A.G. Scientific, Inc. CDK1/2 Inhibitor III C-1447

Description
Cell permeable triazolo-diamine compound; displays anti-proliferative properties in human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).
Description
Cell permeable triazolo-diamine compound; displays anti-proliferative properties in human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).

Suppliers

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
CDK1/2 Inhibitor III
C-1447
CDK1/2 Inhibitor III C-1447
Cell permeable triazolo-diamine compound; displays anti-proliferative properties in human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).

Cell permeable triazolo-diamine compound; displays anti-proliferative properties in human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number C-1447
Product Name CDK1/2 Inhibitor III
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