Alpha Diagnostic International, Inc. Anti-Human histamine receptor 2 (H2R) IgG #2, aff pure H2R22-A

Anti-Human histamine receptor 2 (H2R) IgG #2, aff pure General Information The H2R (mouse/rat 358 aa; human 359 aa chromosome 5) causes cAMP accumulation in the gastric cells, cardiac tissues, smooth muscle cells and immune cells. H2R agonists have been proven to be effective for acid peptic disorders of the GI tract. H2R is m SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen An 18 aa peptide (Gene Accession #P25021) (designated H2R22-P control peptide) within the extracellular, N-terminus of human H2R (1) was synthesized, conjugated to KLH SpCrossreactivity The Human H2R22-P peptide sequence is 100% conserved in fish, 66% in canine, mouse and rat, 61% in guinea pig H2R. No significant homology exists with other histamine receptors. For rat, We recommend antibody cat # H2R21 made against the rat H2R sequence. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.