An indolocarbazole derivative with antineoplastic properties. Acts as a potent inhibitor of several tyrosine kinases including FLT3, JAK2, and TrkA with IC50 values of 3, 1, and 25 nM, respectively. It suppresses JAK2/STAT5 signaling and is effective against myeloproliferative disorders in vivo.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | L-2374 |
| Product Name | Lestaurtinib |