A.G. Scientific, Inc. VX-702 V-2481

Description
A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 μM) completely or partially inhibited platelet agonist induced p38 activation (IC50= 4 to 20 nM).
Description
A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 μM) completely or partially inhibited platelet agonist induced p38 activation (IC50= 4 to 20 nM).

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Company
Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
VX-702
V-2481
VX-702 V-2481
A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 μM) completely or partially inhibited platelet agonist induced p38 activation (IC50= 4 to 20 nM).

A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 μM) completely or partially inhibited platelet agonist induced p38 activation (IC50= 4 to 20 nM).

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number V-2481
Product Name VX-702
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