The Hamilton PRP-C18 is a reversed-phase HPLC column engineered for high-efficiency separations across a broad pH range (1-13) and temperatures up to 100°C, with a rigid, inert stationary phase resistant to degradation under aggressive conditions. This 21.2 x 250 mm variant uses 12-20 µm particle size and is designed for applications requiring extended column life in pharmaceutical, clinical, and environmental analysis. It enables rapid separations, reliable performance in alkaline mobile phases, and improved efficiency at elevated temperatures without shrinkage or swelling.
The Hamilton PRP-C18 is a new HPLC column designed to provide high-efficiency, reversed-phase separations over an extended column life in nearly any mobile phase or pH. The rigid stationary phase has excellent mechanical and thermal stability (> 100°C), does not shrink or swell, and is completely inert to most conditions commonly encountered in reversed-phase chromatography.
The PRP-C18 is a durable and effective column for general purpose HPLC and especially well-suited for specialized applications in the clinical, pharmaceutical, environmental, food, forensics, and life sciences industries.
Oligonucleotide Purification
The properties of the PRP-C18 make it a superior column in the field of oligonucleotide purifications, providing:
Applications:
Organic compounds: small molecules (< 2,000 mw), pharmaceuticals, steroids, halides, vitamins, amino acid analysis, herbicides
Examples of analytes that can be separated on PRP-C18 columns:
| Hamilton Company | |
|---|---|
| Product Category | HPLC Columns |
| Product Number | 79678 |
| Product Name | PRP-C18, 12-20 µm, 100 Å, 21.2 x 250 mm |
| Column Type | Analytical |
| Stationary Phase/Separation Process | Reversed Phase |
| Construction Material | Stainless Steel |
| Packing Diameter | 12 µm (0.4724 mils) |
| Pore Diameter | 0.0100 µm (3.94E-4 mils) |
