Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS- treated wild type mice but has no effect on cytokine release from MIF deficient macrophages.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | M-2379 |
| Product Name | MIF-Antagonist, ISO-1 |
