Alpha Diagnostic International, Inc. Mouse Telomerase/EST2 Control/blocking peptide # 3 EST23-P

Mouse Telomerase/EST2 Control/blocking peptide # 3 General Information Purification of telomerase from the ciliate also revealed two protein of 43 and 123 kDa. p123 is a homolog of yeast Est2 (Essential for Telomerase activity). Mammalian homologs of yeast Est2 (also known as TP2 for Telomerase associated Protein 2; hEST2 SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 15-aa peptide of mouse EST2 ; Designated (EST23-P or control peptide). epitope location ~ Mid-region SpCrossreactivity The 15 AA mouse EST23-P control peptide sequence is 100% conserved in rat and human (1). No significant sequence homology is seen with yeast telomerase. We recommend the use of EST24 for the detection of yeast enzyme. Control peptide is recommended for antibody blocking studies to confirm specificity of antibodies. Actual cross-reactivity of antibodies in various species has not been studied For research use only, not for diagnostic or therapeutic use.