Alpha Diagnostic International, Inc. Anti-Human Alpha Defensin 4 (NP-4) antiserum #1 HDEFA41-S

Anti-Human Alpha Defensin 4 (NP-4) antiserum #1 General Information -defensins are encoded by genes designated DEFA1-6, whereas human -defensins are encoded by the DEFB1 and DEFb2 genes. HD1-4 are expressed in neutrophils, whereas HD5 and HD6 are expressed in epithelial cells of the intestinal and reproductive tract. SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen Human alpha 4 defensins (HDEFA4 or HNP-4) is synthesized from 97 precursor (mature peptide 64-96). A 17-aa peptide (designated HDEFA41-P; control peptides) Epitope location ~ near the C-terminus of human mature alpha defensin-4 (1) conjugated to KLH SpCrossreactivity The HDEFA41-P control peptides is specific for human to human HDEFA4 or HNP-4. No significant homology exists with other alpha-defensins. The HDEFA41-P control peptide is available for antibody blocking to confirm specificity of antibodies. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.