A.G. Scientific, Inc. L-685, 458 L-2369

Description
Cell-permeable. A potent and selective î³-secretase inhibitor (IC50 = 17 nM) .Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC50 values are 48 and 67 nM respectively in human neuroblastoma cells).
Description
Cell-permeable. A potent and selective î³-secretase inhibitor (IC50 = 17 nM) .Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC50 values are 48 and 67 nM respectively in human neuroblastoma cells).

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Description
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A.G. Scientific, Inc.
San Diego, CA, USA
L-685, 458
L-2369
L-685, 458 L-2369
Cell-permeable. A potent and selective î³-secretase inhibitor (IC50 = 17 nM) .Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC50 values are 48 and 67 nM respectively in human neuroblastoma cells).

Cell-permeable. A potent and selective γ-secretase inhibitor (IC50 = 17 nM) .Displays > 50-fold selectivity over a range of aspartyl, serine and cysteine proteases. Exhibits equal potency for inhibition of Aβ40 and Aβ42 peptides (IC50 values are 48 and 67 nM respectively in human neuroblastoma cells).

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number L-2369
Product Name L-685, 458
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