891 Background: The function of the LOC552891 protein has not been widely studied, and is yet to be fully elucidated.
Rabbit polyclonal LOXL1 antibody raised against the middle region of LOXL1 Background: LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to...
Rabbit polyclonal LOXL1 antibody raised against the N terminal of LOXL1 Background: LOXL1 is a member of the lysyl oxidase family. The prototypic member of the family is essential to...
Rabbit polyclonal LRDD antibody raised against the middle region of LRDD Background: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been...
Rabbit polyclonal LRDD antibody raised against the N terminal of LRDD Background: The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been...
Rabbit polyclonal LYPD4 antibody raised against the N terminal of LYPD4 Background: The specific function of LYPD4 is not yet known.
Rabbit polyclonal LYPD6 antibody raised against the middle region of LYPD6 Background: LYPD6 contains 1 UPAR/Ly6 domain. The exact function of LYPD6 is not known.
Rabbit polyclonal LYZL6 antibody raised against the N terminal of LYZL6 Background: LYZL6 belongs to the glycosyl hydrolase 22 family. The exact function of LYZL6 remains unknown.
Rabbit polyclonal LZTS2 antibody raised against the N terminal of LZTS2 Background: LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. LZTS2 is required for...
Rabbit polyclonal MAPK12 antibody raised against the N terminal of MAPK12 Background: Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals.
Rabbit polyclonal MAPK13 antibody raised against the middle region of MAPK13 Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as...
Rabbit polyclonal MAPK3 antibody raised against the middle region of MAPK3 Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known...
Rabbit polyclonal MAPK4 antibody raised against the middle region of MAPK4 Background: Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors...
Rabbit polyclonal Matrilin 1 antibody raised against the middle region of MATN1 Background: This gene encodes a member of von Willebrand factor A domain containing protein family. This family of...
Rabbit polyclonal Matrilin 3 antibody raised against the middle region of MATN3 Background: This gene encodes a member of von Willebrand factor A domain containing protein family. This family of...
Rabbit polyclonal Matrilin 3 antibody raised against the N terminal of MATN3 Background: This gene encodes a member of von Willebrand factor A domain containing protein family. This family of...
Rabbit polyclonal MCM10 antibody raised against the middle region of MCM10 Background: This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation...
Rabbit polyclonal MCM2 antibody raised against the middle region of MCM2 Background: This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation...
Rabbit polyclonal MCM3 antibody raised against the C terminal of MCM3 Background: MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of...
Rabbit polyclonal MCM6 antibody raised against the C terminal of MCM6 Background: The protein encoded by the MCM6 gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that...
Rabbit polyclonal MCM7 antibody raised against the middle region of MCM7 Background: MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential...
Rabbit polyclonal MCM8 antibody raised against the C terminal of MCM8 Background: MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of...
Rabbit polyclonal MCM8 antibody raised against the N terminal of MCM8 Background: MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of...
Rabbit polyclonal MCM8 antibody raised against the N terminal of MCM8 Background: This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation...
Rabbit polyclonal MCM9 antibody raised against the N terminal of MCM9 Background: MCM9 is a protein that shares similarity with minichromosome maintenance (MCM) proteins, which are known to be essential...
Rabbit polyclonal MCTS1 antibody raised against the N terminal of MCTS1 Background: MCTS1 is an anti-oncogene that play a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent...
Rabbit polyclonal MFAP2 antibody raised against the N terminal of MFAP2 Background: Microfibrillar-assoc iated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the...
Rabbit polyclonal MFNG antibody raised against the C terminal of MFNG Background: MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate...
Rabbit polyclonal MFNG antibody raised against the middle region of MFNG Background: MFNG is one of the evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate...
Rabbit polyclonal MGP antibody raised against the middle region of MGP Background: MGP is associates with the organic matrix of bone and cartilage. MGP is thought to act as an...
Rabbit polyclonal MIS12 antibody Background: MIS12 is part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis.
Rabbit polyclonal MLH1 antibody Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA...
Rabbit polyclonal MLH3 antibody Background: This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during...
Rabbit polyclonal MMP13 antibody Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the Breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and...
Rabbit polyclonal MMP3 antibody Background: MMP3 can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. MMP3 activates procollagenase.Prote...
Rabbit polyclonal MOS antibody raised against the middle region of MOS Background: MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase...
