Latrunculin B is an actin filament modulator. 10 to 100-fold more potent than cytochalasins. Where cytochalasin D induces dissolution of F-actin and stress fiber contraction in fibroblasts in culture,
Latrunculin B causes stress fibers to shortening and thicken. Effects N1E-115 cells (mouse neuroblastoma) at starting concentrations of 90 nM (NI43T3 cells, 0.9 μM). Maximum effect at 2.5 μM. Fetal Bovine serum will slowly inactivate. Inhibits cofilin-actin binding (ED50~50 μM).
Attached is a published reference from researchers who have used our Latrunculin B product. We respectfully thank them for their trust in our product. Inquire for a full reference list.
http://ajpcell.physi
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | L-1057 |
| Product Name | Latrunculin B | CAS# [76343-94-7] | Actin filament modulator. |
