A potent inhibitor of sirtuin 2 (SIRT2) (IC50 = 3.5 μM). AGK2 is >15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued α-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinson's disease.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | S-2434 |
| Product Name | SIRT2 Inhibitor, AGK2 |
