Alpha Diagnostic International, Inc. Anti-Human Presenilin 1 (PS-1) IgG # 1, aff pure PS11-A

Anti-Human Presenilin 1 (PS-1) IgG # 1, aff pure General Information An early onset of FAD has also been linked to some 30 mutations in two related genes, Presenilins-1 (PS-1 on chromosome 14; 467 aa) and Presenilins-2 (PS-2 on chromosome 1; 448 aa). Presenilins may contain 7-9 transmembrane domains. Presenilins are member SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 15-aa peptide of Human/Mouse PS1 ; Designated (PS11-P or control peptide) Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The immunogenic peptide sequences from Presenilin-1, PS11-P shows 100% homology to human, monkey, Xenopus, mouse and rat, 85% in bovine Presenilin-1. There is no significant homology with other known proteins. The Presenilin-1 antibody cross-reactivity in other species is not known For research use only, not for diagnostic or therapeutic use.