Alpha Diagnostic International, Inc. Rat Exchange inhibitory peptide (XIP) Control/blocking peptide #1 XIP11-P

Rat Exchange inhibitory peptide (XIP) Control/blocking peptide #1 General Information NCX contains a highly basic region in the large hydrophilic, intracellular loop called XIP (Exchange inhibitory peptide; RRLLFYKYVYKRYRAGKQRG 20 aa), that inhibits Na-Ca+ exchange in cardiac sarcolemmal vesicles and in other cells. Little or no sequence SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 20-aa peptide from rat XIP (1); Designation (XIP11-P, control or blocking peptide) conjugated to KLH; epitope location ~ N-terminus SpCrossreactivity The 20 AA rat XIP is 100% conserved in mouse, rat, human, rabbit, dog, cat, frog XIP. It is 70% conserved in rat NCX2 and NCX3. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.