A.G. Scientific, Inc. ML130 M-2383

Description
Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC50 = 0.56&plusm;0.04 μM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-âº-induced NF-kB activation.
Description
Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC50 = 0.56&plusm;0.04 μM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-âº-induced NF-kB activation.

Suppliers

Company
Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
ML130
M-2383
ML130 M-2383
Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC50 = 0.56&plusm;0.04 μM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-âº-induced NF-kB activation.

Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC50 = 0.56&plusm;0.04 μM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in reporter cell lines containing both endogenous and overexpressed NOD2 proteins or TNF-âº-induced NF-kB activation.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number M-2383
Product Name ML130
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