A.G. Scientific, Inc. A 83-01 A-1764

Description
A selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphrylation of Smad2 and inhibits TGF-β -induced epithelial-to-mesenc hymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs)
Description
A selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphrylation of Smad2 and inhibits TGF-β -induced epithelial-to-mesenc hymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs)

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
A 83-01
A-1764
A 83-01 A-1764
A selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphrylation of Smad2 and inhibits TGF-β -induced epithelial-to-mesenc hymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs)

A selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC50 values are 12, 45 and 7.5 nM respectively). Blocks phosphrylation of Smad2 and inhibits TGF-β -induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs)

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number A-1764
Product Name A 83-01
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