Alpha Diagnostic International, Inc. Rat Anion Exchanger 2 (AE2) Control/blocking peptide #2 AE21-P

Rat Anion Exchanger 2 (AE2) Control/blocking peptide #2 General Information Human AE2 gene (chromosome 7q35-q36) encodes a protein of 1241 aa (mouse 1237 aa, rat 1234 aa). Several isoforms of AE2 are also expressed as a result of alternative splicing. AE2 is widely expressed in many tissues. SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 21-aa peptide of Rat AE2/B3A2 (protein accession #P23347; refs 1) Designated (AE21-P or Control peptide) conjugated to KLH; epitope location ~ N-terminal, Cytoplasmic SpCrossreactivity Rat AE21-P control peptide is 100% conserved in mouse, 90% in rabbit, 85% in human, and 80% in chicken AE-2. No significant sequence homology is detected with other AE or other proteins. Actual cross-reactivity of antibodies in various species has not been studied For research use only, not for diagnostic or therapeutic use.