PSA is an antigen present in prostatic tissue and in the majority of prostatic carcinomas. This antibody recognizes primary and metastatic prostatic neoplasms and rarely in tumors of non-prostatic origin. These include breast and a minority of salivary gland tumors. The antigen is a 33-34 kD glycoprotein that is restricted to epithelial cells of the prostate. Animmunohistochemica
l study showed more than 95% of prostatic carcinomas stained with anti-PSA8. PSA is demonstrable in the cytoplasm of acinar and ductal cells of normal ormalignant prostate tissue.
PSA is an antigen present in prostatic tissue and in the majority of prostatic carcinomas. This antibody recognizes primary and metastatic prostatic neoplasms and rarely in tumors of non-prostatic origin. These include breast and a minority of salivary gland tumors. The antigen is a 33-34 kD glycoprotein that is restricted to epithelial cells of the prostate. Animmunohistochemical study showed more than 95% of prostatic carcinomas stained with anti-PSA8. PSA is demonstrable in the cytoplasm of acinar and ductal cells of normal ormalignant prostate tissue.
