A.G. Scientific, Inc. Bay 61-3606 Hydrochloride B-2195

Description
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 μM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.
Description
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 μM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
Bay 61-3606 Hydrochloride
B-2195
Bay 61-3606 Hydrochloride B-2195
Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 μM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.

Cell-permeable. A potent, ATP-competitive and reversible inhibitor of spleen tyrosine kinase (Syk) (IC50 = 10 nM). Displays excellent selectivity against many other kinases including Btk, Fyn, Itk, Lyn and Src up to concentrations of 4.7 μM. Shows good in vivo efficacy in the treatment of various allergy and asthma conditions in rat models.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number B-2195
Product Name Bay 61-3606 Hydrochloride
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