A.G. Scientific, Inc. Cambinol C-2214

Description
An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC50 = 56 μM) and SIRT2(IC50 = 59 μM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53.
Description
An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC50 = 56 μM) and SIRT2(IC50 = 59 μM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53.

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
Cambinol
C-2214
Cambinol C-2214
An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC50 = 56 μM) and SIRT2(IC50 = 59 μM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53.

An inhibitor of NAD-dependent deacetylase activity of human SIRT1 (IC50 = 56 μM) and SIRT2(IC50 = 59 μM). Acts as an antitumor agent. Treatment of BCL6-expressing Burkitt lymphoma cells with Cambinol induces apoptosis accompanied by hyperacetylation of BCL6 and p53.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number C-2214
Product Name Cambinol
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