Rabbit polyclonal MPPED2 antibody raised against the C terminal of MPPED2 Background: MPPED2 protein displays low level metallophosphoestera se activity.
Rabbit polyclonal MPPED2 antibody raised against the N terminal of MPPED2 Background: The specific function of MPPED2 is not yet known.
Rabbit polyclonal MRPL47 antibody raised against the middle region of MRPL47 Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial...
Rabbit polyclonal MSH2 antibody Background: MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of...
Rabbit polyclonal MSH4 antibody Background: MSH4 is involved in meiotic recombination. MSH4 is also required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
Rabbit polyclonal MSH4 antibody Background: MSH4 is involved in meiotic recombination. MSH4 is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
Rabbit polyclonal MSH5 antibody Background: MSH5 is a member of the mutS family of proteins that are involved in DNA mismatch repair or meiotic recombination processes. This protein is similar...
Rabbit polyclonal MSH6 antibody Background: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to...
Rabbit polyclonal MST1 antibody Background: MST1 belongs to the peptidase S1 family, plasminogen subfamily. It contains 4 kringle domains, 1 PAN domain and 1 peptidase S1 domain. MST1 probably has...
Rabbit polyclonal MTR antibody raised against the C terminal of MTR Background: MTR is the enzyme 5-methyltetrahydrofo late-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final...
Rabbit polyclonal NBL1 antibody raised against the middle region of NBL1 Background: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins,...
Rabbit polyclonal NCAPD2 antibody raised against the C terminal of NCAPD2 Background: NCAPD2 is the regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into...
Rabbit polyclonal NCAPH antibody raised against the C terminal of NCAPH Background: NCAPH is a member of the barr family and a regulatory subunit of the condensin complex. This complex...
Rabbit polyclonal NCAPH antibody raised against the N terminal of NCAPH Background: NCAPH is a member of the barr family and a regulatory subunit of the condensin complex. This complex...
Rabbit polyclonal NDN antibody Background: This intronless gene is located in the Prader-Willi syndrome deletion region. It is an imprinted gene and is expressed exclusively from the paternal allele.
Rabbit polyclonal NDUFS3 antibody raised against the middle region of NDUFS3 Background: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in...
Rabbit polyclonal NEK3 antibody Background: NEK3 is a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. It differs from other NimA family members in that...
Rabbit polyclonal NEK9 antibody Background: NEK9 is a pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. NEK9 phosphorylates different histones, myelin basic protein,...
Rabbit polyclonal Nestin antibody raised against the middle region of NES Background: Nestin is an intermediate filament protein. It is expressed predominantly in stem cells of the central nervous system...
Rabbit polyclonal NEURL antibody Background: NEURL may be involved in protein binding, zinc ion binding and metal ion binding.
Rabbit polyclonal NOMO1 antibody raised against the C terminal of NOMO1 Background: NOMO1 was originally thought to be related to the collagenase gene family. This gene is one of three...
Rabbit polyclonal NOMO1 antibody raised against the N terminal of NOMO1 Background: NOMO1 was originally thought to be related to the collagenase gene family. This gene is one of three...
Rabbit polyclonal NPM2 antibody raised against the N terminal of NPM2 Background: NPM2 belongs to the nucleoplasmin family. It probably involved in sperm DNA decondensation during fertilization.
Rabbit polyclonal NR2C2 antibody raised against the N terminal of NR2C2 Background: Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have...
Rabbit polyclonal NR2E1 antibody raised against the middle region of NR2E1 Background: The NR2E1 gene is a member of the steroid nuclear receptor superfamily and is predominately expressed in the...
Rabbit polyclonal Nucleobindin 1 antibody raised against the C terminal of NUCB1 Background: Nucleobindin, also known as calnuc, participates in Ca2+ storage in the Golgi, as well as in other...
Rabbit polyclonal NUDC antibody Background: NudC was first identified as a regulator of nuclear movement in the asexual reproductive cycle of the filamentous fungus Aspergillus nidulans. Human NUDC is a...
Rabbit polyclonal NUP98 antibody raised against the N terminal of NUP98 Background: The nuclear pore complex (NPC) is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98...
Rabbit polyclonal OLFML1 antibody raised against the middle region of OLFML1 Background: The function of OLFML1 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal OLFML1 antibody raised against the N terminal of OLFML1 Background: The function of OLFML1 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal Opticin antibody raised against the C terminal of OPTC Background: Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are...
