Anti-Leukocyte Common Antigen (Anti-LCA) monoclonal antibody is routinely used to aid in the differential diagnosis of undifferentiated neoplasms, whenever malignant lymphomais suspected by the morphological or clinical data. It is a highly specific antibody therefore a positive result is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin's disease, some T-cell lymphomas and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes, erythrocytes, and plasma cell precursors.
Ventana Medical Systems, Inc. | |
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Product Category | Organic Chemicals |
Product Number | 760-4279 |
Product Name | CD45 (LCA) |