A.G. Scientific, Inc. Syk Inhibitor S-2449

Description
Cell-permeable. An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC50 = 14 nM). Has been shown to effectively inhibit FcîµRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC50 = 313 nM).
Description
Cell-permeable. An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC50 = 14 nM). Has been shown to effectively inhibit FcîµRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC50 = 313 nM).

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
Syk Inhibitor
S-2449
Syk Inhibitor S-2449
Cell-permeable. An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC50 = 14 nM). Has been shown to effectively inhibit FcîµRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC50 = 313 nM).

Cell-permeable. An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC50 = 14 nM). Has been shown to effectively inhibit FcεRI-mediated degranulation in the rat basophilic leukemia cell line, RBL-2H3 (EC50 = 313 nM).

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number S-2449
Product Name Syk Inhibitor
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