Alpha Diagnostic International, Inc. Anti-human Topoisomerase II alpha (TOP2 alpha) IgG, aff pure TOP2A11-A

Anti-human Topoisomerase II alpha (TOP2 alpha) IgG, aff pure General Information The topology of the DNA is a crucial issue in different biological processes like recombination, replication, transcription, and chromatin remolding. DNA topoisomerases are enzymes that control the amount of supercoiling in DNA. Without topoisomeras, DNA SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 18-aa peptide from ~C-terminus of human topoisomerase II alpha (Cat # TOP2A11-P) control peptide SpCrossreactivity Top21A11-P sequence is 100% conserved in alternatively spliced isoforms 2-4 of human TOP2A protein. It is also conserved in g. pig, and pig (94%), mouse (87%), chicken (72%), and rat (88%) in TOP2 alpha proteins. No significant reaction is seen with TOP2 beta protein. Antibody cross-reactivity in various other species has not been studied For research use only, not for diagnostic or therapeutic use.