Ventana Medical Systems, Inc. Chromogranin A 760-2519

Anti-Chromogranin A (LK2H10) specifically binds to the chromogranin A protein located in the secretory granules of normal and neoplastic neuroendocrine cells. Chromogranin A is also expressed by adrenal (medulla), parathyroid, anterior pituitary cells, islet cells of the pancreas, gastrointestinal cells, bronchial endocrine cells, and thyroid C cells. Chromogranin A is expressed in tumors of neuroendocrine origin, including pheochromocytomas, pituitary adenomas, islet cell tumors, medullary thyroid carcinomas, carcinoids and Merkel cell tumors. This reagent may be used to aid in the identification of cells of normal or neoplastic neuroendocrine lineage.