Alpha Diagnostic International, Inc. Anti-Rat Chloride channel 1 (CLC1) Antiserum #2 CLC12-S

Anti-Rat Chloride channel 1 (CLC1) Antiserum #2 General Information Rat CLC-1 is 994 aa membrane protein (human CLC-1 988 aa) (1). It is predominantly expressed in skeletal muscles. Defects in CLC1 (CLCN1) are the cause of autosomal recessive generalized myotonia (Becker's disease) (RGM) and autosomal dominant myotonia SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 19aa peptide of rat CLC1; Designated (CLC12-P or control peptide). epitope location ~ N-terminus SpCrossreactivity The 19 AA rat CLC12-P control peptide 94% conserved in mouse, 84% in human and 57% in dog CLC-1. No significant sequence homology is detected with other CLCs or other proteins. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.