CONFIRM anti-Epidermal Growth Factor Receptor (EGFR) (3C6) Primary Antibody is directed against the extracellular domain of human EGFR, a protein of 170 kD. The antibody also recognizes the type III variant of 145 kD. EGFR is a member of the receptor tyrosine kinase HER family. Also known as HER1, EGFR is structurally related to HER2, HER3, and HER4. Members of this family are capable of forming heterodimers to elicit signal transduction. EGFR is expressed at low levels in most normal epithelial tissues, but can be over expressed in cancers of the breast, brain, bladder, lung, gastric, head and neck, esophagus, cervix, ovary, endometrium, and particularly in squamous cell carcinomas.
| Ventana Medical Systems, Inc. | |
|---|---|
| Product Category | Organic Chemicals |
| Product Number | 790-2988 |
| Product Name | CONFIRM EGFR (Epidermal Growth Factor Receptor) |
