Alpha Diagnostic International, Inc. Human Sod. Gluc. Transp. 2 (SGLT-2) Control/blocking peptide # 2 SG24-P

Human Sod. Gluc. Transp. 2 (SGLT-2) Control/blocking peptide # 2 General Information SGLT2/SLC5A2 (rat/mouse 670 aa; human 672 aa, chromosome 16p11.2) is the low affinity, high capacity Na+-glucose transporter located in the S1 segments of proximal tubules. It is ~60% identical with SGLT1. SGLT2 mediates saturable Na-dependent and phlo SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen A 16 AA peptide sequence (designated SG24-P; control peptide) from the C-terminal, cytoplasmic domain 6 of Human SGLT-2 (1) was synthesized, coupled to KLH SpCrossreactivity The Human SG24-P peptide sequence is ~73% conserved in rabbit and 71% in mouse SGLT2. No significant sequence homology exists with other SGLTs. For rat/mouse SGLT2, we recommend the use antibody #1, Cat # SG23-S that is made to the rat SGLT-2 peptide For research use only, not for diagnostic or therapeutic use.