Rabbit polyclonal ORC4L antibody Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells.
Rabbit polyclonal ORC6L antibody Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies...
Rabbit polyclonal OXCT1 antibody raised against the middle region of OXCT1 Background: CT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that...
Rabbit polyclonal OXCT1 antibody raised against the N terminal of OXCT1 Background: OXCT1 is a member of the 3-oxoacid CoA-transferase gene family. It is a homodimeric mitochondrial matrix enzyme that...
Rabbit polyclonal OXCT2 antibody raised against the middle region of OXCT2 Background: OXCT2 is a testis-specific succinyl-CoA:3-oxoac id CoA transferase (EC 2.8.3.5), which catalyzes the reversible transferof CoA from succinyl-CoA...
Rabbit polyclonal P2RX4 antibody raised against the N terminal of P2RX4 Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a...
Rabbit polyclonal P2RX5 antibody raised against the N terminal of P2RX5 Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a...
Rabbit polyclonal P4HB antibody raised against the C terminal of P4HB Background: P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein...
Rabbit polyclonal P4HB antibody raised against the N terminal of P4HB Background: P4HB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein...
Rabbit polyclonal PAFAH1B1 antibody raised against the N terminal of PAFAH1B1 Background: This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with...
Rabbit polyclonal PAFAH1B3 antibody raised against the middle region of PAFAH1B3 Background: This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of...
Rabbit polyclonal PAPPA2 antibody raised against the middle region of PAPPA2 Background: PAPPA2 is a metalloproteinase which specifically cleaves IGFBP-5. It shows limited proteolysis toward IGFBP-3.
Rabbit polyclonal PAPPA2 antibody raised against the N terminal of PAPPA2 Background: PAPPA2 is a metalloproteinase which specifically cleaves IGFBP-5. It shows limited proteolysis toward IGFBP-3.
Rabbit polyclonal PARD3 antibody Background: PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 mediates the establishment of cell...
Rabbit polyclonal PBK antibody raised against the N terminal of PBK Background: PBK is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests...
Rabbit polyclonal PCCB antibody raised against the middle region of PCCB Background: PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA.
Rabbit polyclonal PCOLCE antibody raised against the middle region of PCOLCE Background: PCOLCE binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.
Rabbit polyclonal PCSK1 antibody raised against the middle region of PCSK1 Background: PCSK1 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of...
Rabbit polyclonal PCSK5 antibody raised against the middle region of PCSK5 Background: PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process...
Rabbit polyclonal PDGFB antibody raised against the N terminal of PDGFB Background: PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic...
Rabbit polyclonal PDIA6 antibody raised against the middle region of PDIA6 Background: Protein disulfide isomerases, such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization...
Rabbit polyclonal PDIA6 antibody raised against the N terminal of PDIA6 Background: Protein disulfide isomerases, such as PDIA6, are endoplasmic reticulum (ER) resident proteins that catalyze formation, reduction, and isomerization...
Rabbit polyclonal PGCP antibody raised against the N terminal of PGCP Background: PGCP is a carboxypeptidase that may play an important role in the hydrolysis of circulating peptides.
Rabbit polyclonal PHGDH antibody raised against the middle region of PHGDH Background: 3-Phosphoglycerate dehydrogenase (PHGDH) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyru vate, which is the first and rate-limiting step...
Rabbit polyclonal PHYH antibody raised against the middle region of PHYH Background: This gene is a member of the PhyH family and encodes a peroxisomal protein that is involved in...
Rabbit polyclonal PIK3R4 antibody raised against the N terminal of PIK3R4 Background: The protein can regulate subunit of the PI3K complex and may regulate membrane trafficking late in the endocytic...
Rabbit polyclonal PKDREJ antibody raised against the middle region of PKDREJ Background: PkDaREJ is a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor...
Rabbit polyclonal PLA1A antibody raised against the middle region of PLA1A Background: Phosphatidylserine-s pecific phospholipase A1-alpha (PLA1A) acts specifically on phosphatidylserine (PS) and 1-acyl-2-lysophospha tidylserine (lyso-PS) to hydrolyze fatty acids...
Rabbit polyclonal PLA2G5 antibody raised against the middle region of PLA2G5 Background: This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster...
Rabbit polyclonal PLA2G5 antibody raised against the N terminal of PLA2G5 Background: This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster...
