Alpha Diagnostic International, Inc. Human Serotonin Transporter (SERT) Control/blocking peptide #2 SERT12-P

Human Serotonin Transporter (SERT) Control/blocking peptide #2 General Information Serotonin plays important physiological functions at the intestinal level, the human intestinal epithelial Caco-2 cells functionally express SERT, both at their apical and basolateral cell membranes. It is a 630-aa residue in all human (chr 17q11), rat an SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 19-aa peptide of Human SERT; Designated (SERT12-P or control peptide) conjugated to KLH; epitope location ~ Near N-terminus, 1st Extracellular domain SpCrossreactivity Human SERT12-P peptide sequence is 100% conserved in chimp, monkey, sheep, and bovine, 94% in horse and cat, 89% in chicken, mouse and rat serotonin transporter. Antibody crossreactivity in various species is not experimnetlaly condirmed For research use only, not for diagnostic or therapeutic use.