Cell-permeable. A potent, selective, non-transition state and non-competitive inhibitor of γ-secretase (IC50 = 0.3 nM for total β-amyloid) and Notch processing. At higher concentrations (20-400 μM), only weakly affects the presenilase activity.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | C-2269 |
| Product Name | Compound E |