Rabbit polyclonal PLAC1L antibody raised against the middle region of PLAC1L Background: The function of PLAC1 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal Plasminogen antibody raised against the middle region of PLG Background: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted...
Rabbit polyclonal PLCB1 antibody Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and...
Rabbit polyclonal Pleiotrophin antibody Background: PTN is a heparin binding mitogenic protein. It has neurite extension activity.
Rabbit polyclonal Plexin A4 antibody raised against the middle region of PLXNA4 Background: This protein mediates semaphorin receptor activity.
Rabbit polyclonal PLK1 antibody Background: Serine/threonine-pro tein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the...
Rabbit polyclonal PLOD2 antibody raised against the middle region of PLOD2 Background: PLOD2 forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate...
Rabbit polyclonal PMS2 antibody Background: PMS2 is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations...
Rabbit polyclonal PNPLA4 antibody raised against the C terminal of PNPLA4 Background: PNPLA4 is a keratinocyte retinyl ester hydrolase. The protein also catalyzes fatty acyl CoA-dependent and independent retinol esterification,...
Rabbit polyclonal POFUT2 antibody raised against the N terminal of POFUT2 Background: POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue...
Rabbit polyclonal POLB antibody Background: In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance.
Rabbit polyclonal POLD2 antibody Background: This protein is a DNA polymerase delta complex, it is involved in DNA replication and repair.
Rabbit polyclonal POLK antibody Background: POLK belongs to the DNA polymerase type-Y family. It contains 2 Rad18-type zinc fingers and 1 umuC domain. POLK is a DNA polymerase specifically involved...
Rabbit polyclonal POLL antibody Background: POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in...
Rabbit polyclonal POLM antibody Background: POLM seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.
Rabbit polyclonal POLS antibody Background: The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required...
Rabbit polyclonal PON1 antibody raised against the C terminal of PON1 Background: PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad...
Rabbit polyclonal PON1 antibody raised against the middle region of PON1 Background: PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad...
Rabbit polyclonal PPOX antibody raised against the N terminal of PPOX Background: This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to...
Rabbit polyclonal PPP2R3B antibody Background: Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth...
Rabbit polyclonal PPP5C antibody raised against the N terminal of PPP5C Background: PPP5C may play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, PPP5C dephosphorylates serine...
Rabbit polyclonal PRELP antibody raised against the middle region of PRELP Background: PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule...
Rabbit polyclonal Presenilin 2 antibody Background: Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor...
Rabbit polyclonal Prohibitin antibody raised against the C terminal of PHB Background: Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative...
Rabbit polyclonal Protein C antibody Background: Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions...
Rabbit polyclonal PRR5 antibody Background: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor...
Rabbit polyclonal PRSS35 antibody raised against the N terminal of PRSS35 Background: The function of PRSS35 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal PSG5 antibody raised against the middle region of PSG5 Background: The pregnancy-specific beta 1 glycoprotein (PSG) is a group of heterogeneous proteins produced in large amounts by the...
Rabbit polyclonal PSMD1 antibody Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.
Rabbit polyclonal PTGDS antibody Background: PTGDS is a glutathione-independ ent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator...
Rabbit polyclonal PYCR1 antibody raised against the middle region of PYCR1 Background: This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxyl ate to proline. This enzyme may...
Rabbit polyclonal QPCT antibody Background: QPCT is responsible for the biosynthesis of pyroglutamyl peptides. QPCT has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and...
Rabbit polyclonal RAD54B antibody Background: RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and...
Rabbit polyclonal RAD54L antibody Background: This protein belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination...
Rabbit polyclonal RAD9B antibody Background: The function of RAD9B protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal Ran antibody raised against the middle region of RAN Background: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential...
Rabbit polyclonal RanGAP1 antibody raised against the N terminal of RANGAP1 Background: RanGAP1, is a homodimeric 65 kDa polypeptide that specifically induces the GTPase activity of RAN, but not of...
Rabbit polyclonal RBBP4 antibody raised against the N terminal of RBBP4 Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins.
Rabbit polyclonal RBBP6 antibody raised against the N terminal of RBBP6 Background: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular...
Rabbit polyclonal RBM14 antibody raised against the N terminal of RBM14 Background: RBM14 contains 2 RRM (RNA recognition motif) domains. Isoform 1 may function as a nuclear receptor coactivator, enhancing...
