Sartorius Lab Instruments GmbH & Co. KG Sartobran® P MidiCaps® 0.2 µm Liquid Filters 5235307H7--**--A

Sartobran P membrane filter MidiCaps are self contained, ready to use, sterile filter units for sterilizing grade filtration in the pharma| biotech industry. The extremely low unspecific adsorption of their cellulose acetate membranes assures highest protein yields and rapid preservative recovery. Applications: Sartobran P filter elements have proven throughout the years to be the first choice for all applications in the biopharmaceutical industry requiring low adsorption capabilities. They are typically used for sterilizing grade filtration of: – Coagulation Factors, Albumin, IgG – Bacterial & Viral Vaccines – MAB – Bio-processed Pharmaceuticals – Diagnostics – Purified Protein Solutions – Biological Fluids – Fluids containing preservatives. Easy to use: Sartobran P MidiCaps are delivered as individually packed sterile units. On site, pre-use sterilization can be eliminated. Flexibility: Sartobran P 0.2 µm MidiCaps are available with various filtration areas from 500cm² | 0.5 ft² up to 0.5m² | 5 ft² for easy adoption to any filtration process independent from the batch size. Scalability: Consistent and predictable scale-up and down trials can reliably be performed as all Sartobran P MidiCaps are produced with the same type of membrane and identical materials of construction. Cost Saving: The use of the disposable capsule design concept avoids investments into stainless steel filter housings and eliminates additional costs for cleaning of housings and cleaning validation. Microbiological Retention: Sartobran P MidiCaps 0.2 µm rated are fully validated as sterilizing grade filters according to HIMA and ASTM F-838-05 guidelines. Quality Control: Each individual element is tested for integrity by B.-P. and Diffusion-Test prior to be released assuring absolute reliability. Documentation: Sartobran P MidiCaps are designed, developed and manufactured in accordance with a ISO 9001 certified Quality Management System. A Validation Guide is available for compliance with regulatory requirements. Applications: Sartobran P filters are ideally suited for all applications that require highest product recovery rates like: Coagulation Factors, Albumine, IgG, Bacterial and Viral Vaccines, MAB's, Bio-processed Pharmaceuticals, Diagnostics, Purified Protein Solutions, Biological Fluids, Solutions containing Preservatives. Easy to Use: Sartobran P MidiCaps are delivered as individually packed sterile units. On site, pre-use sterilization can be eliminated. Flexibility: Sartobran P 0.2 µm filters are available in traditional cartridge formats and disposable capsules from 150 cm² to 1.8 m² for simple linear scale up and process flexibility. Scalability: Consistent and predictable scale-up and down trials can reliably be performed as all Sartobran P MidiCaps are produced with the same type of membrane and identical materials of construction. Cost Saving: The use of the disposable capsule design concept avoids investments into stainless steel filter housings and eliminates additional costs for cleaning of housings and cleaning validation. Microbiological Retention: Sartobran P 0.2 µm rated MidiCaps are fully validated as sterilizing grade filter elements according to HIMA and ASTM F-838-05 guidelines. Quality Control: Each individual element is integrity tested by diffusion and bubble point test prior to release, assuring absolute reliability. Documentation: Sartobran P MidiCaps are designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System. A Validation Guide and Extractables Guide are available for compliance with regulatory requirements.