Alpha Diagnostic International, Inc. Mouse OBRb Phospho (Y1138) peptide (1133-1143) # 3 OBR17-P

Mouse OBRb Phospho (Y1138) peptide (1133-1143) # 3 General Information At least five genes, Obese (ob), diabetes (db), fat (fat), agouti yellow (Ay), and tubby (tub) have been linked to obesity. Obese gene encodes an adipocyte-tissue derived secreted protein Ob protein/Leptin (167 amino acid, ~16 kDa) that controls body weig SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen Control non-phosphorylated peptide (cat # OBR17-P) was used to negatively adsorb the phosphopeptide antiserum and making it specific for the OBRb-Tyr1138 SpCrossreactivity Mouse OBR16-P sequence is specific for the long isoform (OBRb). It is 91% conserved in rat, 64% in human OBRb. The antibody is specific for OBRb phosphorylated at Tyr1138. It does not react with non-phosphorylated OBRb or OBRb phosphorylated at Tyr985. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.