A potent, cell-permeable, irreversible, and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (ICâ‚…â‚€=0.70 nM. Does not inhibit other protein kinases. Acts by binding to the catalytic domain of the EGFR with a 1:1 stoichiometry and alkylating Cysâ·â·³. Excellent antitumor agent in vivo.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | P-1653 |
| Product Name | PD 168393 |