Rabbit polyclonal RBP4 antibody raised against the N terminal of RBP4 Background: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in...
Rabbit polyclonal RDH11 antibody Background: RHD11, a member of the short-chain dehydrogenase/reduct ase (SDR) superfamily of oxidoreductases, is expressed at high levels in prostate epithelium, and its expression is regulated...
Rabbit polyclonal RDH12 antibody Background: RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes...
Rabbit polyclonal RDH16 antibody Background: RDH16 is an oxidoreductase with a preference for NAD. It oxidizes all-trans-retinol and 13-cis-retinol to the corresponding aldehydes. RDH16 has higher activity towards CRBP-bound retinol...
Rabbit polyclonal Rec8 antibody Background: REC8 is required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I...
Rabbit polyclonal REG1B antibody raised against the N terminal of REG1B Background: REG1B might act as an inhibitor of spontaneous calcium carbonate precipitation. REG1B may be associated with neuronal sprouting...
Rabbit polyclonal RFC3 antibody Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication...
Rabbit polyclonal RFC4 antibody Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication...
Rabbit polyclonal RFC5 antibody Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication...
Rabbit polyclonal RIOK3 antibody Background: RIOK3 was identified by the similarity to the Aspergillus nidulans SUDD protein, an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly...
Rabbit polyclonal RMI1 antibody Background: RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit...
Rabbit polyclonal RNASE11 antibody Background: RNASE11 belongs to the pancreatic ribonuclease family. The function of RNASE11 remains unknown.
Rabbit polyclonal RNASEH2A antibody raised against the C terminal of RNASEH2A Background: Of the multiple RNases H in mammals, RNase HI is the major enzyme and shows increased activity during...
Rabbit polyclonal RPA1 antibody raised against the middle region of RPA1 Background: RPA1 plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair.
Rabbit polyclonal RPA4 antibody raised against the C terminal of RPA4 Background: Replication protein A (RPA) is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation.
Rabbit polyclonal RPA4 antibody raised against the middle region of RPA4 Background: Replication protein A (RPA) is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation.
Rabbit polyclonal RRM2 antibody raised against the N terminal of RRM2 Background: RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Rabbit polyclonal SCGB1A1 antibody Background: SCGB1A1 binds phosphatidylcholine, phosphatidylinositol , polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Rabbit polyclonal SCN1B antibody raised against the middle region of SCN1B Background: Voltage-gated sodium channels are essential for the generation and propagation of action potentials in striated muscle and neuronal...
Rabbit polyclonal SCN3B antibody raised against the N terminal of SCN3B Background: SCN3B is one member of the sodium channel beta subunits of voltage-gated sodium channels, which are responsible for...
Rabbit polyclonal SCNN1B antibody Background: When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways,...
Rabbit polyclonal SDF2 antibody raised against the middle region of SDF2 Background: SDF2 is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast...
Rabbit polyclonal Selenoprotein antibody raised against the middle region of 15 kDa Selenoprotein Background: SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in...
Rabbit polyclonal Semenogelin I antibody raised against the middle region of SEMG1 Background: SEMG1 is the predominant protein in semen. The secreted protein is involved in the formation of a...
Rabbit polyclonal Septin 11 antibody raised against the N terminal of 40432 Background: SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety...
Rabbit polyclonal Septin 12 antibody raised against the middle region of 40433 Background: Septins, such as SEPT12, are conserved GTP-binding proteins that function as dynamic, regulatable scaffolds for the recruitment...
Rabbit polyclonal Septin 2 antibody raised against the middle region of 40423 Background: SEPT2 is required for normal progress through mitosis. SEPT2 is involved in cytokinesis.
Rabbit polyclonal Septin 2 antibody raised against the N terminal of 40423 Background: SEPT2 is required for normal progress through mitosis. SEPT2 is involved in cytokinesis.
Rabbit polyclonal Serotonin receptor 3C antibody Background: HTR3C is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a...
Rabbit polyclonal Serotonin receptor 3E antibody Background: HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a...
Rabbit polyclonal SERPINA5 antibody raised against the C terminal of SERPINA5 Background: SERPINA5 belongs to the serpin family. It Inhibits activated protein C as well as plasminogen activators.
