Description
Additional Properties
Hydrolytic Sensitivity 3: reacts with aqueous base Application Employed in plasma treatment of surfaces.1 Treatment of titanium alloys and stainless steel surfaces inhibits biofilm formation.2 Fieser F&F: Vol. 1, p 1235; Vol. 2, p 441; Vol. 13, p 101; Vol. 16, p 292. Reference 1. Hendricks, N. et al. Semiconductor Int'l. 2000, 23, 95. 2. Ma, Y. et al. Antimicrob. Agents Chemother. 2012, 56, 5923. Safety
Hazard Info ihl rat, LC50: >5,000 ppm/1H
Packaging Under Helium Tri-substituted Silane Reducing Agent Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure. Trimethylsilane, 3MS; 2-Methyl-2-silapropa
ne; Trimethylsilylhydrid
e
ΔHcomb: -3,206 kJ/mol
ΔHform: -163 kJ/mol
ΔHvap: 24.3 kJ/mol
Dipole moment: 0.52 debye
Vapor pressure, 25 °C: 1,218 mm
Critical temperature: 158.85 °C
Critical pressure: 31.48 atm
Potential reducing agent that will produce low boiling hexamethyldisiloxane by-product
Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catal
yzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007
