Gelest, Inc. POLYMETHYLHYDROSILOXANE, TRIMETHYLSILYL TERMINATED, 15-25 cSt HMS-991

Safety Packaging Under Nitrogen Siloxane-Based Silane Reducing Agent Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure. Pendant Functional Fluid; polyMethylHydrosilox anes, TMS Terminated MethylHydrosiloxane homopolymers are used as water-proofing agents, reducing agents and as components in some foamed silicone systems. Poly(methylhydrosilo xane); Methyl hydrogen siloxane; Polysiloxanes, methyl hydrogen; Siloxanes and silicones, methyl hydrogen Viscosity: 15-25 cSt Molecular Weight: 1,400-1,800 g/mol Mol% Hydride: 100 Reduces lactones to lactols Reduces aldehydes, ketones, esters, lactones, triglycerides and epoxides to alcohols with zinc hydride catalysis With titanium tetraisopropoxide catalysis carries out reductive amination of ketones and aldehydes and the reduction of acids or esters to 1° alcohols With TBAF catalysis selectively reduces aldehydes over ketones Used to generate tri-n-butyltin hydride ‘in-situ’ and in a one-pot hydrostannylation/St ille coupling sequence Reduces esters to alcohols Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catal yzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007