Rabbit polyclonal SERPINA5 antibody Background: SERPINA5 belongs to the serpin family. It Inhibits activated protein C as well as plasminogen activators.
Rabbit polyclonal SERPINC1 antibody Background: The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as...
Rabbit polyclonal SERPIND1 antibody Background: The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene...
Rabbit polyclonal SERPINE1 antibody raised against the C terminal of SERPINE1 Background: SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may...
Rabbit polyclonal SERPINE1 antibody raised against the N terminal of SERPINE1 Background: SERPINE1 acts as 'bait' for tissue plasminogen activator, urokinase, and protein C. Its rapid interaction with TPA may...
Rabbit polyclonal SERPINE2 antibody Background: SERPINE2 is the serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. SERPINE2 promotes neurite extension by inhibiting thrombin.
Rabbit polyclonal SERPINI1 antibody Background: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially...
Rabbit polyclonal SERPINI2 antibody Background: The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in...
Rabbit polyclonal SET antibody raised against the N terminal of SET Background: SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity...
Rabbit polyclonal SFN antibody raised against the middle region of SFN Background: SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized...
Rabbit polyclonal SFTPB antibody raised against the middle region of SFTPB Background: SFTPB is the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis...
Rabbit polyclonal SH3GL2 antibody raised against the middle region of SH3GL2 Background: SH3GL2 is implicated in synaptic vesicle endocytosis. SH3GL2 may recruit other proteins to membranes with high curvature.
Rabbit polyclonal SH3GL2 antibody raised against the N terminal of SH3GL2 Background: SH3GL2 is implicated in synaptic vesicle endocytosis. SH3GL2 may recruit other proteins to membranes with high curvature.
Rabbit polyclonal SLIT1 antibody Background: SLIT1 is thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors.
Rabbit polyclonal SMC2 antibody raised against the middle region of SMC2 Background: SMC2 belongs to the SMC family. It is a central component of the condensin complex, a complex required...
Rabbit polyclonal SMC4 antibody raised against the middle region of SMC4 Background: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into...
Rabbit polyclonal SMC4 antibody raised against the N terminal of SMC4 Background: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into...
Rabbit polyclonal SMPDL3B antibody raised against the N terminal of SMPDL3B Background: Located on chromosome 1, this gene encodes for acid sphingomyelinase-lik e phosphodiesterase 3b precursor protein.
Rabbit polyclonal SMR3A antibody raised against the middle region of SMR3A Background: SMR3A may play a role in protection or detoxification.
Rabbit polyclonal SPAG11B antibody raised against the N terminal of SPAG11B Background: SPAG11B is one of several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been...
Rabbit polyclonal SPINK1 antibody raised against the N terminal of SPINK1 Background: SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought...
Rabbit polyclonal SPO11 antibody Background: Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is...
Rabbit polyclonal ST8SIA4 antibody raised against the middle region of ST8SIA4 Background: ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of...
Rabbit polyclonal STAG3 antibody raised against the middle region of STAG3 Background: STAG3 is a meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of...
Rabbit polyclonal STATH antibody raised against the middle region of STATH Background: STATH is a salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium...
Rabbit polyclonal SYCP1 antibody raised against the N terminal of SYCP1 Background: SYCP1 is a major component of the transverse filaments of synaptonemal complexes (SCS), which is formed between homologous...
Rabbit polyclonal Synuclein Alpha antibody Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and...
Rabbit polyclonal Tachykinin 3 antibody Background: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Rabbit polyclonal TFPI2 antibody raised against the middle region of TFPI2 Background: TFPI2 may play a role in the regulation of plasmin-mediated matrix remodeling. It inhibits trypsin, plasmin, factor VIIa/tissue...
Rabbit polyclonal TGF beta 3 antibody raised against the middle region of TGFB3 Background: TGFB3 is involved in embryogenesis and cell differentiation.
Rabbit polyclonal TLK1 antibody raised against the N terminal of TLK1 Background: The Tousled-like kinases, first described in Arabadopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation...
Rabbit polyclonal TOR3A antibody raised against the middle region of TOR3A Background: The function of TOR3A protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal TPCN1 antibody raised against the N terminal of TPCN1 Background: TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane.Voltage-gat ed Ca(2+)...
Rabbit polyclonal TPTE antibody raised against the middle region of TPTE Background: TPTE encodes a putative transmembrane tyrosine phosphatase that may be involved in signal transduction pathways of the endocrine...
