Alpha Diagnostic International, Inc. monoclonal Anti-Human Transferrin receptor 1 (TfR1) IgG # 2 TFR12-M

monoclonal Anti-Human Transferrin receptor 1 (TfR1) IgG # 2 General Information Elemental iron is required for a variety of normal cellular functions and vital for proper growth and development. Transferrin (Tf), a serum glycoprotein of ~80 kDa and synthesized in the liver, is the primary protein of inter-organ transport of nonheme SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2486-seconda ry-antibodies-mouse. htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20008-1 Form Antibody Pure IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen Purified recombinant human Tfr1 (~95 kDa) protein; epitope location ~ N-terminus SpCrossreactivity TfR12-M epitope has been localized to the cytoplasmic N-terminus (1-30 aa) of TfR1. This domain is missing is soluble TfR1. TFR12-M crossreact with TfR1 from mouse, rat, chicken, and hamster. No significant reactivity is seen with TfR2. other species. Antibody reactivity in other species is not established. Purified human TfR1 protein (Cat # TFR11-C) can be used a positive control. For research use only, not for diagnostic or therapeutic use.