Rabbit polyclonal TPX2 antibody Background: TPX2 binding decreases the size and accessibility of a hydrophobic pocket, adjacent to the ATP site, to inhibitors.
Rabbit polyclonal TRAPPC4 antibody raised against the middle region of TRAPPC4 Background: TRAPPC4 may play a role in vesicular transport from endoplasmic reticulum to Golgi.
Rabbit polyclonal Tropomodulin 2 antibody Background: TMOD2 is a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. It caps the pointed end of actin filaments preventing both elongation and...
Rabbit polyclonal TRPC3 antibody raised against the n terminal of TRPC3 Background: TRPC3 is thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol...
Rabbit polyclonal TRPC6 antibody raised against the N terminal of TRPC6 Background: TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is...
Rabbit polyclonal TRPM4 antibody raised against the N terminal of TRPM4 Background: TRPM4 is a calcium-activated non selective (CAN) cation channel that mediates membrane depolarization. While it is activated by...
Rabbit polyclonal TRPM5 antibody raised against the N terminal of TRPM5 Background: TRPM5 is a voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a...
Rabbit polyclonal TRPM8 antibody raised against the N terminal of TRPM8 Background: TRPM8 is the receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated...
Rabbit polyclonal TRPV4 antibody raised against the middle region of TRPV4 Background: TRPV4 is a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential...
Rabbit polyclonal TRPV4 antibody raised against the middle region of TRPV4 Background: TRPV4 is a non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation of TRPV4...
Rabbit polyclonal TRPV5 antibody raised against the N terminal of TRPV5 Background: TRPV5 is a member of the transient receptor family and the TrpV subfamily. TRPV5, a calcium-selective channel, has...
Rabbit polyclonal TTC17 antibody raised against the N terminal of TTC17 Background: The function of TTC17 protein is not widely studied, and is yet to be elucidated fully.
Rabbit polyclonal UBA1 antibody raised against the N terminal of UBA1 Background: UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to...
Rabbit polyclonal UBE2C antibody raised against the middle region of UBE2C Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for...
Rabbit polyclonal UBE2C antibody raised against the N terminal of UBE2C Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for...
Rabbit polyclonal UBE3A antibody raised against the middle region of Ube3A Background: UBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally...
Rabbit polyclonal UBE3A antibody raised against the N terminal Of Ube3A Background: UBE3A is an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally...
Rabbit polyclonal UGCGL2 antibody raised against the middle region of UGCGL2 Background: UGCGL2 recognises glycoproteins with minor folding defects. UGCGL2 reglucosylates single N-glycans near the misfolded part of the protein,...
Rabbit polyclonal UGCGL2 antibody raised against the N terminal of UGCGL2 Background: UGCGL2 recognises glycoproteins with minor folding defects. UGCGL2 reglucosylates single N-glycans near the misfolded part of the protein,...
Rabbit polyclonal VPS29 antibody Background: This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein...
Rabbit polyclonal VSTM2A antibody raised against the middle region of VSTM2A Background: This pseudogene is a member of the cytochrome P450 geneuperfamily. The cytochrome P450 proteins are monooxygenases which catalyze...
Rabbit polyclonal WFDC5 antibody raised against the N terminal of WFDC5 Background: This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only...
Rabbit polyclonal WNT10B antibody raised against the middle region of WNT10B Background: WNT10B is the ligand for members of the frizzled family of seven transmembrane receptors. WNT10B is a probable...
Rabbit polyclonal WNT2 antibody raised against the middle region of WNT2 Background: WNT2 is the ligand for members of the frizzled family of seven transmembrane receptors. WNT2 is a probable...
Rabbit polyclonal WNT3A antibody raised against the N terminal of WNT3A Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins.
Rabbit polyclonal WNT5B antibody raised against the middle region of WNT5B Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been...
Rabbit polyclonal WRNIP1 antibody raised against the N terminal of WRNIP1 Background: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging. The protein encoded by this gene...
Rabbit polyclonal XPNPEP2 antibody Background: Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the...
Rabbit polyclonal XRCC2 antibody raised against the middle region of XRCC2 Background: XRCC2 is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability...
Rabbit polyclonal ZG16 antibody raised against the middle region of ZG16 Background: ZG16 may act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule...

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